Evaluate Gunjaphaladi Lepam and Vibhitakadi Kwatha for Vitiligo.
Journal name: Ayushdhara
Original article title: To Evaluate the Efficacy of Gunjaphaladi Lepam and Vibhitakadi Kwatha in Management of Switra w.s.r to Vitiligo
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Mada Avinash Reddy
PG Scholar, Department of Kaumarabhritya, S.V. Ayurvedic College and Hospital, T.T.D., Tirupati, Andhra Pradesh, India.
Ragamala K.C
Assistant Professor, Department of Kaumarabhritya, S.V. Ayurvedic College and Hospital, T.T.D., Tirupati, Andhra Pradesh, India.
B.Harinathachary
Associate Professor, Department of Kayachikitsa, S.V. Ayurvedic College and Hospital, T.T.D., Tirupati, Andhra Pradesh, India.
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: To Evaluate the Efficacy of Gunjaphaladi Lepam and Vibhitakadi Kwatha in Management of Switra w.s.r to Vitiligo
Year: 2023 | Doi: 10.47070/ayushdhara.v10i1.1124
Copyright (license): CC BY-NC-SA 4.0
Download the PDF file of the original publication
Summary of article contents:
Introduction
Switra, classified under Kushta roga in Ayurveda, is characterized by white discoloration of the skin, commonly associated with vitiligo, a chronic autoimmune disorder affecting 0.5-2% of the global population. The study highlights the efficacy of two Ayurvedic formulations, Gunjaphaladi Lepam and Vibhitakadi Kwatha, in managing Switra in children aged 6-16 years. The aim was to evaluate their effectiveness while considering the principles of Shamana therapy, which is preferred in pediatric cases due to its gentler approach compared to Shodhana therapy.
Efficacy of Gunjaphaladi Lepam
Gunjaphaladi Lepam consists of Gunja (seed) and Chitraka (root), both known for their therapeutic properties in skin diseases. The preparation involves a traditional process where Gunja seeds are boiled in cow's milk for purification, and Chitraka is treated to enhance its medicinal efficacy. The paste is applied to affected areas and exposure to sunlight is recommended to facilitate absorption of beneficial properties. The clinical study noted that out of 30 patients treated, 56.66% showed mild improvement, while 17% experienced complete remission of symptoms, indicating the potential effectiveness of this treatment in managing the skin condition.
Role of Vibhitakadi Kwatha
Vibhitakadi Kwatha is another formulation used internally for treating Switra. It comprises Vibhitaki and Kakodumbara bark, along with Bakuchi seeds and jaggery. The preparation involves creating a decoction that is administered based on the age and condition of the patient. The properties of these ingredients target the underlying dosha imbalances contributing to skin disorders. Results from the study showed statistically significant improvements in the symptoms of Switra, highlighting Vibhitakadi Kwatha's beneficial role in conjunction with Gunjaphaladi Lepam for achieving better skin health.
Conclusion
The clinical evaluation demonstrates that both Gunjaphaladi Lepam and Vibhitakadi Kwatha are safe and effective remedies for managing Switra in children, showing notable improvements in symptoms after treatment with minimal side effects. Early diagnosis and timely treatment are crucial for better prognosis, particularly in cases where the condition is acute rather than chronic. Overall, the findings underscore the potential of Ayurvedic therapies in treating chronic skin conditions like vitiligo, advocating for extended treatment durations for optimal outcomes in chronic cases.
FAQ section (important questions/answers):
What condition does the study evaluate treatments for?
The study evaluates the efficacy of Gunjaphaladi Lepam and Vibhitakadi Kwatha in managing Switra, which is correlatively discussed as vitiligo, a chronic skin condition characterized by white patches due to loss of melanocytes.
What were the results of the efficacy evaluation?
Out of 30 patients, 56.66% experienced mild improvement, 17% had complete improvement, and 13.33% showed moderate improvement, indicating the treatments are generally effective and safe for managing Switra in children.
What is the duration of the treatment in the study?
The treatment duration in the study was 60 days, after which follow-ups were conducted to assess the efficacy and any changes in the patients' conditions.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Evaluate Gunjaphaladi Lepam and Vibhitakadi Kwatha for Vitiligo.�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Vibhitakadi:
Vibhitakadi refers to a formulation that includes Vibhitaki as one of its key ingredients. In this context, Vibhitakadi Kwatha is used as an internal treatment for Switra, which is related to vitiligo, meant to balance the involved Doshas and improve skin pigmentation.
2) Pitta:
Pitta is one of the three Doshas in Ayurveda responsible for metabolism and transformation in the body, including digestive and cellular metabolism. In the context of Switra, Pitta impairment particularly Bhrajaka Pitta present in the skin is implicated in the disorder's pathogenesis.
3) Rakta:
Rakta, meaning 'blood', is one of the Dhatus or bodily tissues in Ayurveda. In Switra, or vitiligo, Rakta plays a critical role as its vitiation can affect skin health, leading to discoloration and other symptoms. Treatments often aim to pacify Rakta along with other Doshas.
4) Disease:
In the given text, disease refers to Switra, an Ayurvedic term for a condition characterized by white patches on the skin, corresponding to vitiligo in modern medicine. It involves the disturbance of Doshas and Dhatus, leading to the destruction of melanocytes and depigmentation.
5) Kapha:
Kapha is another of the three Doshas in Ayurveda, associated with structure and stability in the body. In Switra's pathology, Kapha's impairment alongside Pitta and Vata can lead to imbalance and contribute to the disease process, necessitating treatments that restore Kapha balance.
6) Rasa (Rasha):
Rasa in Ayurveda refers to the bodily fluids that sustain cells and tissues. It is also the first among the seven Dhatus. In Switra, the disturbance in Rasa can contribute to the disease’s manifestations, necessitating therapies that restore its balance.
7) Virya:
Virya refers to the potency or inherent strength of a substance in Ayurveda, which can be Ushna (hot) or Shita (cold). In the context of Switra, the treatments used like Gunjaphaladi Lepam have Ushna Virya properties that are essential for breaking the disease’s pathogenic cycle.
8) Katu:
Katu is the pungent taste in Ayurveda, which has properties useful in detoxification and stimulating digestion. Both Gunja and Chitraka possess Katu Rasa, making them appropriate ingredients in Gunjaphaladi Lepam for treating skin disorders like Switra.
9) Guda:
Guda, or jaggery, is used in the Vibhitakadi Kwatha formulation. It has multiple beneficial properties in Ayurveda including being Tridoshahara (balancing all three Doshas), and promoting Rasa and Dhatu Prasadana. It also enhances the palatability and efficacy of the medicine.
10) Kashaya (Kasaya):
Kashaya is an astringent taste in Ayurveda. Vibhitaki, an ingredient in Vibhitakadi Kwatha, has Kashaya Rasa, which helps to pacify Pitta and Kapha Doshas. This taste is particularly useful in conditions needing stabilization and drying effects.
11) Gunja (Gumja):
Gunja is an Ayurvedic herb used in the treatment of skin diseases like Switra. It has Tikta (bitter) and Kashaya (astringent) Rasas, Ushna Virya (hot potency), and is a key ingredient in Gunjaphaladi Lepam. It helps to balance Kapha and Pitta Doshas.
12) Drug:
[see source text or glossary: Drug]
13) Rukshata (Ruksata):
Rukshata refers to dryness of the skin, a symptom observed in Switra. Treatments like Gunjaphaladi Lepam aim to alleviate Rukshata by restoring moisture and balance to the skin through its therapeutic properties.
14) Tikta:
Tikta is the bitter taste in Ayurveda, which has detoxifying and regenerative properties. Many herbs used in Switra treatment, such as Chitraka and Bakuchi, have Tikta Rasa, enhancing their effectiveness in clearing skin discolorations and aiding in melanogenesis.
15) Vata:
Vata is one of the three Doshas in Ayurveda, governing movement and bodily functions. Imbalance in Vata, particularly when obstructed by Kapha, contributes to Switra’s pathology. Treatments like Gunjaphaladi Lepam and Vibhitakadi Kwatha aim to re-balance Vata for therapeutic effect.
16) Kakodumbara:
Kakodumbara is a medicinal plant used in the preparation of Vibhitakadi Kwatha. With properties like Tikta (bitter) and Kashaya (astringent) Rasas, it is recognized for treating skin conditions and is an essential part of the remedy for Switra.
17) Powder:
[see source text or glossary: Powder]
18) Dosha (Dosa):
Dosha refers to the three fundamental bodily humors in Ayurveda: Vata, Pitta, and Kapha. Switra involves vitiation of these Doshas, necessitating treatments that focus on balancing them to restore health and skin pigmentation.
19) Laghu:
Laghu means light in Ayurveda. Herbs with Laghu Guna (qualities) are easy to digest and usually counter heaviness and Kapha. For example, Vibhitaki used in Vibhitakadi Kwatha has Laghu Guna and helps in balancing the body's Doshas.
20) Mamsa (Mamsha):
Mamsa is the muscle tissue in the body, one of the seven Dhatus in Ayurveda. In Switra, Mamsa Dhatu can be involved, especially when the condition manifests as coppery-colored patches, indicating deeper tissue disturbance.
21) Ushna (Usna):
[see source text or glossary: Usna]
22) Lepa:
Lepa refers to a type of Ayurvedic topical treatment or paste. In the treatment of Switra, Gunjaphaladi Lepam is applied externally to provide local therapeutic effects, such as improving pigmentation and balancing the Doshas in the affected area.
23) Vibhitaki:
Vibhitaki is an Ayurvedic herb, also known as Terminalia bellirica. It is a primary ingredient in Vibhitakadi Kwatha, known for its Kashaya Rasa and Laghu Guna, which help in treating skin disorders by balancing Kapha and Pitta Doshas.
24) Ruksha (Ruksa):
Ruksha refers to dryness, a Guna or quality in Ayurveda. Herbs like Vibhitaki that have Ruksha Guna are used in formulations like Vibhitakadi Kwatha to treat Switra by reducing excess moisture and Kapha in the body.
25) Guna:
[see source text or glossary: Guna]
26) Pittahara (Pitta-hara):
[see source text or glossary: Pitta-hara]
27) Samana (Shamana):
Shamana refers to pacifying or balancing treatments in Ayurveda. In the management of Switra in children, Shamana therapies like Gunjaphaladi Lepam and Vibhitakadi Kwatha are preferred over Shodhana (purification) due to their gentle action.
28) Vipaka:
Vipaka is the post-digestive effect of a substance in Ayurveda. For instance, Bakuchi has Katu Vipaka, which supports its efficacy in promoting skin health and treating Switra by aiding the digestive process and balancing Doshas.
29) Kandu (Kamdu):
Kandu indicates itching, a symptom observed in certain skin conditions. In the treatment of Switra, resolving Kandu is one of the therapeutic objectives, although the study noted its absence among the patients evaluated.
30) Dhatu:
Dhatu refers to the fundamental tissues that constitute the human body in Ayurveda. Switra affects Dhatus like Rakta (blood), Mamsa (muscle), and Meda (fat), necessitating treatments that restore balance among these tissues.
31) Mada:
[see source text or glossary: Mada]
32) Daha:
Daha translates to burning sensation in Ayurveda. It's a symptom that can occur in skin conditions like Switra. Effective treatment aims to alleviate Daha along with other associated symptoms to restore skin health.
33) Burning sensation:
Burning sensation, referred to as Daha in the source text, is a symptom often associated with skin disorders. The treatments, such as Gunjaphaladi Lepam, aim to relieve this symptom to improve overall skin condition in Switra patients.
34) Bhrajakapitta (Bhrajaka-pitta):
Bhrajaka Pitta is a subtype of Pitta Dosha responsible for skin color and temperature. In Switra, any impairment of Bhrajaka Pitta can lead to loss of skin pigmentation. Treatments focus on correcting this imbalance to restore skin health.
35) Kaumarabhritya (Kaumarabhrtya, Kaumara-bhritya):
Kaumarabhritya is the branch of Ayurveda focusing on pediatric care. The study from the Department of Kaumarabhritya at S.V. Ayurvedic Hospital evaluated the efficacy of Gunjaphaladi Lepam and Vibhitakadi Kwatha in treating Switra in children.
36) Ayurveda (Ayus-veda):
Ayurveda is the ancient Indian system of medicine that employs holistic approaches to treat various ailments including Switra (vitiligo). Its treatments focus on balancing the body's Doshas and Dhatus through natural therapies and lifestyle modifications.
37) Shodhana (Sodhana):
Shodhana involves cleansing and purification treatments in Ayurveda. While effective, Shodhana is typically less preferred for pediatric patients with Switra who are treated using milder Shamana therapies to balance their Doshas and improve symptoms.
38) Bhrajaka:
Bhrajaka refers to a type of Pitta located in the skin, responsible for skin color and aiding in absorption of treatments. Correcting Bhrajaka Pitta imbalance is crucial in the management of Switra to restore normal skin pigmentation.
39) Tirupati (Thirupati, Tiruppati):
[see source text or glossary: Tirupati]
40) Jaggery:
Jaggery, also referred to as Guda in the source text, is a component of Vibhitakadi Kwatha. It enhances the formulation's palatability, helps in balancing the Doshas, and improves skin conditions by providing essential minerals like copper and iron.
41) Phala:
In the context of Vibhitakadi Kwatha, Phala refers to the fruit part of the Vibhitaki plant (Terminalia bellirica), used for its medicinal properties. It is processed to create a decoction aimed at treating Switra by balancing the Doshas.
42) Karma (Karman):
Karma refers to the action or therapeutic effect of a treatment in Ayurveda. For instance, the Karma of Gunjaphaladi Lepam and Vibhitakadi Kwatha includes balancing the Doshas, reducing symptoms, and improving skin pigmentation in Switra patients.
43) Blood:
Blood, translated as Rakta in Ayurveda, is one of the Dhatus implicated in Switra. The pathology may involve Rakta Pradosha (vitiation of blood), and treatments aim to purify and balance Rakta to restore normal skin pigmentation.
44) Hara:
[see source text or glossary: Hara]
45) Roga:
[see source text or glossary: Roga]
46) Agni:
Agni refers to the digestive fire or metabolic process in Ayurveda. Proper Agni is crucial for the processing and assimilation of treatments. In Switra management, treatments aim to stimulate and maintain Agni to ensure effective digestion and healing.
47) Mula:
Mula means root in Ayurveda. It is often used in herbal medicine, such as Chitraka Mula (root of Plumbago zeylanica) in Gunjaphaladi Lepam, valued for its therapeutic properties in treating skin conditions like Switra by balancing the Doshas.
48) Hair:
Kesha (hair) is often examined in Ayurvedic diagnoses and treatments. In Switra, the condition of hair, such as discoloration, can be a diagnostic criterion. Treatments do not just focus on curing visible symptoms but also the associated structures like hair.
49) Pittadosha (Pittadosa, Pitta-dosha):
Pitta Dosha governs metabolism and transformation processes in the body. Imbalance in Pitta, particularly Bhrajaka Pitta in the skin, plays a significant role in Switra. Ayurvedic treatments aim to balance Pitta Dosha to restore skin health and pigmentation.
50) Medicine:
[see source text or glossary: Medicine]
51) Yantra (Yamtra):
[see source text or glossary: Yantra]
52) Vikara:
[see source text or glossary: Vikara]
53) Srotas (Shrotas):
[see source text or glossary: Srotas]
54) Medas (Meda, Medash):
[see source text or glossary: Medas]
55) Genetic disorder:
[see source text or glossary: Genetic disorder]
56) Kashyapasamhita (Kasyapasamhita, Kashyapa-samhita):
[see source text or glossary: Kashyapa-samhita]
57) Tridoshahara (Tridosahara, Tridosha-hara):
[see source text or glossary: Tridoshahara]
58) Madhurarasa (Madhura-rasa):
[see source text or glossary: Madhura-rasa]
59) Anabhishyandin (Anabhisyandin, Anabhisyandi, Anabhishyandi):
[see source text or glossary: Anabhisyandi]
60) Dolayantra (Dola-yantra, Dolayamtra):
[see source text or glossary: Dola-yantra]
61) Raktadhatu (Rakta-dhatu):
[see source text or glossary: Rakta-dhatu]
62) Mamsadhatu (Mamsha-dhatu):
[see source text or glossary: Mamsa-dhatu]
63) Kaphapitta (Kapha-pitta):
[see source text or glossary: Kapha-pitta]
64) Vatadosha (Vatadosa, Vata-dosha):
[see source text or glossary: Vata-dosha]
65) Kaphavata (Kapha-vata):
[see source text or glossary: Kapha-vata]
66) Discussion:
[see source text or glossary: Discussion]
67) Prasadana:
[see source text or glossary: Prasadana]
68) Tridosha (Tridosa, Tri-dosha):
[see source text or glossary: Tridosha]
69) Vatahara (Vata-ahara):
[see source text or glossary: Vata-hara]
70) Katurasa (Katu-rasa):
[see source text or glossary: Katu-rasa]
71) Lakshana (Laksana):
[see source text or glossary: Lakshana]
72) Kashyapa (Kasyapa, Kashya-pa, Kashyapanamdana):
[see source text or glossary: Kashyapa]
73) Ragamala (Raga-mala):
[see source text or glossary: Ragamala]
74) Romakupa (Roman-kupa):
[see source text or glossary: Romakupa]
75) Prakriti (Prakrti):
[see source text or glossary: Prakriti]
[Note: The above list is limited to 75. Total glossary definitions available: 111]
Other Science Concepts:
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Guda, Tridosha, Clinical study, Shodhana Therapy, Shamana Therapy, Statistically Significant, Exclusive criteria, Autoimmune disorder, Kushta Roga, Chronic skin disease, Inclusive Criteria, Potent Formulation, Melanocyte, Symptoms of Switra, Clinical parameter, Depigmentation Disorder, Pediatric group.