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Comparative study of kadamba bark and leaf in medoroga treatment.

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Journal name: Ayushdhara
Original article title: Comparative clinical study of kadamba (anthocephalus cadamba (roxb.) miq) bark and leaf in medoroga
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Author(s):

Swetha.Ch*
PG Scholar, Department of Dravyaguna, Dr.B.R.K.R.Govt.Ayurvedic College, Hyderabad, Telangana
V.Narasimha
Assistant Professor, Department of Dravyaguna, Dr.B.R.K.R.Govt.Ayurvedic College, Hyderabad, Telangana


Ayushdhara:

(A peer-reviewed, bi-monthly open-access journal)

Full text available for: Comparative clinical study of kadamba (anthocephalus cadamba (roxb.) miq) bark and leaf in medoroga

Year: 2019

Copyright (license): CC BY-NC-SA 4.0


Download the PDF file of the original publication


Summary of article contents:

Introduction

The article presents a comparative clinical study on the efficacy of Kadamba (Anthocephalus cadamba) bark and leaves in the treatment of Medoroga, a condition associated with hyperlipidemia. Recognized as a valuable traditional medicine system by the World Health Organization, Ayurveda emphasizes the importance of herbal plants in treating various health issues. The study acknowledges the growing health problems attributed to modern sedentary lifestyles, which lead to diseases like hyperlipidemia, and explores the beneficial properties of Kadamba, which has been mentioned in classical Ayurvedic texts for treating such disorders.

Efficacy of Kadamba in Hyperlipidemia

Kadamba has shown significant results in alleviating the symptoms associated with hyperlipidemia. The clinical trial involved 30 patients, divided into two groups, receiving Kadamba bark and leaf for 40 days. Results indicated that both forms of Kadamba were effective in improving symptoms such as fatigue, excessive sweating, and increased appetite, which are associated with Medoroga. Statistical analysis revealed that the leaf was more effective than the bark, suggesting its potential as a primary choice in managing hyperlipidemia.

Impact on Lipid Profiles

The study also assessed the effects of Kadamba on lipid profiles, focusing on parameters such as total cholesterol, LDL, HDL, and triglycerides. The findings showed that both Kadamba bark and leaf significantly improved lipid profiles, with the leaf demonstrating a greater percentage of improvement in various lipid levels. A notable increase in desirable HDL levels and a decrease in harmful lipid concentrations were observed in patients treated with both the bark and the leaf, reinforcing the validity of Kadamba as an effective treatment option for hyperlipidemia.

Conclusion

This clinical study confirms the therapeutic potential of Kadamba bark and leaf in the management of Medoroga and hyperlipidemia, with the leaf proving to be slightly more efficacious than the bark. Despite the promising results, the study acknowledges the limitations of a small sample size and calls for further research to validate its findings across larger populations and with additional health parameters. Ultimately, this work illustrates the relevance of traditional herbal medicine in contemporary health care and highlights the need for continued exploration of Ayurvedic treatments.

FAQ section (important questions/answers):

What is the main focus of the study on Kadamba?

The study evaluates the clinical efficacy of Kadamba bark and leaf in treating Medoroga, which refers to hyperlipidemia, and compares the effectiveness of both parts of the plant over a 40-day treatment period.

What were the key findings regarding Kadamba's effectiveness?

Both Kadamba bark and leaf proved effective in managing Medoroga symptoms and normalizing lipid profiles, with the leaf showing slightly greater efficacy compared to the bark based on statistical analyses of clinical outcomes.

What inclusion criteria were used for patient selection?

Patients included in the study had symptoms of Medoroga, were aged between 20 to 60 years, and exhibited elevated levels in their lipid profiles, while those with certain health conditions and younger or older ages were excluded.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Comparative study of kadamba bark and leaf in medoroga treatment.�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Kadamba:
Kadamba refers to a medicinal plant known scientifically as Anthocephalus Cadamba (Roxb.) Miq. It is used in treating various ailments including Medoroga, which is associated with hyperlipidemia, or high cholesterol levels. Both the bark and leaves of Kadamba have been studied for their efficacy. The leaves were found to be slightly more effective than the bark.

2) Medoroga (Medas-roga):
Medoroga is an Ayurvedic term that corresponds to hyperlipidemia in modern medicine. It is characterized by an imbalance in metabolism leading to increased lipid levels in the bloodstream. Symptoms include fatigue, excessive thirst, and obesity-related issues. Kadamba is used to manage this condition effectively.

3) Powder:
In the study, powder derived from both the bark and leaves of the Kadamba plant was used for treatment. The powders were prepared by drying and pulverizing the plant parts and stored in airtight containers. Patients received the powders in specific dosages to assess their efficacy in treating Medoroga.

4) Atinidra:
Atinidra is a symptom of Medoroga that translates to excessive sleepiness or drowsiness. It is one of the clinical parameters assessed in the study. Reduction in Atinidra indicates an improvement in the patient's condition, attributed to the treatment with Kadamba.

5) Utsahahani:
Utsahahani translates to a lack of enthusiasm, another symptom of Medoroga. The study measured changes in this symptom to gauge the effectiveness of Kadamba treatment. The results showed significant improvement in Utsahahani, suggesting the therapeutic potential of the plant.

6) Drug:
In the context of the study, Kadamba is referred to as a 'drug' used in Ayurvedic medicine to treat Medoroga. The term 'drug' denotes any medicinal substance used for treatment. Kadamba has several pharmacological properties such as Kaphaghna and Medohara, making it suitable for managing hyperlipidemia.

7) Ayurveda (Ayus-veda):
Ayurveda is a traditional system of medicine recognized by the World Health Organization. It encompasses a holistic approach to health and well-being, utilizing natural plants and herbs like Kadamba for treatment. Medoroga is an example of a condition addressed by Ayurvedic principles and treatments.

8) Disease:
In this study, 'disease' refers to Medoroga or hyperlipidemia. Diseases are generally characterized by specific symptoms and clinical manifestations. Ayurveda provides treatments for various diseases using natural plant-based remedies such as Kadamba, which was shown to reduce symptoms and improve lipid profiles.

9) Narasimha (Narasingha, Nara-simha):
V. Narasimha is one of the authors of the study and serves as an Assistant Professor in the Department of Dravyaguna at Dr. B.R.K.R. Govt. Ayurvedic College, Hyderabad, India. He contributed to the research on the efficacy of Kadamba in treating Medoroga.

10) Kshudra (Ksudra):
[see source text or glossary: Kshudra]

11) Rasa (Rasha):
Rasa Panchakas refers to the five tastes in Ayurveda, which determine the medicinal properties of herbs. Kadamba has Kashaya (astringent) and Tikta (bitter) Rasas. These tastes contribute to its therapeutic effects in managing diseases like Medoroga by balancing doshas and improving metabolism.

12) Gana:
In Ayurveda, Gana refers to a group of medicinal plants categorized based on their similar properties. Kadamba is mentioned in the 'Nyagrodadi gana' and 'Rodradi gana' in Sushruta Samhita. These categories highlight its medicinal properties, such as its effectiveness in treating Medoroga.

13) Pipasa:
Pipasa Atiyoga indicates excessive thirst, a symptom of Medoroga or hyperlipidemia. The study measured the reduction of Pipasa in patients treated with Kadamba, showing significant decreases, which indicates the efficacy of Kadamba in managing this condition.

14) Kapha:
Kapha is one of the three doshas in Ayurveda, associated with qualities like cold and heaviness. Kadamba has Kapha-hara (Kapha-reducing) properties which make it effective in treating conditions caused by Kapha imbalance, such as Medoroga (hyperlipidemia).

15) Tikta:
Tikta is the bitter taste, one of the Rasa Panchakas in Ayurveda. Kadamba's Tikta Rasa contributes to its medicinal properties, such as Ama pachana (tridoshic balancing) and Medohara (fat-reducing). This makes it effective in treating Medoroga or hyperlipidemia.

16) Angashaithilya (Angasaithilya, Anga-shaithilya):
[see source text or glossary: Anga-saithilya]

17) Sutrasthana (Sutra-sthana):
[see source text or glossary: Sutra-sthana]

18) Angagaurava (Anga-gaurava):
Angagaurava translates to heaviness in the body, a symptom of Medoroga. Relief from Angagaurava was one of the subjective parameters assessed in the study to evaluate the efficacy of Kadamba treatment, showing significant improvements in patients.

19) Dravyaguna (Dravya-guna):
Dravyaguna is the branch of Ayurveda that deals with the study of medicinal properties and actions of herbs. The study was conducted by the Department of Dravyaguna at Dr. B.R.K.R. Govt. Ayurvedic College, assessing the efficacy of Kadamba in treating Medoroga.

20) Kaphaghna (Kapha-ghna):
Kaphaghna are substances that reduce Kapha dosha. Kadamba exhibits Kaphaghna properties, making it beneficial for treating Medoroga, which involves Kapha imbalance. This property helps in reducing symptoms like heaviness and excessive sleep.

21) Vishaghna (Visaghna, Visha-ghna):
Vishaghna are substances with anti-toxic properties. Kadamba possesses Vishaghna karma, although not the study's primary focus. Its inclusion in the anti-toxic category underscores its holistic medicinal potential.

22) Nighantu (Nighamtu):
Nighantu are ancient Ayurvedic texts listing medicinal plants and their uses. Kadamba is mentioned in Nighantu like Raja Nighantu and Bhavaprakasha, which catalog its therapeutic properties, including its use in treating Medoroga or hyperlipidemia.

23) Atimatra:
[see source text or glossary: Atimatra]

24) Yoniroga (Yoni-roga):
Yoniroga refers to gynecological disorders in Ayurveda. Kadamba is mentioned as a treatment for Yoniroga. While not the focus of this study on Medoroga, its mention highlights Kadamba's broad therapeutic applications in various health conditions.

25) Prameha:
Prameha refers to a group of urinary disorders, including diabetes, in Ayurveda. Kadamba is indicated for Prameha due to its therapeutic properties. The study explores its efficacy in treating Medoroga, reflecting its versatility in managing metabolic disorders.

26) Atiyoga:
[see source text or glossary: Atiyoga]

27) Kashaya (Kasaya):
Kashaya is the astringent taste, which is one of the Rasa Panchakas in Ayurveda. Kadamba has Kashaya rasa, contributing to its Lekhana (scraping) property, which is effective in reducing excess fat and treating Medoroga or hyperlipidemia.

28) Sthana:
[see source text or glossary: Sthana]

29) ³Õ²¹°ùṇy²¹ (Varnya):
Varnya refers to substances that enhance skin complexion. Kadamba is mentioned to have Varnya properties among its multiple benefits. Although not directly related to Medoroga, Varnya highlights its broad-spectrum medicinal value.

30) Vipaka:
Vipaka refers to the post-digestive effects of a substance. Kadamba has Katu Vipaka, which helps balance Kapha and Meda (fat), aiding its effectiveness in treating Medoroga by optimizing metabolism and reducing lipid levels.

31) Sutra:
[see source text or glossary: Sutra]

32) Karma (Karman):
Karma in Ayurveda refers to the therapeutic actions of a substance. Kadamba has several karmas, including Kaphaghna (reducing Kapha) and Medohara (reducing fat), making it effective in treating diseases like Medoroga or hyperlipidemia.

33) Asthi (Ashthi):
[see source text or glossary: Asthi]

34) India:
India is the country where the study was conducted, specifically at Dr. B.R.K.R. Govt. Ayurvedic College in Hyderabad. Ayurveda is widely practiced in India, and the research contributes to the traditional Indian medical knowledge on treating Medoroga.

35) Kshudh (Ksut, Kshut, Kshud, Ksud, Ksudh):
[see source text or glossary: Ksut]

36) Katu:
Katu represents the pungent taste in Ayurveda, which involves post-digestive effects. Kadamba's Katu Vipaka helps in Kapha and Medo (fat) reduction. This property is essential for treating Medoroga or hyperlipidemia by optimizing metabolic functions.

37) Food:
Food habits are linked to the prevalence of Medoroga, or hyperlipidemia. Sedentary lifestyles and unhealthy food choices contribute to the buildup of lipids in the blood. Ayurveda recommends dietary modifications along with medicinal treatments like Kadamba for holistic health.

38) Sushruta-samhita (Susruta-samhita):
[see source text or glossary: Sushrutasamhita]

39) Rajanighantu (Raja-nighantu, Rajan-nighantu):
Raja Nighantu is an ancient Ayurvedic lexicon listing medicinal plants and their uses. Kadamba is cited in this text for its various therapeutic properties. This research evaluates Kadamba's efficacy in treating Medoroga based on such ancient references.

40) Vijayawada (Vijayavada, Vijaya-vada):
Vijayawada is the city in Andhra Pradesh state, India. Dr. Swetha Chalamalasetty, one of the authors of the study, is from Vijayawada. The city's mention highlights the geographic diversity of contributors to Ayurvedic research.

41) Discussion:
Discussion in the study refers to analyzing the results obtained from treating patients with Kadamba for Medoroga. The discussion covers statistical analyses, symptom improvements, and the comparative efficacy of the plant's bark and leaves.

42) Depression:
[see source text or glossary: Depression]

43) Shaithilya (Saithilya):
[see source text or glossary: Saithilya]

44) Knowledge:
Knowledge of Ayurveda encompasses understanding plant properties and their therapeutic effects. The study leverages this knowledge to explore Kadamba's effectiveness in treating Medoroga, contributing to the broader scientific community's insights.

45) Medicine:
Kadamba is used as a medicine in Ayurveda to treat various diseases, including Medoroga or hyperlipidemia. Ayurvedic medicine relies on natural herbs and plant-based formulations, and Kadamba is highlighted for its multiple therapeutic properties in this study.

46) Pregnant:
Pregnant women were excluded from the study on Kadamba's efficacy in treating Medoroga. This exclusion ensures the safety of both the mother and fetus, as the effects of Kadamba in pregnant women have not been thoroughly investigated.

47) Samhita:
Samhita refers to ancient Ayurvedic texts, like Sushruta Samhita, which document medicinal knowledge. These texts mention Kadamba's use in various treatments. This study validates such traditional claims by scientifically analyzing Kadamba's effects on Medoroga.

48) Lekhana:
Lekhana refers to scraping or reducing properties in Ayurveda. Kadamba has Lekhana property, which makes it useful in treating Medoroga by reducing excess body fat and lipid levels in the blood, thus addressing hyperlipidemia effectively.

49) Samaka (Shamaka):
Samaka in Ayurveda denotes pacifying actions. Kadamba has Samaka properties that help in balancing Kapha dosha. This balance makes it effective in treating Medoroga by reducing symptoms associated with high lipid levels like heaviness and lethargy.

50) Ruksha (Ruksa):
Ruksha means dry in Ayurveda and is one of the gunas (qualities) attributed to Kadamba. This dryness helps in reducing Kapha and Meda (fat), making Kadamba effective in treating Medoroga by mitigating symptoms like excessive sleepiness and weight gain.

51) Alasya:
Alasya is lethargy or laziness, a symptom of Medoroga. The study measured the improvement in Alasya as a subjective parameter to assess the effectiveness of Kadamba in treating Medoroga. Significant reductions in Alasya were observed post-treatment.

52) Shoshana (Sosana):
Sosana refers to drying or absorption properties in Ayurveda. Kadamba's Sosana property helps in drying excess fluids, reducing Kapha and Meda (fat). This action is beneficial for treating Medoroga, which involves metabolic imbalances and high lipid levels.

53) Forest:
The forest signifies the natural habitat from which Kadamba was sourced for the study. Kadamba bark and leaves were collected from Vikarabad Forest near Hyderabad, ensuring the use of genuine, high-quality plant material for therapeutic evaluation.

54) Virya:
Virya in Ayurveda denotes the potency or strength of a medicinal substance. Kadamba has Sita Virya (cool potency), contributing to its therapeutic effects in reducing Kapha and Meda, making it effective in managing Medoroga or hyperlipidemia.

55) Ayus (Ayush):
[see source text or glossary: Ayush]

56) Hara:
Hara means to remove or reduce in Ayurveda. Kadamba has Medohara properties, meaning it reduces Meda (fat), making it effective in treating Medoroga. This action is crucial for managing symptoms like excessive weight and lipid levels.

57) Raja:
Raja Nighantu is an Ayurvedic lexicon that includes medicinal plants like Kadamba. The study referenced Raja Nighantu to assess Kadamba's properties and validate its traditional uses in treating conditions like Medoroga or hyperlipidemia.

58) Anga (Amga):
[see source text or glossary: Anga]

59) Mala:
Mala in Ayurveda refers to waste products. Kadamba's properties aim to balance Dhatus (tissues) and Mala (wastes), optimizing overall health. By treating Medoroga, Kadamba helps in the effective elimination of excess lipids considered waste in the body.

60) Sita (Shita):
Sita refers to the cool potency (Virya) in Ayurvedic terms. Kadamba possesses Sita Virya, which helps balance Pitta and Kapha doshas. This property aids in effectively treating Medoroga by mitigating symptoms related to metabolic and lipid imbalances.

61) Guna:
Guna denotes the qualities or attributes of a substance in Ayurveda. Kadamba has various gunas like Ruksha (dry) and Sita (cool), contributing to its therapeutic efficacy in treating Medoroga by reducing excess Kapha and Meda (fat).

62) Tree:
Kadamba is a tree revered in Ayurveda for its medicinal properties. The study utilized bark and leaves from this tree to treat Medoroga. The results demonstrated the tree's potential to manage hyperlipidemia effectively, highlighting its medicinal value.

63) Diet:
Diet plays a crucial role in managing Medoroga or hyperlipidemia. The study emphasizes the importance of dietary habits, alongside using Kadamba, to treat lipid imbalances. Proper diet and lifestyle changes are essential in Ayurveda to complement medicinal treatments.

64) Worm:
The Kadamba bark and leaves used in the study were free from any worm infection, ensuring the purity and quality of the medicinal material. This is crucial for accurately assessing the plant's therapeutic efficacy in treating Medoroga.

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Discover the significance of concepts within the article: �Comparative study of kadamba bark and leaf in medoroga treatment.�. Further sources in the context of Science might help you critically compare this page with similair documents:

Dosha, Ayurveda, Medoroga, ³Õ²¹°ùṇy²¹, Kaphaghna, Atinidra, Shitavirya, Statistical analysis, Ayurvedic College, Comparative clinical study, Hyperlipidemia, Research article, Cardinal symptom, Medohara, Pipasa-atiyoga, Kshudra Swasa, NCEP Guidelines.

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