"Dashamoola's Shothahara effects as an anti-inflammatory: A review"
Journal name: Ayushdhara
Original article title: Shothahara activities of dashamoola dravyas as an anti inflammatory formulation with special reference to charak- a review
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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*Gopal C Nanda
Assistant Director and Incharge (Scientist –IV), Regional Ayurveda Research Institute for Eye Diseases, Lucknow, Uttar Pradesh
R K Tiwari
Research Officer (Pharmacognosy), Regional Ayurveda Research Institute for Eye Diseases, Lucknow, Uttar Pradesh
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: Shothahara activities of dashamoola dravyas as an anti inflammatory formulation with special reference to charak- a review
Year: 2016
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Introduction
The article presents a review of the anti-inflammatory and analgesic properties of Dashamoola dravyas, a traditional Ayurvedic formulation consisting of ten medicinal herbs. The authors, Gopal C. Nanda and R.K. Tiwari, explore the historical context of Dashamoola, as referenced in key Ayurvedic texts like Charak Samhita, which details various herbal combinations intended for specific health conditions. Dashamoola's applications include alleviating pain and swelling associated with arthritis, fever, and other inflammatory disorders, thus establishing it as a significant component in Ayurvedic therapeutic practices.
Role of Individual Herbs in Dashamoola: Aegle Marmelos
One of the key ingredients in Dashamoola is Aegle marmelos, commonly known as the wood apple. This herb is noted for its broad medicinal applications, particularly its analgesic and anti-inflammatory effects. Studies have shown that methanol extracts from A. marmelos leaves alleviate pain in experimental models, and its unripe fruit pulp demonstrates reduced inflammation in animal studies. Furthermore, the decoction of A. marmelos roots has been traditionally associated with treating various ailments, including fever and cardiac distress. The evidence suggests that this herb plays a critical role in the efficacy of Dashamoola as an anti-inflammatory formulation.
Immunomodulatory Effects: Gmelina Arborea
Another significant component of Dashamoola is Gmelina arborea, which is recognized for its immunomodulatory properties alongside analgesic and anti-inflammatory activities. The roots of Gmelina arborea possess various therapeutic benefits and are frequently utilized in Ayurvedic practices to treat conditions like gout, headache, and rheumatism. Research indicates that extracts of the bark exhibit significant anti-inflammatory effects compared to established anti-inflammatory drugs, such as diclofenac sodium. This highlights G. arborea's potential as a powerful natural agent that contributes to the overall effects of Dashamoola, enhancing its clinical applications in modern herbal medicine.
Conclusion
The review concludes that Dashamoola serves as a potent anti-inflammatory and analgesic formulation well-documented in Ayurvedic literature. Each herb included in Dashamoola contributes its unique properties, validating its traditional use in treating inflammation and pain. While further research is warranted to explore its systematic effects in humans, the findings affirm Dashamoola's status as a safe and effective formulation in complementary medicine. The recognition of both scientific and traditional support suggests a promising future for Dashamoola in healthcare, emphasizing the need for continued study into its comprehensive benefits and mechanisms of action.
FAQ section (important questions/answers):
What is Dashamoola and its significance in Ayurveda?
Dashamoola is a group of ten medicinal plants used in Ayurveda, primarily for its anti-inflammatory and analgesic properties. It is known for treating various conditions like arthritis, pyrexia, and abdominal pain, highlighting its role in holistic Ayurvedic treatments.
How does Dashamoola function as an anti-inflammatory formulation?
Dashamoola exerts anti-inflammatory effects through its combined ingredients, each contributing unique healing properties. Research indicates it has comparable effects to standard anti-inflammatory drugs like aspirin, and it may serve various roles in enhancing efficacy through synergistic action.
What are some individual plants included in Dashamoola?
The Dashamoola formulation includes ten plants such as Aegle marmelos, Gmelina arborea, and Oroxylum indicum. Each plant offers distinct medicinal benefits, contributing to the overall anti-inflammatory and analgesic effects of the formulation.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for �"Dashamoola's Shothahara effects as an anti-inflammatory: A review"�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Inflammation:
Inflammation is a condition where parts of the body become red, swollen, hot, and often painful, often as a reaction to injury or infection. In the context of Dashamoola, it is used to alleviate inflammation as shown by its anti-inflammatory activities in various studies.
2) Pain:
Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. Dashamoola and its components are documented to have analgesic effects, providing relief from pain, particularly in conditions like arthritis and other inflammatory diseases.
3) India:
India is a country in South Asia where many of the plants used in Dashamoola are found and cultivated, including regions like the Himalayas, Gujarat, Maharashtra, and Karnataka.
4) Family:
In botanical terms, 'family' refers to a group of related plants. For example, Aegle marmelos belongs to the Rutaceae family, while Gmelina arborea belongs to the Verbenaceae family.
5) Fever:
Fever is a rise in body temperature often due to infection or inflammation. Dashamoola and its components, such as Aegle marmelos, are used to treat fevers as part of their medicinal properties.
6) Oroxylum indicum:
Oroxylum indicum is a deciduous tree whose root bark is used for its analgesic and anti-inflammatory properties. It is one of the ingredients in the Dashamoola group.
7) Ayurveda (Ayus-veda):
Ayurveda is an ancient system of medicine from India that uses natural plants and herbs for healing. Dashamoola is an Ayurvedic formulation used for its anti-inflammatory and analgesic properties.
8) Animal:
Animal models are used in scientific studies to evaluate the efficacy of Dashamoola and its components. For example, analgesic and anti-inflammatory activities were tested in mice and rats.
9) Drug:
In the context of the text, 'drug' refers to medicinal substances. Dashamoola is considered an Ayurvedic drug utilized for its analgesic and anti-inflammatory properties.
10) Stereospermum suaveolens:
Stereospermum suaveolens is a tree whose ethanol extract of the stem bark shows potent analgesic and antipyretic activities. It is one of the ten roots included in Dashamoola.
11) Flavonoid:
[see source text or glossary: Flavonoid]
12) Disease:
Disease refers to a disorder of structure or function in a human, animal, or plant. Dashamoola’s components are used to treat a variety of diseases, including arthritis and respiratory conditions.
13) Bitter:
Bitter is a taste characteristic found in many of the plants used pharmaceutically. For instance, the root bark of Oroxylum indicum is described as acrid and bitter.
14) Edema (Oedema):
Oedema is swelling caused by excess fluid trapped in the body's tissues. Dashamoola is used in Ayurveda for its anti-oedematous effects.
15) Premna integrifolia:
Premna integrifolia, also known as Agnimantha, is one of the Dashamoola herbs. Its extracts have analgesic and anti-inflammatory activities.
16) Desmodium gangeticum:
Desmodium gangeticum is one of the plants in the Dashamoola group. It shows anti-inflammatory and analgesic effects in various pharmacological studies.
17) Gambhari:
Gambhari, or Gmelina arborea, is a component of Dashamoola known for its rejuvinative and anti-inflammatory properties.
18) Swelling:
Swelling is another term for oedema, which Dashamoola helps to alleviate thanks to its anti-inflammatory properties.
19) Nanda (Namda):
Gopal C Nanda is one of the authors of the study on the anti-inflammatory formulation Dashamoola, focusing on its effects as per Charaka Samhita.
20) Vata:
Vata is one of the three doshas in Ayurveda. Dashamoola is particularly effective in alleviating Vata-related disorders such as inflammation and pain.
21) Tree:
Tree refers to the growth form of some of the plants used in Dashamoola, such as Gmelina arborea, Oroxylum indicum, and Stereospermum suaveolens.
22) Solanum xanthocarpum:
Solanum xanthocarpum is a spiny herb used in Dashamoola. It has proven anti-inflammatory activities and is used in treating respiratory conditions.
23) Solanum indicum:
Solanum indicum, another component of Dashamoola, possesses significant analgesic, antipyretic, and anti-inflammatory activities.
24) Tribulus terrestris:
Tribulus terrestris is used in Dashamoola for its analgesic and anti-inflammatory properties and is commonly found throughout India.
25) Gmelina arborea:
Gmelina arborea, also known as Gambhari, is one of the ten roots of Dashamoola, known for its anti-inflammatory and analgesic activities.
26) Prishniparni (Prsniparni, Prishni-parni):
Prishniparni, or Uraria picta, is included in Dashamoola and has shown significant anti-inflammatory and analgesic effects.
27) Agnimantha (Agni-mantha, Agnimamtha):
Agnimantha, or Premna integrifolia, is one of the herbs in Dashamoola and is noted for its benefits in treating inflammation and pain.
28) Shothahara (Sothahara, Shotha-hara):
Sothahara refers to the action of reducing inflammation. Dashamoola is known for its Sothahara activities.
29) Leucoderma:
[see source text or glossary: Leucoderma]
30) Kantakari (Kamtakari):
Kantakari, or Solanum xanthocarpum, is part of Dashamoola. It has significant anti-inflammatory and analgesic activities.
31) Shyonaka (Syonaka):
Shyonaka, or Oroxylum indicum, is one of the ten roots in Dashamoola, noted for its analgesic and anti-inflammatory properties.
32) Gokshura (Goksura, Go-kshura):
Gokshura, or Tribulus terrestris, is one of the roots in Dashamoola. It has medicinal properties including analgesic and anti-inflammatory effects.
33) Vomiting:
Vomiting is a symptom that Dashamoola can help alleviate, as some of its components like Oroxylum indicum are known for their anti-emetic properties.
34) Samhita:
Samhita refers to classical Ayurveda texts. Dashamoola is mentioned in Charaka Samhita and Sushruta Samhita as a potent formulation for inflammation and pain.
35) Dravya:
Dravya refers to substances or herbs. Dashamoola Dravyas implies the group of ten herbs used in the Dashamoola formulation.
36) Patala:
Patala, or Stereospermum suaveolens, is one of the ten roots in Dashamoola known for its analgesic and anti-inflammatory properties.
37) Bilva (Vilva):
Bilva or Aegle marmelos is one of the herbs in Dashamoola. It shows significant analgesic and anti-inflammatory activities in various studies.
38) Pharmacological:
Pharmacological relates to the study of drugs and their effects. The text reviews the pharmacological activities of the herbs in Dashamoola.
39) Aegle marmelos:
Aegle marmelos, also known as Bilva, is a component of Dashamoola with significant analgesic and anti-inflammatory properties.
40) Shalparni (Salparni):
Shalparni, or Desmodium gangeticum, is one of the herbs in Dashamoola known for its anti-inflammatory and analgesic properties.
41) Arishta (Arista):
Arishta refers to a fermented decoction used in Ayurveda. Dashamoola can be administered in this form for its medicinal benefits.
42) Gujarat:
Gujarat is an Indian state where some of the Dashamoola plants like Premna integrifolia are found.
43) Lucknow:
Lucknow is the location of RARIED, where Gopal C Nanda, one of the study's authors, is based.
44) Kashaya (Kasaya):
Kashaya refers to a decoction. Dashamoola is often used in this form in various Ayurvedic treatments.
45) Forest:
Forest habitats are crucial for the plants used in Dashamoola, including places like Maharashtra, Himalayas, and the Western Ghats.
46) Indian:
Indian refers to the origin of many herbs used in Dashamoola and the Ayurveda tradition where this formulation is grounded.
47) Blood:
Blood detoxification is one of the medicinal uses of Stereospermum suaveolens, a component of Dashamoola.
48) Cina:
China is mentioned as part of the native range of Oroxylum indicum, one of the ten roots in Dashamoola.
49) Worm:
[see source text or glossary: Worm]
50) Burning sensation:
Burning sensation is one of the symptoms relieved by Solanum xanthocarpum, which is part of the Dashamoola formulation.
51) Central India:
Central India is a region where Stereospermum suaveolens and other Dashamoola herbs are indigenous.
52) Sushruta-samhita (Susruta-samhita):
Sushruta Samhita is a classic Ayurvedic text that mentions Dashamoola as an effective treatment for various ailments.
53) Antibiotic (Antibacterial):
[see source text or glossary: Anti-bacterial]
54) Maharashtra (Maharastra, Maha-rashtra):
Maharashtra is an Indian state where several Dashamoola plants like Premna integrifolia are found.
55) Perception:
Pain perception is a key concept in studying the analgesic effects of Dashamoola in various pharmacological tests on animals.
56) Karnataka:
Karnataka is an Indian state where plants like Premna integrifolia, used in Dashamoola, are found.
57) Rajasthan:
Rajasthan is an Indian state where plants like Tribulus terrestris, part of Dashamoola, are commonly found.
58) Kashmari (Kasmari):
Kashmari, or Gambhari (Gmelina arborea), is a component of Dashamoola with rejuvinative and anti-inflammatory properties.
59) Rasayana (Rasa-ayana):
Rasayana is a rejuvenative therapy in Ayurveda. Gambhari (Gmelina arborea) in Dashamoola has Rasayana properties.
60) Vatahara (Vata-ahara):
Vatahara refers to the action of alleviating Vata disorders. Dashamoola is effective in treating conditions related to Vata imbalance.
61) Himalaya (Hima-alaya):
The Himalaya region is mentioned as part of the native range of Oroxylum indicum, which is part of Dashamoola.
62) Medicine:
Medicine refers to the use of plants in Dashamoola for treating various ailments such as inflammation, pain, and fever.
63) Vrishya (Vrsya):
Vrishya means aphrodisiac in Ayurveda. Gambhari, a component of Dashamoola, is known for its Vrishya activity.
64) Habitat:
Habitat refers to the natural environment where plants used in Dashamoola grow, such as forests in India and the Himalayas.
65) Shotha (Sotha):
Shotha in Ayurveda denotes inflammation and oedema, conditions against which Dashamoola is effective.
66) Bombay:
Bombay, now known as Mumbai, is referenced as a location near which plants like Premna integrifolia can be found.
67) Bengal (Bemgal):
Bengal is mentioned as a region where plants like Premna integrifolia, used in Dashamoola, are found.
68) Medhya:
Medhya means memory enhancer in Ayurveda. Gambhari, a component of Dashamoola, is known for its Medhya properties.
69) Cancer:
[see source text or glossary: Cancer]
70) Nature:
Nature refers to the inherent qualities of Dashamoola ingredients, such as their anti-inflammatory and analgesic effects.
71) Powder:
Powder form is one of the ways medicinal plants like Solanum xanthocarpum can be used in treatments.
72) Cotton:
[see source text or glossary: Cotton]
73) Desire:
Sexual desire is increased by some of the Dashamoola plants like Tribulus terrestris and Gambhari, which have aphrodisiac properties.
74) Kapha:
Kapha is one of the three doshas in Ayurveda. Dashamoola helps in balancing Vata and Kapha doshas.
75) Kalka:
Kalka refers to paste in Ayurveda, one of the forms in which Dashamoola can be used.
[Note: The above list is limited to 75. Total glossary definitions available: 79]
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