RCT of Vijayadi Vati for Kashtartava (Primary Dysmenorrhea)
Journal name: Ayushdhara
Original article title: A Randomized Controlled Clinical Trial of Vijayadi - Vati on Kashtartava (Primary Dysmenorrhoea)
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Sharma Upasana
Lecturer, Department of Prasuti Tantra Stri Roga, NIA, Jaipur, Rajasthan, India
Sharma Sushila
Supervisor, Retired Professor and HOD, Department of Prasuti Tantra Stri Roga, NIA, Jaipur, Rajasthan, India
B. Pushpalatha
Professor, Department of Prasuti Tantra Stri Roga, NIA, Jaipur, Rajasthan, India
Dave H. Hetal
Associate Professor, Department of Prasuti Tantra Stri Roga, NIA, Jaipur, Rajasthan, India
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: A Randomized Controlled Clinical Trial of Vijayadi - Vati on Kashtartava (Primary Dysmenorrhoea)
Year: 2022 | Doi: 10.47070/ayushdhara.v9i6.1105
Copyright (license): CC BY-NC-SA 4.0
Download the PDF file of the original publication
Summary of article contents:
Introduction
Primary dysmenorrhea, characterized by painful menstruation without identifiable pelvic pathology, is a widespread issue among adolescent girls, with prevalence rates in India ranging from 50% to 87.8%. This clinical trial aimed to evaluate the effectiveness of two Ayurvedic formulations, Vijayadi Vati and Ashwagandha Choorna, in managing the symptoms of primary dysmenorrhea, referred to as Kashtartava in Ayurveda. Conducted at the National Institute of Ayurveda, Jaipur, the study involved 30 patients aged between 16 and 30 years, who were randomly assigned to one of two treatment groups. The trial assessed the relief achieved by these formulations over two menstrual cycles, focusing on various symptoms related to dysmenorrhea.
The Role of Vata Dosha in Dysmenorrhea
In Ayurveda, dysmenorrhea is largely associated with the vitiation of Vata dosha, which is considered a primary factor causing menstrual pain. The disruption of Apana Vayu, which governs the expulsion of menstrual blood, is thought to contribute significantly to the occurrence of painful menstruation. This connection implies that effective treatments should focus on pacifying vitiated Vata. The clinical trial demonstrated that Vijayadi Vati exhibited notable anti-inflammatory, analgesic, and anti-prostaglandin effects, which significantly alleviated pain and enhanced the quality of life for participants. The findings suggest that targeting Vata dosha through formulations like Vijayadi Vati can be a beneficial approach in treating primary dysmenorrhea.
Efficacy of Ayurvedic Treatments
The results indicated that participants in Group A, who received Vijayadi Vati, experienced a higher percentage of relief from symptoms compared to those in Group B, who were treated with Ashwagandha Choorna. Specifically, Group A reported an average relief of 67.78%, while Group B noted a relief of 60.44%. Key symptomatic improvements were recorded for pain intensity, duration, and associated symptoms, demonstrating the efficacy of Ayurvedic approaches in managing primary dysmenorrhea. The trial also recorded no adverse drug reactions in any participants, suggesting the safety and tolerability of the Ayurvedic treatments.
Conclusion
This clinical trial reveals that Ayurveda offers effective and safe treatments for primary dysmenorrhea. By focusing on the pacification of Vata dosha, particularly through formulations like Vijayadi Vati and Ashwagandha Choorna, significant improvements in symptoms can be achieved. As dysmenorrhea has considerable impacts on daily activities, finding effective management strategies is crucial. The study highlights the potential of integrating traditional Ayurvedic medicine with modern clinical practices for treating menstrual disorders, and future research is recommended to further explore these findings and validate the results in larger populations.
FAQ section (important questions/answers):
What is the focus of the study on Vijayadi Vati?
The study investigates the efficacy of Vijayadi Vati in treating primary dysmenorrhea (Kashtartava), focusing on its properties like anti-inflammatory and rejuvenating effects, comparing its results to Ashwagandha choorna.
How many patients participated in the clinical trial?
A total of 36 patients diagnosed with primary dysmenorrhea were selected, out of which 30 completed the treatment course in the trial conducted at the National Institute of Ayurveda, Jaipur.
What were the main findings regarding the drug treatments?
The results indicated that Vijayadi Vati showed a significant improvement in pain intensity and overall relief, achieving an average percentage of relief of 67.78%, compared to 60.44% for Ashwagandha choorna.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “RCT of Vijayadi Vati for Kashtartava (Primary Dysmenorrhea)�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Pain:
Pain refers to the primary symptom of dysmenorrhoea, including Kashtartava, where females suffer from it during menstruation. The study specifically looks at the intensity, duration, and nature of pain as key clinical parameters.
2) Vata:
Vata dosha is a primary element in Ayurveda, and its vitiation is responsible for the pain and symptoms associated with Kashtartava (primary dysmenorrhea). The treatment focuses on pacifying Vata to alleviate symptoms.
3) Drug:
Drug interventions in the study include Ayurveda formulations such as Vijayadi-vati and Ashwagandha choorna. These drugs are intended to relieve symptoms of Kashtartava through their specific properties.
4) Vijayadi (Vijaya-adi):
Vijayadi refers to a component in the Vijayadi-vati formulation. This drug is selected for its anti-inflammatory, analgesic, and anti-prostaglandin properties, which help in reducing the pain of primary dysmenorrhoea.
5) Dysmenorrhea (Dysmenorrhoea):
[see source text or glossary: Dysmenorrhea]
6) Kashtartava (Kastartava, Kashta-artava):
Kashtartava is the Ayurveda term for primary dysmenorrhoea. The study explores Ayurvedic formulations aimed at managing this condition, characterized by painful menstruation without identifiable pelvic pathology.
7) Vati:
Vati indicates a tablet form of Ayurvedic medicine. In this study, Vijayadi-vati is one such formulation used to treat Kashtartava by leveraging its pain and inflammation-reducing properties.
8) Disease:
Disease in this context refers to gynecological disorders like Kashtartava (primary dysmenorrhoea). Although not life-threatening, it significantly affects the quality of life and daily activities of affected females.
9) Ashvagandha (Asvagandha, Ashwagandha, Ashvagamdha, Ashva-gandha):
Ashwagandha, used in the form of Ashwagandha choorna, is another Ayurvedic remedy assessed in the study. It is noted for its anti-inflammatory, rejuvenating, and Vata-pacifying properties.
10) Ayurveda (Ayus-veda):
Ayurveda is the ancient Indian medical system which informs this study. It emphasizes balancing bodily doshas (like Vata) to treat diseases, here primarily focusing on primary dysmenorrhoea.
11) Vitiation (Vitiated):
Vitiation refers to the imbalance or disturbance of a dosha. In this study, the vitiation of Vata dosha is highlighted as the principal cause of pain in Kashtartava.
12) Blood:
Blood is critical in the context of menstruation. Disruption in the normal flow of menstrual blood is often central to conditions like Kashtartava, which this study aims to address.
13) Menstrual blood:
Menstrual blood is the focus of symptoms and treatment in primary dysmenorrhoea. Ayurveda attributes its flow to the balanced action of Apana Vata, which is targeted in this study.
14) Dosha (Dosa):
Dosha refers to the fundamental bodily bio-elements in Ayurveda (Vata, Pitta, Kapha). Imbalances in these doshas, especially Vata, are treated to alleviate primary dysmenorrhoea symptoms in this study.
15) Nature:
[see source text or glossary: Nature]
16) Sharman (Sarma, Sharma, Sarman):
[see source text or glossary: Sharma]
17) Vatadosha (Vatadosa, Vata-dosha):
Vata-dosha is highlighted as the primary dosha involved in the pathogenesis of Kashtartava. The study's treatments focus on pacifying Vata to mitigate symptoms of dysmenorrhoea.
18) Ushna (Usna):
Ushna, meaning hot potency, is a quality attributed to the studied Ayurvedic drugs like Vijayadi-vati and Ashwagandha choorna that help in pacifying Vata and relieving pain.
19) Vayu:
Vayu, another term for Vata or wind, is viewed as the cause of pain in Ayurveda. Controlling Vayu is essential for managing primary dysmenorrhoea, which is achieved through specific Ayurvedic treatments.
20) Prabhava:
Prabhava refers to the inherent special efficacy of a substance beyond its basic physical properties. Herbs used in this study have multiple Prabhavas to target aspects of Vata vitiation and pain.
21) Vomiting:
Vomiting is identified as one of the associated symptoms of primary dysmenorrhoea evaluated in both groups; treatments like Vijayadi-vati have anti-emetic properties to counteract this.
22) Upasana:
[see source text or glossary: Upasana]
23) Nausea:
Nausea is another associated symptom of primary dysmenorrhoea discussed. The study finds that anti-emetic properties of Vijayadi-vati significantly reduce nausea alongside alleviating pain.
24) Guna:
Guna refers to the inherent properties of a substance. In this study, the Guna of drugs like Vijayadi-vati is crucial for their efficacy against primary dysmenorrhoea symptoms.
25) Fainting (Fainted):
Fainting is a less common but noted symptom of primary dysmenorrhoea. Both Ayurvedic formulations were shown to moderately alleviate this symptom among the studied patients.
26) Prasuti:
Prasuti refers to pregnancy and childbirth in Ayurveda. The Department of Prasuti Tantra at NIA, Jaipur, is where this study's cases were selected and treated, focusing on gynecological health.
27) Vipaka:
Vipaka refers to the post-digestive effect of a substance. The drugs in the study, such as Vijayadi-vati, exhibit Katu Vipaka (pungent post-digestive effect), significant in managing Vata-related disorders.
28) Jaipur:
Jaipur is the location of the National Institute of Ayurveda where this study was conducted. It provides the context and setting for the clinical trial assessing Ayurvedic treatments.
29) Kapha:
Kapha is one of the three doshas in Ayurveda. While Vata is the primary dosha vitiated in primary dysmenorrhoea, other doshas like Kapha may be involved as associates, influencing symptoms.
30) Apana:
Apana denotes the downward moving wind and is a sub-type of Vata. Its dysregulation is crucial in the context of primary dysmenorrhoea (Kashtartava), targeted by the drugs in this study.
31) Sweating (Sweat):
Sweating, or excessive perspiration, is another symptom managed in primary dysmenorrhoea. Its regulation is part of the therapeutic goal of the Ayurvedic treatments studied.
32) Roga:
Roga means disease in Ayurveda. Prasuti and Stree Roga (Gynecology) is the specialty area dealing with conditions like Kashtartava, addressed in this clinical study using Ayurvedic formulations.
33) Katu:
Katu means pungent and refers to both taste and vipaka. Katu vipaka of Vijayadi-vati is significant in the treatment of primary dysmenorrhoea as it helps to alleviate Vata vitiation.
34) Medicine:
Medicine in this study pertains to Ayurvedic therapies like Vijayadi-vati and Ashwagandha choorna, explored for their efficacy in treating primary dysmenorrhoea by balancing doshas.
35) Vyana:
[see source text or glossary: Vyana]
36) Vyanavata (Vyana-vata):
Vyana-vata is a sub-type of Vata responsible for movements and activities of the body. Its coordination with Apana Vata is crucial in menstrual activities, and its dysregulation causes pain in dysmenorrhoea.
37) Apanavayu (Apana-vayu):
[see source text or glossary: Apanavayu]
38) Apanavata (Apana-vata):
Apanavata refers to the sub-type of Vata responsible for downward movements, including menstruation. Its dysregulation can cause painful menstruation and is targeted in the treatments studied.
39) Dravyaguna (Dravya-guna):
Dravyaguna refers to the pharmacological attributes of herbal drugs used in Ayurveda. The study focuses on Dravyaguna of Vijayadi-vati and Ashwagandha choorna in managing Kashtartava.
40) Discussion:
[see source text or glossary: Discussion]
41) Anulomana:
Anulomana refers to the action of restoring normal flow, particularly of Vata. The study details how the selected treatments facilitate Anulomana of Apana Vata to manage dysmenorrhea symptoms.
42) Tikshna (Tiksna):
[see source text or glossary: Tiksna]
43) Tantra (Tamtra, Tantrism):
[see source text or glossary: Tantra]
44) Kumari:
Kumari, another name for Aloe vera, is an ingredient in Vijayadi-vati. It has anti-spasmodic properties contributing to the treatment of the painful spasms in primary dysmenorrhoea.
45) Virya:
Virya refers to the potency of a substance. The drugs used in the study, such as Vijayadi-vati, have Ushna Virya (hot potency), making them effective in pacifying Vata dosha and alleviating pain.
46) India:
[see source text or glossary: India]
47) Burning sensation:
[see source text or glossary: Burning sensation]
48) Margavarodha (Marga-avarodha):
Margavarodha refers to the obstruction of pathways, a concept crucial in Ayurveda. Primary dysmenorrhoea includes Vata obstruction, alleviated by the properties of the studied drugs.
49) Malnutrition:
[see source text or glossary: Malnutrition]
50) Garbhashaya (Garbhasaya, Garbha-ashaya):
Garbhashaya refers to the uterus. Conditions affecting the uterus, like primary dysmenorrhoea (Kashtartava), are addressed by the targeted Ayurvedic treatments in this study.
51) Dhatukshaya (Dhatuksaya, Dhatu-kshaya):
Dhatukshaya denotes the depletion of bodily tissues, a contributing factor in Vata vitiation. Dhatukshaya leads to symptoms like those seen in primary dysmenorrhoea, addressed by the study's treatments.
52) Bhaishajya (Bhaisajya):
Bhaishajya Ratnavali is an Ayurvedic text that provides formulations for treating diseases. Vijayadi-vati specifically references this text for treating Kashtartava, demonstrating its traditional basis.
53) Shothahara (Sothahara, Shotha-hara):
Shothahara means anti-inflammatory. This property is critical in the study’s drugs, which help in reducing inflammation and alleviating pain associated with primary dysmenorrhoea.
54) Samprapti:
Samprapti refers to pathogenesis in Ayurveda. Understanding the Samprapti of primary dysmenorrhoea is key in managing it through Ayurvedic formulations that target Vata vitiation and inflammation.
55) Vyanavayu (Vyana-vayu):
[see source text or glossary: Vyanavayu]
56) Rajasthan:
[see source text or glossary: Rajasthan]
57) Striroga (Stri-roga):
Stri-roga means gynecological disorders in Ayurveda. The Department of Prasuti Tantra and Stree Roga at NIA, Jaipur, specializes in treating these conditions, like primary dysmenorrhoea, studied here.
58) Stiffness:
Stiffness is one of the symptomatic manifestations of Vata vitiation described in Ayurveda. It accompanies conditions like Kashtartava and is reduced by the studied Ayurvedic treatments.
59) Udavarta:
Udavarta indicates reverse peristalsis or upward movement of Vata, a cause of pain during menstruation. Treatments focus on counteracting Udavarta by normalizing Vata flow.
60) Samanya:
Samanya refers to the principle of similarity in Ayurveda. In this study, the principle is applied to understanding how hot potencies (Ushna veerya) in medications help in managing menstrual pain.
61) Samaka (Shamaka):
Shamaka means pacifying. The treatments used in the study have Vata-shamaka (Vata-pacifying) properties, crucial for alleviating the pain and symptoms of primary dysmenorrhoea.
62) Dravya:
Dravya means substance or drug. The study involves the evaluation of specific dravyas like Vijayadi-vati and Ashwagandha choorna for their efficacy in treating Kashtartava.
63) Dushya (Dusya):
Dushya refers to the bodily elements affected by dosha imbalance. In the context of Kashtartava, managing these dushyas involves balancing Vata and restoring proper menstrual function.
64) Artava:
Artava means menstrual blood. Proper management of Artava is central to treating primary dysmenorrhoea in Ayurveda, targeted by the drugs studied.
65) Vihara:
Vihara refers to lifestyle. Ayurveda treatments for primary dysmenorrhoea include recommendations for Vata-pacifying vihara, alongside the studied formulations.
66) Vataja (Vata-ja):
[see source text or glossary: Vataja]
67) Kriya:
Kriya means action or treatment. The Kriya in this study involves administering Ayurvedic drugs to manage Vata vitiation and alleviate primary dysmenorrhoea.
68) Laghu:
Laghu means lightness, a property of some drugs in Ayurveda. Laghu drugs help in alleviating Vata dosha disorders like primary dysmenorrhoea by easing bodily functions and reducing pain.
69) Tikta:
Tikta means bitter, one of the tastes (Rasa) in Ayurveda. The drugs used in the study such as Vijayadi-vati have Tikta rasa which helps in pacifying Vata and managing primary dysmenorrhoea.
70) Ahara:
Ahara means diet. Managing diet (Ahara) is an essential aspect of Ayurveda treatments for primary dysmenorrhoea, aimed at balancing Vata and overall health.
71) Balya:
Balya refers to rejuvenating and strength-giving properties. Ashwagandha choorna, used in the study, is noted for its Balya effects which support overall health and mitigate primary dysmenorrhoea symptoms.
72) Ayus (Ayush):
[see source text or glossary: Ayush]
73) Rasa (Rasha):
Rasa refers to taste and is significant in determining the action of a drug in Ayurveda. Tikta (bitter) and Katu (pungent) rasas in the drugs studied are critical for treating primary dysmenorrhoea.
74) Diet:
[see source text or glossary: Diet]
Other Science Concepts:
Discover the significance of concepts within the article: �RCT of Vijayadi Vati for Kashtartava (Primary Dysmenorrhea)�. Further sources in the context of Science might help you critically compare this page with similair documents:
Kashtartava, Statistical analysis, Clinical significance, Inclusion criteria, Exclusion criteria, Adverse reaction, Ayurvedic formulation, Clinical trial, Ethical committee approval, Pain severity, Pain intensity assessment, Symptomatic improvement, Randomized controlled study, Therapeutic outcome, Subjective parameter, Primary dysmenorrhea, Dosha involvement, Ashwagandha choorna, Vijayadi Vati, Menstrual Flow Amount.