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Analgesic activity of Nelsonia canescens (Lam.) Spreng.root in albino rats

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Journal name: AYU (Journal of Research in Ayurveda)
Original article title: Analgesic activity of Nelsonia canescens (Lam.) Spreng.root in albino rats
AYU is an internationally recognized quarterly journal dedicated to advancing research in Ayurveda. The journal covers a wide range of topics, including clinical and pharmacological research in Ayurveda's eight branches, herbal remedies, phytochemistry, and ethnomedicine.

Original source:

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Author(s):

Behzad Mohaddesi
Ravindra Dwivedi
B. K. Ashok
Hetal Aghera
Rabinarayan Acharya
V. J. Shukla


AYU (Journal of Research in Ayurveda):

(An International Quarterly Journal of Research in Ayurveda)

Full text available for: Analgesic activity of Nelsonia canescens (Lam.) Spreng.root in albino rats

Year: 2013 | Doi: 10.4103/0974-8520.119688

Copyright (license): CC BY-NC-SA 4.0


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Summary of article contents:

Present study was undertaken to evaluate analgesic activity of root of Nelsonia canescens (Lam.) Spreng, a folklore medicinal plant used as the one of the source plant of Rasna. Study was carried out at two dose levels (270 mg/kg and 540 mg/kg) in albino rats. Analgesic activity was evaluated in formalin induced paw licking, and tail flick methods whereas indomethacin and pentazocine were used as standard analgesic drugs, respectively. At both the dose levels, test drug non-significantly decreased paw licking response at both time intervals. In tail flick model, the administration of the test drug increased pain threshold response in a dose dependent manner. In therapeutically equivalent dose level, analgesic activity was observed only after 180 min while in TED ×2 treated group analgesia was observed at 30 min and lasted even up to 240 min. The results suggested that N.canescens root possess moderate analgesic activity. Keywords: Analgesic, folklore, gandhamardana hills, Nelsonia canescens, Rasna

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Discover the significance of concepts within the article: �Analgesic activity of Nelsonia canescens (Lam.) Spreng.root in albino rats�. Further sources in the context of Science might help you critically compare this page with similair documents:

Rasna, Statistically Significant, Analgesic activity, Traditional systems of medicine, Folklore medicinal plant, Institutional animal ethics committee, Dose-dependent manner, Pharmacognosist, Nelsonia canescens, Formalin induced paw licking, Tail flick test, Nociception, Indomethacin, Pentazocine, Experimental animal, Standard analgesic drug, Albino rat, Inflammatory mediator.

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