Significance of Tail flick test
The tail flick test is an experimental method used to evaluate the analgesic activity and pain sensitivity in animals, specifically by measuring the time it takes for a rat or mouse to withdraw its tail from a heat source. This test assesses the central analgesic activity by recording the latency of the tail response to thermal stimuli, thus providing insights into pain relief and the effectiveness of analgesics. The results indicate the level of nociception and the potency of pain relief measures.
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The concept of Tail flick test in scientific sources
The Tail flick test is a behavioral assessment in animals that evaluates pain sensitivity and analgesic effectiveness by measuring the response time to a heat stimulus applied to the tail.
From: World Journal of Pharmaceutical Research
(1) A reflexive pain response test where a heated stimulus is applied to a tail and the latency to withdraw it is measured, indicating analgesic activity.[1] (2) An experimental method for assessing pain response in animals by measuring the reaction time of withdrawal from a heat source.[2] (3) A method to assess the analgesic effect in which a rat's tail is exposed to heat, and the time until the animal flicks its tail away is measured.[3] (4) An antinociceptive activity assessment method, where latency to withdraw the tail from a heat source is measured to evaluate pain relief.[4] (5) The tail-flick test is a method used to determine the level of nociception and measure the analgesic efficacy of pharmacological agents by measuring the withdrawal time of an animal's tail in response to a thermal stimulus.[5]
From: AYU (Journal of Research in Ayurveda)
(1) An experimental method to measure the antinociceptive effect of analgesics by assessing the latency of tail withdrawal in rats exposed to a heat source.[6] (2) A method to measure pain sensitivity based on the time it takes for an animal to withdraw its tail from a heat source.[7] (3) A method used to evaluate the reaction time of rats to a thermal stimulus, assessing central analgesic activity.[8] (4) A behavioral test in animals to evaluate analgesic potency through the latency period before they respond to heat applied to their tail.[9] (5) An experimental procedure to measure pain sensitivity in animals by applying a heat stimulus to the tail and recording response time.[10]
From: Ancient Science of Life
(1) A method used to assess the analgesic activity by measuring the latency of the tail response when exposed to heat.[11]