Significance of Inflammatory mediator
Inflammatory mediators are biological substances that promote and regulate inflammation in the body. They include cytokines, histamine, and prostaglandins, which contribute to various health conditions such as osteoarthritis, asthma, rheumatoid arthritis, and periodontal disease. These mediators play crucial roles in the inflammatory response, affecting processes like vascular permeability and tissue damage. Research focuses on understanding these substances to develop treatment interventions, including the influence of certain medicinal plants on reducing their effects in conditions like Alzheimer's disease and chronic inflammation.
Synonyms: Cytokine, Inflammatory agent, Prostaglandin, Histamine, Platelet-activating factor, Interleukin, Tumor necrosis factor
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Inflammatory mediator in scientific sources
Inflammatory mediators are substances generated during inflammation that impact processes like vascular permeability, contribute to symptoms such as edema, and are critical in assessing nanoemulsion effectiveness in wound treatment and other bodily responses.
From: The Malaysian Journal of Medical Sciences
(1) The released inflammatory mediators and neuromodulators act on selected receptors and ion channels to generate APs, as seen in the text, which mentions specific examples like PGE2 and H+.[1] (2) These are substances that can be associated with sleep disturbances and various types of pain, potentially related to hyper-reactivity.[2] (3) Matrix metalloproteinase (MMP) is a group of these molecules, which are zinc-containing endo-proteinases, and they are responsible for accelerated atherosclerosis.[3] (4) These are produced by the KA-induced model, along with seizure, behavioral changes, and oxidative stress.[4] (5) These are substances that promote inflammation, and pulegone may act by inhibiting their production.[5]