Significance of Tumor necrosis factor
Tumor necrosis factor (TNF) is a critical cytokine involved in systemic inflammation, playing a vital role in regulating immune cells and influencing tumor dynamics. It is associated with multiple functions, including inducing cell lysis, promoting anticancer properties, and being linked to various diseases due to elevated levels. TNF's involvement extends to genetic susceptibility to diseases, interactions with other growth factors, and its significance in chronic inflammatory states, making it a key player in both immune responses and inflammation-related conditions.
Synonyms: Tumor necrosis factor-alpha, Cytokine, Tnf-alpha
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The concept of Tumor necrosis factor in scientific sources
Tumor necrosis factor (TNF) is a crucial immune regulator involved in inflammation, exhibiting cytotoxic effects on tumor cells, and its elevated levels are associated with various diseases, including diabetes.
From: The Malaysian Journal of Medical Sciences
(1) This phrase is associated with fever and serum levels during clinical paroxysms in Plasmodium vivax malaria, indicating a study of the illness.[1] (2) This is a factor that is considered a determinant of pathogenesis and disease progression, especially in the context of mycobacterial infection within the central nervous system.[2] (3) This refers to a specific pathway, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) pathway signaling, which is discussed in a publication.[3] (4) A cytokine involved in the inflammatory response which may support peripheral nerve injury recovery.[4]