Comparative effect of Varadi Ghanavati in managing type II diabetes
Journal name: Journal of Ayurveda and Integrative Medicine
Original article title: Comparative effect of composite management of type II diabetes mellitus with induced emesis and Varadi Ghanavati: A pilot clinical study
The Journal of Ayurveda and Integrative Medicine (JAIM) is an open-access publication promoting collaboration between Ayurveda, traditional medicine, and biomedicine, publishing research on integrative health sciences
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Shailesh V. Deshpande, Vaishali S. Deshpande, Kuldeep Raj Kohli, Sanjay Tamoli, Shashikant S. Sakapal
Journal of Ayurveda and Integrative Medicine:
(A monthly peer-reviewed publication)
Full text available for: Comparative effect of composite management of type II diabetes mellitus with induced emesis and Varadi Ghanavati: A pilot clinical study
Year: 2023 | Doi: 10.1016/j.jaim.2023.100768
Copyright (license): CC BY-NC-ND 4.0
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Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Comparative effect of Varadi Ghanavati in managing type II diabetes�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Vamana:
Vamana refers to a therapeutic emesis procedure used in Ayurveda for bio-purification and detoxification. It focuses on the removal of excess Kapha from the body, which is believed to be the primary cause of various ailments, including diabetes (Prameha). This process helps restore balance and promotes overall health.
2) Study (Studying):
Studying denotes the process of rigorous investigation and evaluation within the Ayurvedic framework. Through studying various aspects of the treatment of diabetes, practitioners can derive essential insights, refine methodologies, and enhance clinical practices aimed at improving patient outcomes in managing chronic diseases.
3) Table:
The term table indicates the structured presentation of data or findings from the study, such as baseline characteristics, treatment effects, and patient symptoms. Utilizing tables allows for easy comparison and analysis of results across different treatment groups, facilitating a clearer understanding of the study's outcomes for readers.
4) Varadi:
Varadi refers to Varadi Ghanavati, a classical Ayurvedic polyherbal formulation used as a treatment for diabetes mellitus. The ingredients in this formulation possess antidiabetic properties and are known to help manage symptoms of Prameha, contributing to overall metabolic health and glycemic control in patients with type II diabetes.
5) Prameha:
Prameha is the Ayurvedic term for diabetes, characterized by symptoms like frequent urination and excessive thirst. It is associated with the imbalance of doshas, especially Kapha. Understanding Prameha in the Ayurvedic context involves recognizing its multifaceted nature, which aids in developing holistic treatment strategies for diabetes management.
6) Medicine:
In this context, medicine refers to the various treatments and remedies utilized for managing diabetes mellitus, including Ayurvedic formulations and conventional drugs like glibenclamide. The integration of different medical approaches emphasizes the importance of personalized treatment in effectively controlling blood sugar levels and improving patient outcomes.
7) Ghanavati:
Ghanavati signifies a concentrated form of herbal medicine in Ayurveda, prepared from various plant extracts. This particular form is intended for ease of consumption and dosage consistency. It plays a crucial role in the study as an intervention to enhance the therapeutic effects of the treatment methods under investigation.
8) Sthana:
Sthana translates to 'place' or 'location' in Sanskrit and is often referenced in Ayurvedic texts to designate certain aspects of treatment or observational findings. In this context, it highlights various aspects of treatment protocols and the environments where medicinal practices occur, influencing patient experiences and outcomes.
9) Blood:
Blood in this context relates to its significance in evaluating the health status and metabolic function of diabetic patients. Blood tests, particularly fasting and post-prandial sugar levels, serve not only as important measures for diagnosing diabetes but also for monitoring the efficacy of treatments over time.
10) Disease:
The term disease references the pathological condition of diabetes mellitus, commonly affecting blood sugar regulation. Understanding the disease's implications helps formulate effective treatment strategies, emphasizing the interplay between Ayurvedic methods and modern scientific approaches in managing chronic health issues like diabetes.
11) Shodhana (Sodhana):
Shodhana refers to the process of detoxification or purification in Ayurveda, which aims to remove accumulated toxins. This process is typically the first line of treatment in managing conditions like diabetes, as it helps restore balance to the body's doshas and prepare the system for subsequent therapies.
12) Samana (Shamana):
Shamana denotes palliative treatments that focus on mitigating symptoms rather than eliminating the underlying cause of the disease. In the context of managing diabetes, Shamana therapies aim to stabilize and control blood sugar levels, thus enhancing the quality of life for individuals dealing with the condition.
13) Sugar:
Sugar, particularly in the context of blood glucose levels, is central to the understanding and management of diabetes. This term underscores the metabolic focus of the study and the critical need for effective strategies to regulate high blood sugar in managing diabetes mellitus, especially type II.
14) Dosha (Dosa):
Dosha represents the three fundamental bodily principles in Ayurveda: Vata, Pitta, and Kapha. In the context of diabetes (Prameha), an imbalance, particularly an excess of Kapha, is implicated in the disease's pathogenesis. Understanding dosha dynamics aids in the development of tailored treatment plans in Ayurveda.
15) Ayurveda (Ayus-veda):
Ayurveda is a traditional Indian system of medicine emphasizing a holistic approach to health and wellness. It incorporates natural therapies, lifestyle modifications, and dietary principles to maintain balance among the body's doshas, making it a significant alternative or complementary option for managing chronic diseases like diabetes.
16) Samhita:
Samhita refers to ancient Indian texts that compile Ayurvedic knowledge, principles, and treatments. These texts serve as foundational references for Ayurvedic practitioners, guiding the understanding and management of conditions like diabetes and ensuring the integration of traditional wisdom into contemporary practice.
17) Activity:
Activity in the study context may relate to the therapeutic effects observed following the administration of various treatments. This includes both physiological responses and biochemical changes, highlighting how lifestyle modifications and herbal remedies can influence metabolic functions in patients with diabetes mellitus.
18) Nidana:
Nidana signifies the understanding of causative factors or diagnosis in Ayurveda. In studying diabetes, recognizing Nidana involves analyzing lifestyle choices, dietary habits, and physiological conditions contributing to the disease's onset, emphasizing the holistic approach to treatment and preventive strategies.
19) Kapha:
Kapha is one of the three doshas in Ayurveda, characterized by qualities such as heaviness and solidity. An imbalance in Kapha is implicated in the pathogenesis of diabetes and other metabolic disorders, providing a framework for understanding disease progression and developing appropriate treatment interventions.
20) Sutra:
Sutra translates to 'thread' or 'aphorism' in Sanskrit and is commonly used in Ayurvedic texts to convey condensed wisdom on health principles and practices. It serves as an essential guide for practitioners, aiding in the application of treatments for managing conditions like diabetes successfully.
21) Honey:
Honey is recognized for its potential health benefits in Ayurveda, particularly its sweetening properties and medicinal uses. Although often excluded from some diabetic diets due to high sugar content, its moderate use under controlled conditions might contribute positively to treatment regimens, promoting balance in metabolic processes.
22) Varanasi (Varanashi):
Varanasi is a city in India known for its historical significance in Ayurveda, being home to numerous Ayurvedic scholars and practitioners. The location symbolizes the rich cultural and educational heritage in the field, influencing the development of practices related to managing diseases such as diabetes.
23) Sharman (Sarma, Sharma, Sarman):
Sharma is a common surname in India, often associated with authors or researchers in Ayurvedic medicine. In the context of the study, it likely references an influential figure involved in Ayurvedic research, contributing knowledge and guidance for effective treatments in managing diabetes mellitus.
24) India:
India is the birthplace of Ayurveda, encompassing a vast array of healing practices and herbal medicines. The significance lies in integrating traditional wisdom with modern healthcare, particularly in managing chronic diseases like diabetes, reflecting India's rich heritage and contributions to global health.
25) Food:
Food relates directly to dietary practices and nutritional choices, which are critical in managing diabetes. The study underscores the importance of food as a determinant of health, emphasizing the role of proper nutrition in controlling blood sugar levels and overall well-being in patients with diabetes.
26) Line:
Line in the context of treatment implies the sequential approach to managing diabetes through different therapies, primarily in Ayurveda. It highlights the need for a structured treatment protocol to ensure comprehensive care, beginning with detoxification (Shodhana) followed by palliative treatments (Shamana).
27) Ghi (Ghee):
Ghee is clarified butter commonly used in Ayurveda for its digestive benefits and as part of detoxification processes. In the context of the study, ghee's role in the Vamana therapy underscores its significance in preparing the body for therapeutic interventions while promoting overall health and balance.
28) Sutrasthana (Sutra-sthana):
Sutra-sthana pertains to a specific section in Ayurvedic texts that addresses aphorisms related to health and treatments. It serves as an important reference point for practitioners, ensuring that traditional guidelines are followed accurately during treatment and contributing to effective management of diseases such as diabetes.
29) Diet:
Diet encompasses the nutritional framework individuals adhere to, which is crucial in the management of diabetes. It highlights the dietary restrictions and recommendations necessary for stabilizing blood sugar levels, emphasizing the importance of individualized dietary approaches rooted in Ayurvedic principles and contemporary nutritional science.
30) Post:
Post refers to the timeframe following the main treatment interventions, wherein monitoring for efficacy and safety occurs. In diabetes management, understanding post-treatment changes is vital for assessing the effectiveness of therapies and guiding subsequent adjustments to treatment plans for optimal patient care.
31) Agnivesha (Agnivesa, Agni-vesha):
Agnivesha is a revered figure in Ayurveda, credited with compiling significant Ayurvedic texts. His contributions laid the foundation for numerous treatment protocols, particularly concerning diseases like diabetes. Recognizing historical figures like Agnivesha emphasizes the importance of traditional wisdom in modern health practices and treatments.
32) Madhyama:
Madhyama translates to 'medium' in Sanskrit and is often used in Ayurveda to describe the degree of effectiveness or quality of treatment achieved. In the context of the study, it may relate to the classification of results observed from interventions in managing conditions like diabetes.
33) Water:
Water is essential for life and plays a crucial role in Ayurvedic practices as a medium for various therapies, including cleansing procedures. It underscores the importance of hydration in metabolic processes and may also be considered in dietary aspects for managing diabetes effectively.
34) Rules:
Rules in this context denotes the guidelines or protocols that govern the conduct of the study, ensuring adherence to ethical and scientific standards. Understanding established rules is fundamental to validating research outcomes and maintaining integrity in the exploration of treatments for diabetes mellitus.
35) Observation:
Observation signifies the careful monitoring of patient responses to various treatments throughout the study. It serves as a critical aspect of clinical research, allowing researchers to assess the effectiveness and potential adverse effects of the interventions employed in managing diabetes mellitus.
36) Dushya (Dusya):
Dushya refers to the components of the body or the substances affected by the doshas in Ayurveda. In dealing with conditions like diabetes, understanding the interaction of Dushya provides insights into disease pathways and informs treatment approaches focused on restoring balance and improving patient health.
37) Drug:
Drug refers to any substance used for medicinal purposes, including both traditional Ayurvedic remedies and conventional pharmaceuticals. In diabetes management, understanding the role of different drugs is crucial for developing effective treatment strategies that enhance patient outcomes under varying conditions of the disease.
38) Life:
Life signifies the holistic approach Ayurveda takes towards health and well-being, emphasizing the significance of balancing physical, mental, and emotional aspects. In dealing with chronic conditions like diabetes, this philosophy underscores the importance of treating the whole person rather than just the disease.
39) Composite:
Composite denotes the combination of different treatment approaches or modalities seen in the study, highlighting the integrative nature of managing diabetes. Utilizing both Ayurvedic methods and modern pharmacological interventions exemplifies a holistic strategy aimed at effectively addressing the complexities of the disease.
40) Triphala (Tri-phala):
Triphala is a traditional Ayurvedic formulation comprising three fruits known for their health benefits. In the context of diabetes management, Triphala is recognized for its potential to regulate blood sugar levels and support digestive health, thus serving an important role in the holistic treatment strategies employed.
41) Pravara:
Pravara translates to 'superior' or 'maximum' in Sanskrit, referencing the highest level of cleansing or purification achieved through therapies like Vamana. In this study, identifying treatment outcomes as Pravara underscores the effectiveness of the interventions in managing diabetes and restoring balance within the body.
42) Karma (Karman):
Karma refers to the actions or the therapeutic procedures carried out in Ayurveda. In this context, it speaks to the significance of various treatment modalities—like Vamana and Varadi Ghanavati—at their impacts on patient health, especially regarding the management of diabetes.
43) Delhi:
Delhi, the capital of India, is significant as a hub for Ayurvedic education and practice. The mention of Delhi highlights its central role in disseminating Ayurvedic knowledge and treatment options, influencing practices that address chronic ailments, including diabetes mellitus in diverse populations.
44) New Delhi:
New Delhi, specifically designated as the capital, suggests a location with deeper emphasis on governance and urban development. It stands out as a key site for healthcare advancements, including Ayurvedic methods, thereby impacting health policies and the integration of traditional practices into contemporary health systems.
45) Nidanasthana (Nidana-sthana):
Nidana-sthana refers to a segment of classical Ayurvedic texts outlining the causes and symptoms of various diseases including diabetes. This section serves as a fundamental resource for practitioners to understand the underlying factors behind Prameha, guiding targeted and effective treatment strategies to manage the condition.
46) Siddhisthana (Siddhi-sthana):
Siddhi-sthana represents the part of Ayurvedic texts dedicated to treatment outcomes and success stories related to various disorders. This section emphasizes the positive results achievable through proper Ayurvedic practice, reinforcing the value of traditional methods in effectively managing conditions like diabetes mellitus.
47) Abhyantara (Abhyamtara):
Abhyantara translates to 'internal' in Sanskrit, often used to refer to treatments targeting internal organs and systems in Ayurveda. In diabetes management, Abhyantara therapies might encompass dietary changes and herbal formulations aimed at restoring balance and improving overall metabolic functions for better health outcomes.
48) Daurbalya:
Daurbalya means weakness in Sanskrit, and it is one of the symptoms often associated with diabetes. Recognizing Daurbalya in patients provides a framework for understanding the overall impact of the disease on physical well-being, guiding interventions aimed at enhancing strength and energy levels.
49) Padatala (Pada-tala):
Pada-tala translates to 'the soles of the feet' and may refer to specific symptoms experienced by diabetic patients, such as numbness or burning sensations. In Ayurveda, understanding conditions that affect the extremities can inform treatment approaches aimed at alleviating discomfort and promoting sensory health through holistic practices.
50) Container:
Container refers to the packaging or storage used for medications and formulations in Ayurveda. The proper containment of herbal medicines ensures their stability and effectiveness, emphasizing the importance of quality control in the production and distribution of Ayurvedic treatments, particularly for managing complex conditions like diabetes.
51) Cleansing:
Cleansing refers to detoxification methods employed in Ayurveda, especially in the context of treatments like Vamana. It emphasizes the need to remove harmful toxins and metabolic waste from the body, underlining the foundational principle of restoring balance for effective management of conditions such as diabetes.
52) Pipilika:
Pipilika indicates the sensation of creeping or tingling often reported by diabetic patients, commonly known as neuropathy. Recognizing such symptoms allows practitioners to develop targeted therapeutic strategies aimed at mitigating discomfort and improving the quality of life for individuals living with diabetes.
53) Prabhuta:
Prabhuta means 'excessive' in Sanskrit, often describing symptoms like excessive urination in diabetic patients. Understanding excessive symptoms is crucial for developing comprehensive treatment protocols aimed at addressing and alleviating the burden of these manifestations in the management of diabetes.
54) Shleshma (Slesma):
Shleshma refers to the Kapha dosha in Ayurveda, associated with qualities of heaviness and moisture. It is regarded as a critical factor in conditions such as diabetes, making understanding its role essential for effective therapeutic interventions targeting the balance of doshas in the body.
55) Sweating (Sweat):
Sweating is a physiological response that can be related to various health conditions, including diabetes. In Ayurveda, excessive sweating is often associated with imbalances in doshas and may indicate the need for interventions aimed at restoring equilibrium and alleviating discomfort for affected individuals.
56) Kshudha (Ksudha):
Kshudha means 'hunger' in Sanskrit and can refer to the symptom of excessive appetite often seen in diabetes. Recognizing changes in appetite and satiation plays a crucial role in understanding the metabolic disturbances in diabetic patients, informing dietary modifications and therapeutic strategies to manage the condition effectively.
57) Burning (Burn, Burned, Burnt):
Burning refers to the sensation often experienced in the extremities or feet of diabetic patients, typically linked to nerve damage. Recognizing burning sensations allows for targeted therapies aimed at neural restoration and pain relief, which are critical for enhancing the quality of life in individuals living with diabetes.
58) Siddhi:
Siddhi translates to 'success' or 'achievement' in Sanskrit and highlights the positive outcomes derived from Ayurvedic treatments. In the context of Ayurveda, achieving Siddhi signifies effective management and resolution of disease symptoms, emphasizing the potential of integrated therapeutic approaches in enhancing patient health and wellness.
59) Pipasa:
Pipasa means 'thirst' in Sanskrit and can be a significant symptom in diabetes due to hyperglycemia. Managing excessive thirst through hydration strategies and dietary modifications is essential in diabetes care, ensuring that lifestyle factors are aligned with overall treatment goals for optimal patient outcomes.
60) Indian:
Indian refers to the cultural and geographical context from which Ayurveda originates. The teachings and practices in Ayurveda are deeply rooted in Indian tradition and philosophy, contributing to a rich heritage of knowledge aimed at promoting health and treating various diseases, including diabetes mellitus.
61) Drava:
In Ayurveda, Drava refers to 'liquids' or 'fluids' in the body, including various bodily humors. Understanding the role of Drava is critical, as imbalances in bodily fluids can lead to conditions like diabetes, necessitating interventions aimed at restoring proper fluid dynamics for better health outcomes.
62) Nakta:
Nakta means 'night' in Sanskrit, often highlighting symptoms or conditions that manifest during nighttime, such as nocturia in diabetes. Recognizing these manifestations allows practitioners to tailor therapies for better management, ensuring that treatment plans address the full spectrum of a patient's experience with their condition.
63) Avila:
Avila translates to 'turbid' or 'cloudy' and is frequently associated with urine quality in diabetes. This symptom serves as an important indicator for Ayurvedic practitioners in diagnosing diabetes, enabling targeted interventions aimed at improving metabolic health and restoring balance to bodily functions.
64) Dhatu:
Dhatu refers to the seven fundamental tissues in Ayurveda crucial for maintaining bodily health. Proper balance of Dhatus is essential as they contribute to overall metabolic functions. Imbalances in Dhatu can have implications for diabetes management, highlighting the need for integrated treatments to restore equilibrium.
65) Bahu:
Bahu translates to 'many' or 'excessive', often relating to the accumulation of dosha or other components in the body. In the context of managing diabetes, Bahu reflects the importance of addressing excess dosha through targeted interventions like Shodhana to restore healthy body functions and improve overall health.
66) Tala:
Tala means 'soles' or 'feet', which may signify the importance of foot care in diabetic patients. Understanding the implications of foot health in diabetes management is crucial to prevent complications, as peripheral neuropathy often leads to sensations of pain or numbness, necessitating effective treatment approaches.
67) Pada:
Pada means 'foot' in Sanskrit and can denote aspects of care in Ayurvedic practice relevant to the lower extremities, particularly in diabetic patients. The incorporation of holistic foot care strategies is essential in managing complications linked to diabetes, ensuring comprehensive treatment for overall well-being.
68) Daha:
Daha translates to 'burning' and is often referenced in Ayurveda to describe sensations or symptoms experienced by patients. It has clinical significance in the diagnosis of conditions like diabetes, as recognizing burning sensations in extremities can lead to targeted therapeutic interventions to enhance comfort and quality of life.
69) Cyperus rotundus:
Cyperus rotundus, known as Musta in Ayurveda, is a medicinal herb recognized for its antidiabetic properties. Its inclusion in formulations signifies the blending of traditional knowledge with pharmacological insights, facilitating effective treatment options for managing diabetes mellitus and balancing doshas within the body.
70) Purification:
Purification in Ayurveda pertains to cleansing rituals aimed at detoxifying the body from accumulated toxins or imbalances. Procedures like Vamana promote detoxification, illustrating the holistic approach to restoring health and balance in patients with chronic conditions, including diabetes mellitus, emphasizing overall well-being.
71) Daruharidra (Daru-haridra):
Daruharidra refers to Berberis aristata, an important Ayurvedic herb known for its therapeutic properties, including antidiabetic effects. Its role in the study underscores the importance of traditional herbal medicine in managing diabetes and highlights its efficacy in reducing blood sugar levels and restoring metabolic balance.
72) Yashtimadhu (Yastimadhu, Yashti-madhu):
Yashtimadhu, or Glycyrrhiza glabra, is a well-known Ayurvedic herb with anti-inflammatory and medicinal properties. Its inclusion in treatment protocols for diabetes highlights the significance of herbal remedies in enhancing metabolic processes and alleviating symptoms, demonstrating the synergistic approach of Ayurveda in chronic disease management.
73) Samshodhana (Samsodhana):
Samshodhana indicates the process of detoxification or purification in Ayurveda, essential in initiating treatment for conditions like Prameha (diabetes). This term emphasizes the foundational step of cleansing before proceeding with palliative treatments, showcasing the structured approach to managing metabolic imbalances and improving health outcomes.
74) Shaithilya (Saithilya):
Shaithilya translates to 'flaccidity' concerning the weakening of body components. Recognizing this condition in Ayurveda can lead to timely interventions aimed at strengthening the body's systems, particularly when addressing chronic diseases like diabetes mellitus, underscoring the holistic perspective of Ayurvedic medicine.
75) Avaraniya:
Avaraniya refers to the blocking or obstructive nature of certain doshas, which can lead to diseases like diabetes. Understanding this concept helps practitioners identify and treat the root causes of health issues in Ayurveda, promoting effective management strategies aimed at restoring balance and health.
[Note: The above list is limited to 75. Total glossary definitions available: 175]
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