Effect of Vajigandhadi Gana and Kolakulathadi in Knee Osteoarthritis
Journal name: Ayushdhara
Original article title: Combined Effect of Vajigandhadi Gana Kashaya and Kolakulathadi Churnam in the Management of Janu Sandhigata Vata w.s.r. to Osteoarthritis of Knee Joint
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Rameshwari
PG Scholar, PG Department of Kayachikitsa, Sri Jayendra Saraswathi Ayurveda College and Hospital, Tamil Nadu, India
Suvendu Rout
Professor and HOD, PG Department of Kayachikitsa, Sri Jayendra Saraswathi Ayurveda College and Hospital, Tamil Nadu, India
Soumya E A
Assistant Professor, PG Department of Kayachikitsa, Sri Jayendra Saraswathi Ayurveda College and Hospital, Tamil Nadu, India
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: Combined Effect of Vajigandhadi Gana Kashaya and Kolakulathadi Churnam in the Management of Janu Sandhigata Vata w.s.r. to Osteoarthritis of Knee Joint
Year: 2022 | Doi: 10.47070/ayushdhara.v9i5.1074
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Introduction
Janu Sandhigata Vata, commonly referred to as osteoarthritis in modern medical terminology, is a prevalent disorder impacting many individuals, especially in midlife and beyond. It is characterized by the aggravation of Vata dosha, which can lead to joint pain, inflammation, and impaired movement. This study investigates the efficacy of two Ayurvedic formulations, Vajigandhadi Gana Kashaya and Kolakulathadi Churna, used in combination for the management of Janu Sandhigata Vata. The study aims to evaluate their effectiveness in alleviating the symptoms associated with knee osteoarthritis among aged individuals.
Efficacy of Vajigandhadi Gana Kashaya
The formulation of Vajigandhadi Gana Kashaya consists of various herbal ingredients known for their properties that are beneficial in managing Vata and Kapha imbalances. It has been designed to possess qualities such as Ushna virya (heating), Vatahara (subduing Vata), and Shula hara (pain-relieving). This formulation serves as an internal remedy that aims to alleviate pain, inflammation, and swelling in the affected joints. The results of the study indicated a marked improvement in subjective symptoms such as Sandhi Shula (joint pain) and Sandhi Shotha (joint swelling) after treatment, aligning with statistical analyses that demonstrated significant relief from discomfort.
Effectiveness of Kolakulathadi Churna as Local Application
Kolakulathadi Churna, administered as a topical lepa (externally applied remedy), complements the internal treatment with its own potent effects. This formulation is rich in compounds known for their ability to harbor Ushna virya, Vatahara, and Shotha hara properties. The study underlines how its application can enhance local circulation and reduce inflammation in the joint area where applied. The results showed that subjects experienced considerable relief in symptoms such as stiffness and crepitus (cracking sounds in joints) after the use of this topical application, corroborated by significant improvements in objective parameters such as the range of movements and associated WOMAC scores.
Conclusion
The combination of Vajigandhadi Gana Kashaya and Kolakulathadi Churna has been proven effective in managing Janu Sandhigata Vata (osteoarthritis of the knee joint), demonstrating significant symptomatic relief and improvement in joint mobility. This study highlights the potential of Ayurvedic formulations in providing therapeutic benefits for chronic conditions commonly affecting the elderly population. With marked efficacy and no reported complications, the findings suggest a promising avenue for treating osteoarthritis while also pointing to the need for further research employing advanced diagnostic tools in future studies to enhance the understanding of these therapies.
FAQ section (important questions/answers):
What is Janu sandhigata vata in Ayurveda?
Janu sandhigata vata is a disorder affecting the knee joint, often compared to osteoarthritis. It involves vitiation of Vata dosha, leading to symptoms like pain, swelling, and stiffness, particularly prevalent in individuals after midlife.
What treatments were analyzed in the study?
The study evaluated the combined effect of Vajigandhadi gana Kashaya and Kolakulathadi Churna as Lepam in managing Janu sandhigata vata. They possess properties that help alleviate symptoms like pain, swelling, and stiffness around the knee.
What were the significant findings of the study?
The study demonstrated that the treatments significantly improved symptoms of Janu sandhigata vata, including pain reduction and increased range of motion. Statistical analysis showed highly significant results indicating the effectiveness of the interventions.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Effect of Vajigandhadi Gana and Kolakulathadi in Knee Osteoarthritis�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Vata:
Vata is one of the three doshas in Ayurveda, responsible for movement and various bodily functions. It gets vitiated in conditions like Sandhigata Vata, leading to symptoms such as pain and inflammation in joints.
2) Sandhi (Shandhi, Samdhi):
Sandhi refers to joints in the body. In the context of Sandhigata Vata, Vata dosha influences the Sandhi, leading to various issues such as pain, stiffness, and swelling associated with osteoarthritis.
3) Sandhigata Vata (Sandhigata-vata):
[see source text or glossary: Sandhigata-vata]
4) Hara:
Hara means 'to remove' or 'to alleviate.' In Ayurvedic formulations, it is used to denote the properties that alleviate symptoms like Shula (pain) or Shotha (inflammation).
5) Janu:
Janu refers to the knee in Ayurveda. In cases like Janu Sandhigata Vata, the knee joint is specifically affected by Vata dosha, leading to osteoarthritis-like symptoms.
6) Kashaya (Kasaya):
Kashaya is a type of Ayurvedic decoction or herbal preparation. Vajigandhadi Gana Kashaya is used internally in the management of Janu Sandhigata Vata.
7) Drug:
Drugs in Ayurveda like Vajigandhadi Gana Kashaya and Kolakulathadi Churna are formulated to manage conditions such as Janu Sandhigata Vata by providing properties like Shula hara (pain relief) and Shotha hara (anti-inflammatory).
8) Gana:
Gana refers to a group of herbs that are used collectively in Ayurvedic medicine. The Vajigandhadi Gana is a specific herbal formulation used for its therapeutic properties.
9) Shula (Sula):
Shula refers to pain. In the context of Sandhigata Vata, Shula manifests as joint pain, especially in the knees, which the Ayurvedic treatments aim to alleviate.
10) Shotha (Sotha):
[see source text or glossary: Sotha]
11) Dosha (Dosa):
Dosha are biological energies in Ayurveda comprising Vata, Pitta, and Kapha. Imbalance in these doshas, especially Vata dosha, leads to conditions like Sandhigata Vata (osteoarthritis).
12) Kapha:
Kapha is one of the three doshas in Ayurveda, associated with structure and lubrication. An imbalance in Kapha along with Vata can exacerbate conditions like Sandhigata Vata.
13) Pain:
Pain, or Shula in Ayurveda, is a primary symptom of Sandhigata Vata. It significantly impacts quality of life and is addressed through Ayurvedic treatments that possess Shula hara properties.
14) Disease:
Disease in Ayurveda like Sandhigata Vata involves Vata dosha affecting joints, leading to symptoms such as pain, stiffness, and inflammation. Ayurvedic therapies aim to balance the doshas to treat the disease.
15) Lepa:
Lepa refers to a type of external application or paste used in Ayurvedic treatments. Kolakulathadi Churna used as Lepam is applied to alleviate symptoms like pain and swelling in Janu Sandhigata Vata.
16) Shothahara (Sothahara, Shotha-hara):
[see source text or glossary: Sothahara]
17) Vatadosha (Vatadosa, Vata-dosha):
Vata-dosha is one of the primary doshas in Ayurveda, governing movement and bodily functions. Its vitiation leads to conditions like Sandhigata Vata, which causes joint issues such as osteoarthritis.
18) Vyadhin (Vyadhi):
Vyadhi means disease in Ayurveda. Conditions like Janu Sandhigata Vata are categorized under Vyadhi, which involves the imbalance of Doshas leading to various symptoms in the body.
19) Atopa:
Atopa refers to crepitus or the crackling sound heard in joints. In Sandhigata Vata, it is a common symptom indicating joint degeneration and is assessed in Ayurvedic treatments.
20) Vedanasthapana (Vedana-sthapana):
Vedana-sthapana means pain-relieving. It's a property of many Ayurvedic drugs used in the treatment of Janu Sandhigata Vata to alleviate pain (Vedana).
21) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine focusing on balancing the body's doshas (Vata, Pitta, Kapha) to treat diseases. Treatments for Janu Sandhigata Vata include various herbal formulations.
22) Rasayana (Rasa-ayana):
Rasayana refers to rejuvenative therapies in Ayurveda. Drugs like Vajigandhadi Gana Kashaya used for Janu Sandhigata Vata may have Rasayana properties to strengthen and rejuvenate tissues.
23) Sthapana:
[see source text or glossary: Sthapana]
24) Vedana:
Vedana means pain in Ayurveda. The term is crucial in diagnosing conditions like Janu Sandhigata Vata, where pain management is a primary treatment objective.
25) Patra:
Patra means leaf. In formulations like Kolakulathadi Lepam, various plant parts, including leaves or Patra, are used for their medicinal properties.
26) Ushna (Usna):
Ushna means hot or heating in Ayurveda. Many drugs with Ushna Virya (hot potency) are used to treat Vata disorders like Janu Sandhigata Vata because they counteract Vata's cold qualities.
27) Virya:
Virya refers to the potency or energetic effect of a substance. In the context of treating Janu Sandhigata Vata, drugs with Ushna Virya counteract the cold nature of Vata dosha.
28) Rasa (Rasha):
Rasa means taste, which plays a role in the therapeutic properties in Ayurveda. For instance, Tikta Rasa (bitter taste) has properties like Deepana and Pachana, which are useful in treating Sandhigata Vata.
29) Prakopa:
[see source text or glossary: Prakopa]
30) Nidana:
Nidana refers to the causative factors of a disease. In Janu Sandhigata Vata, Nidanas include factors like Vata Prakopa Ahara (diet) and Vihara (activities) that aggravate Vata dosha.
31) Tikta:
Tikta means bitter taste in Ayurveda. Many herbs used to treat Sandhigata Vata have Tikta Rasa, which has Deepana (appetizing) and Pachana (digestive) properties.
32) Dhatu:
Dhatu refers to the tissues of the body in Ayurveda. In conditions like Sandhigata Vata, the Dhatus, particularly Asthi (bone) and Majja (marrow), are affected by Vata dosha.
33) Balya:
Balya refers to a strengthening property in Ayurveda. Herbs like Bala and Atibala used in Sandhigata Vata treatment possess Balya properties to strengthen the body tissues.
34) Shalaparni (Salaparni):
[see source text or glossary: Shala-parni]
35) Discussion:
[see source text or glossary: Discussion]
36) Samprapti:
Samprapti refers to the pathogenesis or process of disease formation in Ayurveda. Understanding the Samprapti of Janu Sandhigata Vata helps in selecting the appropriate Ayurvedic treatments to alleviate symptoms.
37) Abhighata:
Abhighata means trauma or injury. In the context of Sandhigata Vata, trauma to the joints (Abhighata) is one of the factors that can aggravate Vata dosha, leading to joint issues.
38) Vatahara (Vata-ahara):
Vatahara means to alleviate or pacify Vata dosha. Ayurvedic treatments for Sandhigata Vata use Vatahara herbs to balance the aggravated Vata and relieve symptoms like pain and stiffness.
39) Stiffness:
Stiffness, or Sandhi Stabdata, is one of the primary symptoms of Sandhigata Vata. It indicates restricted mobility in the joints, which Ayurvedic treatments aim to alleviate.
40) Nagabala (Naga-bala):
Nagabala is a herb used in Ayurveda with properties like Balya (strengthening) and Rasayana (rejuvenative). It is part of the formulation Vajigandhadi Gana Kashaya used in treating Sandhigata Vata.
41) Gambhari:
Gambhari is an herb used in Ayurveda, possessing properties like Balya and Rasayana. It is part of the Vajigandhadi Gana, which is used to manage Sandhigata Vata.
42) Gokshura (Goksura, Go-kshura):
Gokshura is a medicinal herb used in Ayurveda known for its Balya and Rasayana properties. It is an ingredient in Vajigandhadi Gana Kashaya, used to treat Sandhigata Vata.
43) Atibala:
Atibala is a strengthening (Balya) herb used in Ayurveda. It is included in the formulation Vajigandhadi Gana Kashaya, which is effective in treating joint disorders like Sandhigata Vata.
44) Avastha:
[see source text or glossary: Avastha]
45) Shyonaka (Syonaka):
[see source text or glossary: Syonaka]
46) Sthana:
[see source text or glossary: Sthana]
47) Kshaya (Ksaya):
[see source text or glossary: Kshaya]
48) Rasna (Rashna, Rasona, Rasa-una):
Rasna is an herb used in Ayurveda for its Shula hara (pain-relieving) properties, making it effective in formulations aimed at treating Sandhigata Vata.
49) Ahara:
Ahara means diet. In Ayurveda, the type of Ahara can influence dosha balance, and a Vata-aggravating diet can worsen conditions like Sandhigata Vata.
50) Shala (Sala):
[see source text or glossary: Shala]
51) Sida (Shida):
[see source text or glossary: Sida]
52) Bala:
Bala is an herb known for its strengthening (Balya) properties. It is part of the Vajigandhadi Gana Kashaya, which is used in treating conditions like Sandhigata Vata.
53) Food:
[see source text or glossary: Food]
54) Solanum xanthocarpum:
Solanum xanthocarpum, known as Kanthakari in Ayurveda, is used in formulations like Vajigandhadi Gana for its therapeutic properties, including treating Sandhigata Vata.
55) Rheumatoid arthritis:
Rheumatoid arthritis is an autoimmune disease that affects joints. It is excluded from studies like the one on Janu Sandhigata Vata (osteoarthritis) due to different etiopathogenesis.
56) Zingiber officinale:
Zingiber officinale, known as Shunthi or ginger, is used in Ayurvedic formulations for its Deepana and Pachana properties, making it effective in treating disorders like Sandhigata Vata.
57) Premna integrifolia:
[see source text or glossary: Premna integrifolia]
58) Withania somnifera:
Withania somnifera, known as Ashwagandha, is used in Ayurveda for its adaptogenic and Balya properties, making it useful in treating conditions like Sandhigata Vata.
59) Dolichos biflorus:
[see source text or glossary: Dolichos biflorus]
60) Saussurea lappa:
[see source text or glossary: Saussurea lappa]
61) Solanum indicum:
[see source text or glossary: Solanum indicum]
62) Stereospermum suaveolens:
[see source text or glossary: Stereospermum suaveolens]
63) Desmodium gangeticum:
Desmodium gangeticum, known as Shala parni, is used in Ayurveda for its Deepana and Pachana properties. It is part of preparations like Vajigandhadi Gana Kashaya for treating Sandhigata Vata.
64) Tribulus terrestris:
Tribulus terrestris, also known as Gokshura, is used in Ayurveda for its Balya and Rasayana properties, making it effective in treating joint disorders like Sandhigata Vata.
65) Oroxylum indicum:
[see source text or glossary: Oroxylum indicum]
66) Ricinus communis:
[see source text or glossary: Ricinus communis]
67) Gmelina arborea:
Gmelina arborea, known as Gambhari, is part of the Vajigandhadi Gana Kashaya used in Ayurveda. It has Rasayana and Balya properties, beneficial for treating Sandhigata Vata.
68) Hordeum vulgare:
[see source text or glossary: Hordeum vulgare]
69) Pharmacological:
[see source text or glossary: Pharmacological]
70) Bhrajakapitta (Bhrajaka-pitta):
[see source text or glossary: Bhrajaka-pitta]
71) Acorus calamus:
[see source text or glossary: Acorus calamus]
72) Transformation (Transform, Transforming):
[see source text or glossary: Transformation]
73) Prishniparni (Prsniparni, Prishni-parni):
Prishni-parni, also known as Uraria picta, is used in Ayurveda for its Balya properties. It is an ingredient in Vajigandhadi Gana Kashaya, effective against Sandhigata Vata.
74) Tridoshahara (Tridosahara, Tridosha-hara):
Tridosha-hara means a substance that balances all three doshas (Vata, Pitta, Kapha). Formulations like Dashamoola used in treating Sandhigata Vata possess Tridosha-hara properties.
75) Dhatukshaya (Dhatuksaya, Dhatu-kshaya):
Dhatu-kshaya refers to the depletion of bodily tissues. In Sandhigata Vata, Dhatu-kshaya primarily affects Asthi (bones) and Majja (marrow), leading to the joint degeneration seen in osteoarthritis.
[Note: The above list is limited to 75. Total glossary definitions available: 150]
Other Science Concepts:
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