In vitro antioxidant activities of Asteraceae Plants
Journal name: Ancient Science of Life
Original article title: In vitro antioxidant activities of Asteraceae Plants
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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S. Vijaylakshmi, M. J. Nanjan, B. Suresh
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: In vitro antioxidant activities of Asteraceae Plants
Year: 2009
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
Anaphalis neelgerriana DC and Cnicus wallichi DC, both members of the Asteraceae (Compositae) family, are notable medicinal plants indigenous to the Nilgiris region of South India. These species are recognized for their therapeutic applications, including wound treatment and antiseptic properties. The aerial parts of these plants exhibit significant antioxidant activity, attributed to the presence of chemical compounds such as sesquiterpenes, flavonoids, and steroids. Studies have demonstrated their potential for cancer treatment, highlighting a need for further investigation of their medicinal properties through in vitro antioxidant activity assessments.
Significance of Antioxidant Activity
The antioxidant activity of Anaphalis neelgerriana DC and Cnicus wallichi DC was evaluated using various in vitro methods, including DPPH, nitric oxide, and hydrogen peroxide scavenging assays. The results indicated that the ethyl acetate extracts from both plants exhibited significant antioxidant effects, with the ethyl acetate extract of Anaphalis neelgerriana DC showing the most pronounced activity across all evaluation methods. The preliminary phytochemical screening confirmed the presence of antioxidants like flavonoids, which can inhibit free radicals and lipid peroxidation. These findings support the plants' therapeutic potential and suggest that their extracts may act as effective natural antioxidants.
Conclusion
In conclusion, the ethyl acetate extracts of Anaphalis neelgerriana DC and Cnicus wallichi DC demonstrate substantial in vitro antioxidant activity, providing a scientific basis for their traditional use in herbal medicine. The presence of flavonoids within these extracts underscores their importance in preventing oxidative stress and related diseases, including cancer. Further studies, particularly involving in vivo models, are warranted to explore the full potential of these plants as natural antioxidants and their implications in the treatment of oxidative stress-related conditions.
FAQ section (important questions/answers):
What are the medicinal properties of Anaphalis neelgerriana and Cnicus wallichi?
Anaphalis neelgerriana and Cnicus wallichi are recognized for their antioxidant properties and traditional uses in treating wounds, ulcers, and inflammation. They contain active compounds such as flavonoids and steroids, which contribute to their medicinal value.
How were the antioxidant activities of the plants tested?
The antioxidant activities were evaluated using DPPH, Nitric oxide, and Hydrogen peroxide scavenging activity assays. A series of extracts from the plants were prepared and their effects on free radicals were measured to determine their potency.
What extracts showed significant antioxidant activity?
The ethyl acetate extracts of both Anaphalis neelgerriana and Cnicus wallichi demonstrated significant antioxidant activity across all tested methods, indicating their potential health benefits and effectiveness as natural antioxidants.
What compounds were found in the plants' extracts?
Preliminary phytochemical analysis revealed the presence of flavonoids, steroids, triterpenoids, phenolics, and carbohydrates in the aerial parts of both plants, contributing to their antioxidant properties.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “In vitro antioxidant activities of Asteraceae Plants�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Activity:
Activity refers to the capacity of certain substances, in this case, plant extracts, to produce a biological effect. In the context of this study, antioxidant activity is crucial as it demonstrates the ability of extracts from Anaphalis neelgerriana DC and Cnicus wallichi DC to neutralize free radicals, which can damage cells and contribute to various diseases, including cancer.
2) Phytochemical:
Phytochemicals are naturally occurring compounds found in plants that can have beneficial effects on health. This study identifies various phytochemicals in Anaphalis neelgerriana DC and Cnicus wallichi DC, such as flavonoids and steroids, which are studied for their medicinal properties, including antioxidant and anti-inflammatory effects.
3) Cancer:
Cancer is a disease characterized by uncontrolled cell growth and division. The relevance of cancer in this study is significant as it investigates the antioxidant properties of the tested plant extracts, which may help in preventing or treating cancer by neutralizing free radicals that can cause cellular damage and mutations.
4) Flavonoid:
Flavonoids are a type of phytochemical known for their antioxidant properties and potential health benefits. This study emphasizes the presence and activity of flavonoids in Anaphalis neelgerriana DC and Cnicus wallichi DC, supporting their potential use in reducing oxidative stress, which is linked to various diseases, including cancer.
5) Science (Scientific):
Scientific pertains to methods and principles that are based on empirical evidence, systematic observation, and experimentation. This study employs scientific techniques to measure and analyze the antioxidant activity of plant extracts, reinforcing the importance of evidence-based research in validating traditional medicinal practices.
6) Himalaya (Hima-alaya):
The Himalaya refers to a major mountain range in Asia, home to many indigenous plants with medicinal properties. The significance of the Himalaya in this study lies in the origin of Anaphalis neelgerriana DC, highlighting the region's rich biodiversity and the potential for discovering new medicinal plants utilized in traditional medicine.
7) Palani (Pazhani):
Palani is a hill region in South India recognized for its unique flora and fauna. The importance of Palani in this study relates to its geographical significance as a habitat for Cnicus wallichi DC, which forms part of the explored medicinal plants, thereby showcasing the area's ecological contributions to herbal medicine.
8) Inflammation:
Inflammation is a biological response to harmful stimuli, often leading to tissue damage and disease. This study highlights the traditional use of Anaphalis neelgerriana DC and Cnicus wallichi DC for treating inflammation-related issues, showcasing the potential therapeutic effect of plant extracts against inflammatory processes.
9) Accumulation (Accumulating, Accumulate):
Accumulated refers to the gradual gathering or collection of something over time. In this context, it pertains to the increasing evidence and knowledge base regarding the antioxidant properties and activities of plant extracts, emphasizing the ongoing research in the field of medicinal plants and their health benefits.
10) Discussion:
Discussion in scientific research refers to the section where the authors interpret their findings in the context of existing knowledge. In this study, the discussion elaborates on the implications of the antioxidant activities observed, linking them to the potential therapeutic roles of the studied plants in managing oxidative stress and related diseases.
11) Mutation:
Mutation is a change in the DNA sequence that can lead to various consequences, including cancer. The relevance of mutation in this study relates to the understanding of how oxidative stress from free radicals can induce genetic changes, thereby underlining the importance of antioxidant activities in preventing cellular mutations that can lead to diseases.
12) Ulcer:
Ulcer refers to a sore on the skin or a mucous membrane resulting from cell loss. This study explores the traditional uses of Anaphalis neelgerriana DC in treating ulcers, supporting the notion that plant extracts may possess healing properties and providing a basis for scientific exploration of their efficacy as wound treatments.
13) Drug:
A drug is a substance used for medical treatment to diagnose, cure, mitigate, or prevent disease. The relevance of drug in this study relates to the potential of compounds found in Anaphalis neelgerriana DC and Cnicus wallichi DC as sources for developing new herbal medicines or supplements with antioxidant properties.
14) Inci (Imci):
Inch is a unit of measurement equivalent to 2.54 centimeters. While its significance in this study is minimal, it may refer to measurements in experimental setups or laboratory work; precision in measurements is crucial for reproducibility and validity in scientific experiments, including those evaluating antioxidant activities.
Other Science Concepts:
Discover the significance of concepts within the article: �In vitro antioxidant activities of Asteraceae Plants�. Further sources in the context of Science might help you critically compare this page with similair documents:
Flavonoid, Cooling effect, Antioxidant activity, Preliminary phytochemical screening, Galactogogue, Hydrogen peroxide, In vitro antioxidant activity, Antiseptic, Free Radical, Nitric Oxide Radical Scavenging Activity, Aerial part, Ethanol acetate extract, DPPH radical scavenging activity assay.