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A case study on virechana in sthul madhumeha and its impact on homa ir

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Journal name: World Journal of Pharmaceutical Research
Original article title: A case study on virechana in sthul madhumeha and its impact on homa ir
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Author:

Dr. Thatere A. A., More S. S. and Kabra P. R.


World Journal of Pharmaceutical Research:

(An ISO 9001:2015 Certified International Journal)

Full text available for: A case study on virechana in sthul madhumeha and its impact on homa ir

Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research

Doi: 10.20959/wjpr202014-18123

Copyright (license): WJPR: All rights reserved


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Summary of article contents:

Introduction

Diabetes Mellitus (DM) is a complex metabolic disorder characterized by hyperglycemia due to defects in insulin secretion and action. The condition can be understood through both modern medical perspectives and traditional Ayurvedic concepts. In Ayurveda, DM is referred to as Madhumeha and is classified into two types based on body constitution: Sthula (obese) and Krish (lean). Treatment strategies aim to balance the underlying doshas, emphasizing the importance of therapeutic procedures like Virechana (purification therapy) for managing symptoms and improving insulin resistance, particularly in cases of Sthula Madhumeha.

Virechana: A Key Ayurvedic Intervention

Virechana is an Ayurvedic therapeutic procedure classified as Shodhana, which is aimed at detoxifying and purifying the body. It is particularly indicated for managing Sthula Madhumeha. The process involves the use of specific herbal formulations, such as Panchatikta Ghrita, which possess properties that help normalize Kapha and Pitta doshas. This intervention not only facilitates the removal of accumulated doshas from the body but also stabilizes metabolic functions, thus potentially reducing obesity and improving insulin sensitivity. By administering Virechana, the study suggests that a significant reduction in insulin resistance, as measured by HOMA-IR, can be achieved.

Impacts on Blood Sugar and Insulin Levels

The study documented the therapeutic effects of Virechana on blood glucose levels in a 57-year-old female patient suffering from Type 2 diabetes. Initial assessments indicated elevated fasting and post-prandial blood sugar levels. Following the Virechana treatment, the patient's fasting blood sugar levels dropped from 141 mg/dl to 113 mg/dl, while post-prandial levels decreased from 242 mg/dl to 170 mg/dl. Additionally, serum insulin levels showed a significant decrease, indicating improved metabolic control and reduced insulin resistance post-treatment. This highlights the efficacy of Ayurvedic interventions in managing diabetes by targeting underlying metabolic imbalances.

Regulating Body Composition

The effects of the Ayurvedic treatment were also observed in the patient's body composition, particularly in her Body Mass Index (BMI) and waist-to-hip ratio (W:H ratio). Throughout the treatment, the patient's weight decreased from 73 kg to 68 kg, resulting in an improved BMI from 30 to 27.3. This reduction in body weight and modifications in waist circumference suggest not only a direct impact on obesity but also a correlation with enhancements in metabolic health, demonstrating the holistic approach of Ayurveda in managing lifestyle-related disorders like diabetes.

Conclusion

This case study illuminates the potential of Ayurvedic therapeutic interventions, particularly Virechana, in managing Sthula Madhumeha. The observed improvements in blood sugar levels, insulin resistance, and body composition underscore the effectiveness of traditional practices in contemporary health care. However, since this study was conducted on a single patient, further research on a larger sample size is necessary to substantiate these findings and develop conclusive treatment recommendations. The integration of Ayurveda into modern diabetes management might offer new avenues for comprehensive care and prevention strategies.

FAQ section (important questions/answers):

What is the relationship between Diabetes Mellitus and Madhumeha?

Diabetes Mellitus is similar to Madhumeha in Ayurvedic terms, characterized by hyperglycemia. Charak classified Madhumeha into Sthula and Krisha types based on their management, indicating that Shodhana (purification) treatment is appropriate for Sthula Madhumeha.

What is Virechana in Ayurvedic treatment?

Virechana is a detoxification process aimed at cleansing the body of excess Kapha and Kleda. It helps in stabilizing metabolic functions and reducing symptoms associated with Sthula Madhumeha by facilitating the expulsion of morbid doshas.

How does obesity affect insulin resistance in diabetes?

Obesity, particularly intra-abdominal fat, releases free fatty acids that compete with glucose for oxidation. This competition leads to impaired insulin signaling, causing reduced glucose utilization and increased glucose production, contributing to hyperglycemia and insulin resistance.

What were the results of the case study on Virechana?

Results indicated significant reductions in blood sugar levels, serum insulin, and HOMA-IR values. The patient also showed decreased body mass index (BMI) and improvement in various symptoms of Sthula Madhumeha after Virechana treatment.

What are some key symptoms of Sthula Madhumeha addressed in the treatment?

Key symptoms include weight gain, fatigue, increased hunger, and excessive sweating. The treatment aimed to alleviate these symptoms through dietary management, herbal medications, and detoxification procedures like Virechana.

What further research is suggested based on the study findings?

The study suggests conducting larger sample size investigations to establish the effectiveness of Ayurvedic treatments like Virechana for managing Sthula Madhumeha, as results from this case study were promising but not definitive.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “A case study on virechana in sthul madhumeha and its impact on homa ir�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Table:
In a clinical study, tables are crucial for presenting data in an organized manner. They allow for easy comparison of results such as blood sugar levels over time, making it easier to visualize the impact of treatment interventions. This facilitates better understanding and interpretation of research findings.

2) Kapha:
Kapha is one of the three doshas in Ayurveda, representing the elements of water and earth. It governs stability, structure, and lubrication in the body. Disorders related to Kapha, such as obesity and diabetes (Madhumeha), are treated through specific therapeutic interventions aimed at reducing its excess.

3) Study (Studying):
The term 'study' refers to an investigation or research project designed to understand a particular phenomenon or condition. In this context, it pertains to the examination of the effects of Virechana, an Ayurvedic detoxification method, on the management of Sthula Madhumeha and its underlying parameters.

4) Prameha:
Prameha is a term in Ayurveda corresponding to abnormal urination and metabolic disorders, notably diabetes mellitus. It highlights the importance of diagnosing an individual based on symptoms and underlying dosha imbalances, indicating a progression from simple metabolic disturbances to more complex conditions like Madhumeha.

5) Nagapura (Naga-pura):
Nagpur is the location of the Government Ayurved College and Hospital where the case study was conducted. The setting is significant as it represents a hub for Ayurvedic education and practice, contributing to the understanding and treatment of conditions like diabetes through traditional methods.

6) Homa:
HOMA (Homeostasis Model Assessment) refers to a method used to estimate insulin resistance and beta-cell function. In the context of the study, measuring HOMA-IR levels provides insight into the effectiveness of the treatment by evaluating changes in insulin sensitivity over different time points.

7) Medas (Meda, Medash):
Meda, or 'fat tissue', is an Ayurvedic term that highlights the role of excess fat accumulation in conditions like Madhumeha. Treatments aim to regulate Meda imbalances, restoring metabolic control and reducing obesity-related complications, ultimately improving the patient’s health outcomes.

8) Ghrita (Ghrta):
Ghrita refers to ghee, a clarified butter used in Ayurvedic treatments. It is characterized by its yogavahi properties, meaning it enhances the effect of other herbs and medicines. Panchatikta Ghrita, specifically, is employed to balance Kapha and support digestive health in diabetic patients.

9) Sthula:
Sthula translates to 'obese' or 'heavy', referring to individuals with excess body mass. In the context of Madhumeha, Sthula patients exhibit insulin resistance, necessitating targeted Ayurvedic interventions like Shodhana therapies to restore balance and promote overall health.

10) Vyadhin (Vyadhi):
Vyadhi is a Sanskrit term that denotes disease or disorder in Ayurveda. Understanding the specific Vyadhi changes the approach to treatment, indicating the need for individualized therapies based on the dosha imbalance and the patient's unique constitution.

11) Blood:
Blood is critical in the context of diabetes as it carries glucose and various metabolic byproducts throughout the body. Monitoring blood sugar levels is paramount during treatment to assess the effectiveness of dietary and therapeutic interventions in managing diabetes.

12) Rasa (Rasha):
Rasa represents the essence or taste of a substance in Ayurveda and implies its physiological effects on the body. The properties of Rasa are crucial in determining how medicines interact with doshas, especially when addressing conditions like diabetes through dietary choices and herbal remedies.

13) Observation:
The term 'observation' focuses on the act of closely monitoring a specific patient or group during a treatment. This is essential in clinical studies to evaluate individualized responses to therapies, leading to adjustments in treatment plans based on real-time data.

14) Samprapti:
Samprapti refers to the process of disease development in Ayurveda, outlining the stages from the initial dosha imbalance to clinical presentation. Understanding Samprapti is crucial for devising effective treatments, as it informs appropriate therapeutic interventions to reverse disease progression.

15) Daurbalya:
Daurbalya denotes weakness or debility in the body, often observed in individuals suffering from chronic conditions like diabetes. In this study, addressing Daurbalya is critical for holistic management, restoring the patient’s vitality and promoting overall health improvements during treatment.

16) Muhurmuhuh (Muhurmuhur, Muhur-muhu, Muhur-muhur, Muhurmuhu):
Muhurmuhu describes the notion of repeated successive actions or applications in Ayurveda. In the context of this case study, it illustrates the protocol of administering certain herbal drinks or treatments periodically to maximize therapeutic efficacy.

17) Lakshana (Laksana):
Lakshana refers to clinical signs or symptoms of a disease. In diagnosing and treating conditions like Sthula Madhumeha, accurate identification of Lakshana helps tailor interventions, improving individualized care and facilitating better health outcomes for patients.

18) Pradhan:
Pradhan meaning 'chief' or 'primary' in Ayurveda is often used to identify dominant doshas contributing to a disease. In managing diabetes, recognizing which dosha predominates allows practitioners to adopt targeted strategies to rebalance the body’s constitution and alleviate symptoms.

19) Dosha (Dosa):
Doshas are bioenergetic principles in Ayurveda that govern physical and mental processes. An imbalance in these doshas often leads to disease, and understanding their role is integral to developing personalized treatment plans, particularly in managing metabolic disorders like diabetes.

20) Kleda:
Kleda translates to moisture or fluid, which can represent an imbalance in metabolic functions within the body. In the context of Ayurveda, addressing excess Kleda is essential in treating Sthula Madhumeha due to its implications in weight gain and metabolic issues.

21) Tikta:
Tikta refers to the bitter taste in Ayurveda, considered cooling and detoxifying. It is significant in the treatment of obesity and diabetes as it helps purge excess Kapha and promotes digestive fire (Agni), essential for managing blood sugar levels.

22) Sveda:
Sveda denotes sweating in Ayurveda, which serves as a detoxifying mechanism. It plays a role both in treatment (like Svedana therapy) and as a symptom in disorders, highlighting the need to manage excessive sweating often seen in metabolic disorders.

23) Sugar:
Sugar, specifically glucose, is a vital energy source, but its dysregulation leads to diabetes mellitus. Understanding the impact of dietary sugar intake is fundamental in managing hyperglycemia, requiring careful monitoring and intervention focused on achieving stable blood glucose levels.

24) Drug:
In the context of healthcare, 'drug' usually refers to chemical substances used to treat diseases. In this Ayurvedic study, it encompasses herbal formulations and other natural treatments prescribed to manage diabetes and its related health issues.

25) Kara:
Kara refers to hands or limbs in Sanskrit and may symbolize action or the manifestation of symptoms. In the context of this case study, Kara may be relevant in discussing symptoms like numbness or weakness commonly experienced by diabetic patients.

26) Pada:
Pada translates to 'foot' or 'leg,' referring to physical manifestations in the body associated with circulation. In diabetes management, understanding issues related to Pada is essential as complications can lead to neuropathy and increased risk of injury and infection.

27) Daha:
Daha means burning sensation, which is a common symptom in metabolic disorders like diabetes. Recognizing this sign enables practitioners to tailor treatment strategies, addressing not only the underlying condition but also the discomfort experienced by patients.

28) Tiktaghrita (Tiktaghrta, Tikta-ghrita):
Tikta-ghrita refers to a specific preparation of ghee that has bitter properties. It is used therapeutically to balance doshas, particularly in conditions like Madhumeha, as it aids in digestion and detoxification of excess Kapha and Meda.

29) Madhurasyata:
Madhurasyata denotes the sweet taste, associated with heaviness and may aggravate Kapha dosha. Understanding its role in diet is critical when managing diabetes, as excessive intake can contribute to the disease's progression, necessitating careful dietary management.

30) Dhatukshaya (Dhatuksaya, Dhatu-kshaya):
Dhatukshaya refers to the depletion of dhatus (tissues) in Ayurveda, which can lead to weakness and other health complications. Recognizing signs of Dhatukshaya in patients informs a practitioner’s approach, redirecting treatment focus towards restoring essential nutrients and overall vitality.

31) Icchabhedi (Iccha-bhedi):
Icchabhedi refers to a therapeutic concept to suppress or control cravings. In diabetes management, employing Icchabhedi strategies can aid patients in regulating their appetite and food choices, ultimately supporting the overall treatment plan.

32) Discussion:
Discussion encompasses the analysis and interpretation of results obtained from research. It's a critical component in understanding how effective therapy is in altering clinical outcomes, enabling practitioners to refine treatment approaches in managing complex conditions like diabetes.

33) Pravritti (Pravrtti):
Pravritti refers to the onset or drive of symptoms and behaviors. In the context of diabetes, understanding a patient's Pravritti can guide treatment plans, addressing lifestyle habits that contribute to the exacerbation of their condition.

34) Pratiloma (Prati-loma):
Pratiloma translates to the direction against the natural flow. In Ayurveda, it emphasizes the need to restore normalcy and rectify imbalances in bodily functions. Addressing Pratiloma is essential in treating conditions such as diabetes where metabolic flows are disrupted.

35) Substance:
Substance pertains to any material or chemical compound used in treatment. In Ayurveda, various herbal substances and formulations are critically analyzed to determine their impact on health conditions, especially in managing the biochemical processes underlying diseases like diabetes.

36) Ayurveda (Ayus-veda):
Ayurveda is a holistic traditional Indian system of medicine focusing on balance among body, mind, and spirit. It integrates natural therapies, diet, and lifestyle modifications to treat diseases like diabetes, emphasizing preventive care and promoting overall well-being.

37) Haritaki:
Haritaki is an Ayurvedic herb known for its detoxifying and rejuvenating properties. It is often utilized in formulations for managing metabolic disorders, assisting in digestion, and various other health benefits, making it valuable in the context of diabetes management.

38) Abhyanga (Abhyamga):
Abhyanga is a traditional Ayurvedic massage that employs warm oil to nourish the body and promote circulation. This practice may be beneficial in managing symptoms of diabetes by alleviating stress and enhancing circulation, thus promoting overall health.

39) Shodhana (Sodhana):
Shodhana refers to detoxification therapies in Ayurveda aimed at purging excess doshas from the body. It is particularly relevant in managing diabetes, as cleansing treatments like Virechana can help restore metabolic balance and promote the overall well-being of patients.

40) Mridvika (Mrdvika):
Mridvika is a term that may denote specific herbal formulations or concoctions used in Ayurvedic treatments. Its role in detoxification and symptom management emphasizes herbal interventions in holistic care strategies, particularly in conditions like Diabetes.

41) Amasaya (Amashaya, Ama-ashaya):
Amashaya refers to the stomach or primary digestive organ in Ayurveda. Understanding its role helps tailor diets and treatments aimed at enhancing digestion and metabolic functions crucial for managing diabetes and related health conditions.

42) Vitiation (Vitiated):
Vitiated describes an imbalance or disruption in doshas leading to disease. Identifying vitiated states in patients is critical for Ayurveda practitioners to design appropriate therapies that restore balance and support healing in conditions like diabetes.

43) Yogavahin (Yogavahi, Yoga-vahi, Yoga-vahin):
Yogavahi refers to substances that enhance the effects of herbal medicines. This characteristic is particularly important in formulating treatments in Ayurveda, where synergistic interactions are aimed at increasing efficacy, especially relevant in managing metabolic disorders like diabetes.

44) Sukshma (Suksma, Shukshma):
Sukshma translates to subtle or fine, often attributing to qualities of certain substances or interventions. In Ayurveda, it indicates those that can penetrate deeper into bodily tissues, thereby enhancing therapeutic effects, especially in diseases requiring nuanced treatment approaches.

45) Avarana:
Avarana signifies a type of obstruction or covering that prevents normal flow in the body, often due to imbalances in doshas. It is an essential concept to consider in diabetes treatment as it can significantly affect metabolic functions.

46) Svedana:
Svedana refers to sweating techniques used in Ayurvedic treatments for detoxification. This therapeutic approach helps eliminate toxins while improving circulation, thus supporting diabetes management by enhancing metabolic functions and bringing balance to dosha fluctuations.

47) Prakopa:
Prakopa means aggravation or increase of doshas, leading to various health problems. Recognizing Prakopa in a patient is necessary for timely intervention and management strategies, preventing further complications, especially in metabolic disorders like diabetes.

48) Vriddhi (Vrddhi):
Vriddhi denotes increase or growth, which can refer to an excess of doshas or conditions resulting from lifestyle choices. Understanding Vriddhi helps practitioners target weight management and other lifestyle-related factors effectively in diabetes treatment.

49) Tikshna (Tiksna):
Tikshna refers to sharpness or intensity, used to describe certain therapeutic agents that act rapidly to expel morbid doshas. In managing diabetes, Tikshna properties help in addressing excess Kapha and improving digestion.

50) Suptata (Supta-ta):
Suptata signifies numbness or loss of sensation, often experienced by patients with diabetes due to neuropathy. Recognizing and addressing Suptata is crucial in holistic care to mitigate discomfort and improve quality of life.

51) Burning (Burn, Burned, Burnt):
Burning sensation is a common symptom reported by individuals with diabetes, often linked to neuropathy and dysregulated blood sugar levels. Understanding this symptom can help shape comprehensive treatment plans aimed at alleviating discomfort and addressing associated conditions.

52) Svapna:
Svapna translates to sleep or dream in Ayurveda, emphasizing the significance of restful sleep for overall health. In diabetes management, recognizing the impact of sleep quality on metabolic health is crucial for patient recovery and well-being.

53) Dipana:
Dipana refers to the digestive fire or Agni in Ayurveda, essential for proper digestion and metabolism. Enhancing Dipana is critical in managing conditions like diabetes as it regulates energies, enabling better absorption and utilization of nutrients.

54) Kvatha:
Kvatha is a herbal decoction used in Ayurveda, prepared to extract medicinal properties from plants. Its therapeutic applications in the case study highlight the importance of herbal prescriptions tailored to treat conditions like diabetes effectively.

55) Vipaka:
Vipaka refers to the post-digestive effect of food or medications in Ayurveda. Understanding the Vipaka of specific substances is essential in managing diabetes, influencing therapeutic decisions based on the impact of digestion on metabolic processes.

56) Koshna (Kosna):
Koshna refers to warm temperatures that can influence digestion and metabolism. In Ayurvedic dietary recommendations, Koshna qualities are beneficial as they assist in enhancing Agni, vital for managing conditions like diabetes and ensuring effective nutrient absorption.

57) Dushta (Dusta):
Dushta signifies the term 'impure' or 'corrupted' in Ayurvedic context, often referring to morbid doshas or tissues. Identifying Dushta conditions is essential for effective treatment, targeting cleansing and restoring balance to improve health outcomes for metabolic disorders.

58) Ubhaya:
Ubhaya means 'both' in Sanskrit and may refer to dual observations or factors in treatment. In the context of diabetes, understanding Ubha conditions or contributing factors is critical for holistic assessment and effective therapeutic interventions.

59) Phanta (Phamta):
Phanta refers to a specific type of herbal infusion used in Ayurveda. Its utilization underscores the role of custom herbal preparations in therapeutic protocols for managing diabetes, enhancing digestion, and improving overall well-being.

60) Panca (Pancan, Pamca):
Pancha denotes 'five,' often representing the five basic elements or principles in Ayurveda. Understanding Pancha supports the holistic approach to health, emphasizing the interconnection of body, mind, and spirit, especially when addressing complex conditions like diabetes.

61) Pitta:
Pitta is one of the three doshas in Ayurveda, symbolizing heat and transformation. It plays a crucial role in metabolism and digestion. Understanding Pitta imbalances is essential in the management of diabetes, particularly given its interactions with Kapha.

62) Karma (Karman):
Karma translates to action or therapeutic procedures in Ayurveda. The concept emphasizes the importance of intentional and tailored interventions based on individual patient assessments, driving effective strategies in managing diabetes and promoting health.

63) Sneha:
Sneha refers to oleation or the use of fats in Ayurvedic medicine, enhancing the effects of treatment. In diabetes, appropriate Sneha therapies help maintain body balance, supporting metabolic functions and improving patient conditions.

64) Matra:
Matra refers to dosage or quantity in Ayurvedic treatments. Carefully determining Matra is vital for achieving effective results while minimizing risks, as the appropriateness of dosage directly influences patient outcomes in managing conditions like diabetes.

65) Ushna (Usna):
Ushna translates to heat, often associated with stimulating metabolic processes in Ayurveda. Recognizing Ushna properties of certain treatments aids in addressing specific dosha imbalances, especially relevant in therapies targeting excess Kapha in diabetes management.

66) Mutra:
Mutra signifies urine in Ayurveda, often reflecting internal health conditions. Monitoring Mutra changes can provide essential insights into metabolic processes and kidney function, which are crucial in the holistic management of diabetes.

67) Sita (Shita):
Shita translates to cold or coolness in the context of Ayurveda, referring to substances or treatments that reduce heat. Recognizing Shita's role is important for managing conditions aggravated by heat, including symptoms associated with diabetes.

68) Virya:
Virya refers to the potency or strength of herbs in Ayurvedic treatments. Understanding the Virya of substances used in diabetes management can enhance therapeutic effectiveness, informing practitioners on how to achieve optimal health outcomes effectively.

69) Rati:
Rati relates to pleasure or enjoyment, often pertaining to health and well-being. In the context of diabetes, promoting Rati through comprehensive wellness strategies can positively impact patients' mental health and compliance with treatment regimens.

70) Gati:
Gati means movement or flow, which is particularly relevant to bodily processes in Ayurveda. Understanding the Gati of doshas supports effective therapeutic approaches aimed at normalizing functions disrupted by conditions such as diabetes, improving health outcomes.

71) Agni:
Agni refers to digestive fire in Ayurveda, essential for nutrient absorption and metabolic function. Enhancing Agni is critical in managing diabetes, as it influences digestion, energy, and overall health, guiding effective dietary and treatment recommendations.

72) Bala:
Bala translates to strength or immunity in Ayurveda. This concept is crucial in diabetes management, as enhancing a patient's Bala can improve resilience against complications, ultimately leading to better health and quality of life.

73) Vata:
Vata is one of the three doshas in Ayurveda associated with movement and regulation. Vata imbalances can lead to issues tied to nervous system dysfunction and are essential to monitor in diabetes management for optimizing overall health.

74) Vayu:
Vayu represents the air element in Ayurveda, closely related to the Vata dosha. Understanding Vayu's characteristics is vital in addressing issues of movement and circulation, particularly relevant in managing symptoms associated with imbalances in diabetes.

75) Guna:
Guna refers to inherent qualities or attributes of substances in Ayurveda. Understanding the Guna of dietary or herbal components used in treating diabetes highlights their potential effects and contributes to personalized treatment strategies that cater to patient-specific needs.

[Note: The above list is limited to 75. Total glossary definitions available: 81]

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Discover the significance of concepts within the article: �A case study on virechana in sthul madhumeha and its impact on homa ir�. Further sources in the context of Science might help you critically compare this page with similair documents:

Shodhana, Bala, Madhumeha, Abhyanga, Samprapti, Daurbalya, Pachana, Virechana, Chikitsa, Dhatukshaya, Snehapana, Diabetes mellitus, Brimhan Chikitsa, Santarpanjanya Vyadhi, Margavrodh, Kaphaj Prameha, HOMA-IR, Pittaj Prameha.

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