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Antibacterial activity of three source plants of moorva- an invitro study

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Journal name: Ayushdhara
Original article title: Antibacterial activity of three source plants of moorva- an invitro study
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Original source:

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Author(s):

Sevantika Rotti*
Ph.D Scholar, Dept. of Dravyaguna, Alva’s Ayurveda Medical College, Moodbidri, Karnataka
Subrahmanya
Professor & HOD, Dept. of Dravyaguna, Alva’s Ayurveda Medical College, Moodbidri, Karnataka


Ayushdhara:

(A peer-reviewed, bi-monthly open-access journal)

Full text available for: Antibacterial activity of three source plants of moorva- an invitro study

Year: 2019

Copyright (license): CC BY-NC-SA 4.0


Download the PDF file of the original publication


Summary of article contents:

Introduction

The plant Moorva (Jwarahara) is significant in Ayurveda, recognized for its therapeutic properties, particularly in treating fever (Jwara). Various plants have been attributed to Moorva due to confusion stemming from the scarcity and multiple synonyms associated with the term. This study focuses on three species believed to be Moorva—Clematis triloba, Maerua arenaria, and Chonemorpha macrophylla—and evaluates their antibacterial activity through in vitro testing against Gram-positive and Gram-negative bacterial strains. Given the rising issue of antibiotic resistance, exploring the efficacy of natural plant extracts is becoming increasingly important.

Antibacterial Efficacy of Maerua arenaria

A crucial finding of the study is the significant antibacterial potential of the methanolic and aqueous extracts of Maerua arenaria. The study revealed that the methanolic extract of Maerua arenaria exhibited inhibitory activity against Gram-positive bacteria (Staphylococcus aureus) at a concentration of 1000 µg. Additionally, it demonstrated antibacterial properties against Gram-negative bacteria (Escherichia coli) at both 500 µg and 1000 µg concentrations. The aqueous extract was effective at lower concentrations, revealing activity against both bacterial strains at 100 µg. These results underline the relevance of Maerua arenaria as a potential natural antibacterial agent.

Role of Chonemorpha macrophylla

Chonemorpha macrophylla, another plant studied, showed promising activity, particularly against the Gram-negative strain (E. coli) when tested with the methanolic extract at a concentration of 1000 µg. However, the plant did not exhibit significant antibacterial activity against Gram-positive bacteria in this study. This selective effectiveness emphasizes the potential role of Chonemorpha macrophylla in targeting specific bacterial strains, contributing to the need for further investigation into its active compounds and their mechanisms of action.

Conclusion

In conclusion, the study successfully demonstrated the antibacterial properties of Maerua arenaria and Chonemorpha macrophylla, highlighting their potential as natural alternatives to synthetic antibiotics. While Maerua arenaria showed broad-spectrum activity against both Gram-positive and Gram-negative bacteria, Chonemorpha macrophylla's efficacy was limited to Gram-negative strains. The lack of activity from Clematis triloba reinforces the importance of proper plant identification and selection in traditional medicine. Future research should focus on isolating the active compounds from these plants and understanding their mechanisms to pave the way for developing effective natural antibacterial therapies.

FAQ section (important questions/answers):

What is the purpose of the study on Moorva plants?

The study aims to evaluate the antibacterial activity of three Moorva source plants—Clematis triloba, Maerua arenaria, and Chonemorpha macrophylla—using methanolic and aqueous extracts against Gram-positive and Gram-negative bacteria.

Which antibacterial strains were tested in the research?

The research tested the antibacterial activity against Staphylococcus aureus (Gram-positive) and Escherichia coli (Gram-negative) using agar diffusion method with various concentrations of plant extracts.

What were the main findings regarding Maerua arenaria?

Maerua arenaria showed significant inhibitory activity against both Gram-positive and Gram-negative strains, particularly with methanolic extracts at concentrations of 500µg and 1000µg, and 100µg for the aqueous extract.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Antibacterial activity of three source plants of moorva- an invitro study�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Drug:
Drugs, particularly antibacterial drugs, are referenced in the text as curative agents in infectious diseases. The study discusses the antibacterial activity of plant extracts and compares them with standard drugs like Ciprofloxacin to evaluate their efficacy.

2) Aureus:
Staphylococci Aureus is a Gram-positive bacterial strain used in the antibacterial study described in the text. The methanolic and aqueous extracts of various Moorva plants were tested against Staphylococci Aureus to determine their inhibitory activity.

3) Antibiotic (Antibacterial):
The text details an antibacterial study that examines the efficacy of different plant extracts against bacterial strains. Methanolic and aqueous extracts of plants used as Moorva were tested using the Agar diffusion method to identify their anti-bacterial properties.

4) Ayurveda (Ayus-veda):
Ayurveda is a traditional Indian system of medicine that is referenced throughout the text. The study delves into Ayurvedic plants like Moorva, known for their medicinal properties, particularly their Jwarahara (febrifuge) effects, and their antibacterial efficacy.

5) Dravyaguna (Dravya-guna):
Dravyaguna is a branch of Ayurveda that deals with the properties and actions of medicinal plants. The study was conducted by the Dept. of Dravyaguna at Alva’s Ayurveda Medical College, which signifies the academic research context from which the information about the antibacterial activity of Moorva is derived.

6) Karnataka:
Karnataka is a state in India where Alva’s Ayurveda Medical College is located. The research on the antibacterial activity of Moorva plants was conducted in this institution in Karnataka, highlighting the regional context of the study.

7) India:
India is the country where the study was conducted. The research focuses on Ayurvedic plants, which are integral to Indian traditional medicine, and was carried out by scholars at an institution in Karnataka, India.

8) Ashtangahridayasamhita (Astangahrdayasamhita, Ashtanga-hridaya-samhita):
The Ashtanga Hridaya Samhita is a classical Ayurvedic text that is referenced in the study. It explains the disease Jwara and its effects, providing a historical and theoretical background for understanding the therapeutic uses of plants like Moorva in Ayurveda.

9) Ashtangahridaya (Astangahrdaya, Ashtanga-hridaya):
[see source text or glossary: Ashtanga-hridaya-samhita]

10) Discussion:
The discussion section of the text analyses the results of the antibacterial study. It covers the comparison between different extracts' efficiencies, such as how methanolic extract of Maerua arenaria showed significant inhibitory activity, and considers the broader implications of these findings.

11) Ashtanga (Astanga, Ashtan-anga):
[see source text or glossary: Ashtanga-hridaya-samhita]

12) Medicine:
Medicine, in the context of this text, refers to the therapeutic agents derived from Ayurvedic plants. The study explores the medicinal efficacy of Moorva plant extracts as antibacterial agents, contributing to the broader field of pharmacological and medical research.

13) Samhita:
[see source text or glossary: Ashtanga-hridaya-samhita]

14) Hridaya (Hrdaya):
[see source text or glossary: Ashtanga-hridaya-samhita]

15) Disease:
The text discusses the disease condition Jwara as described in Ayurveda, which refers to fever. The antibacterial study conducted aims to find effective Ayurvedic treatments for infectious diseases by testing various plant extracts used traditionally in the treatment of such ailments.

16) Dravya:
Dravya in Ayurveda refers to substances or medicinal herbs that have therapeutic properties. The text mentions Moorva as a Jwarahara dravya, highlighting its use in the treatment of fever and its antibacterial activity investigated in the study.

17) Indian:
The study is based in the Indian context, highlighting traditional Indian medicinal practices such as Ayurveda. The plants tested for antibacterial activity are part of the Indian Ayurvedic system, emphasizing the nation's rich medicinal heritage.

18) Ayus (Ayush):
AYUSH stands for Ayurveda, Yoga & Naturopathy, Unani, Siddha, and Homoeopathy, representing traditional healthcare systems of India. The journal AYUSHDHARA is dedicated to research in AYUSH systems. The study about Moorva plants falls under this category of traditional Indian medicine.

Other Science Concepts:

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Discover the significance of concepts within the article: �Antibacterial activity of three source plants of moorva- an invitro study�. Further sources in the context of Science might help you critically compare this page with similair documents:

Ayurvedic pharmacopoeia, Minimum inhibitory concentration, Inhibitory activity, Aqueous extract, Staphylococcus aureus, Escherichia coli, Antibacterial study, Methanol extract, Agar diffusion method.

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