Assessment of alambushadi churna vs. dwipanchmuladhya tail in amavata.
Journal name: Ayushdhara
Original article title: Clinical assessment of alambushadi churna and dwipanchmuladhya tail vasti in the management of amavata vis-a-vis rheumatoid arthritis
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Sunil Kumar*
Jr 3nd, Dept. of Kayachikita, IMS, B.H.U., Varanasi, Uttar Pradesh
O.P.Singh
Professor, Dept. of Kayachikita, IMS, B.H.U., Varanasi, Uttar Pradesh
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: Clinical assessment of alambushadi churna and dwipanchmuladhya tail vasti in the management of amavata vis-a-vis rheumatoid arthritis
Year: 2019
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Introduction
Amavata, a chronic immune inflammatory disorder akin to rheumatoid arthritis, primarily affects the synovial joints and results from the formation of Ama (toxic residues) in conjunction with vitiated Doshas (biological energies). The rapidly changing dietary habits and lifestyles have exacerbated the prevalence of Amavata, characterized by persistent joint pain, swelling, and stiffness. This study investigates the efficacy of two Ayurvedic formulations, Alambushadi Churna and Dwipanchmuladhya Tail Vasti, in managing Amavata in comparison to conventional treatments like methotrexate. The aim is to establish a scientific basis for these classical Ayurvedic treatments for chronic and acute cases of Amavata.
Efficacy of Ayurvedic Formulations
The study involved a randomized trial with 60 patients diagnosed with Amavata, who were allocated into four groups. Group A received Alambushadi Churna orally, Group B underwent Matra Vasti with Dwipanchmuladhya Tail, Group C combined both treatments, while Group D was administered methotrexate. The study's results highlighted that both Ayurvedic intervention groups, particularly Group C, demonstrated significant improvements in pain reduction, swelling reduction, and overall joint stiffness. The potent herbal ingredients in these formulations, such as Shunthi (ginger) and Guduchi (Tinospora cordifolia), contribute to their efficacy by addressing the underlying Ama and vitiated Vata Dosha.
Benefits of Complementary Therapies
The findings also suggest that the Ayurvedic treatments may have additional benefits on patients鈥� overall wellness. Apart from relieving primary symptoms of joint pain and swelling, Alambushadi Churna and Matra Vasti showed improvements in functional status, such as reduced walking time, better grip strength, and alleviation of other symptoms like Angamarda (body ache) and Alasya (laziness). The combination of these herbs helps in balancing the altered Doshas and promotes the elimination of Ama, facilitating a holistic approach to managing the symptoms of Amavata and enhancing the quality of life for affected patients.
Conclusion
This clinical assessment provides substantial evidence that the integrated application of Alambushadi Churna and Dwipanchmuladhya Tail Vasti in the treatment of Amavata not only matches but can surpass the efficacy of conventional methotrexate therapy in alleviating symptoms and improving functional outcomes. The study emphasizes the need for recognizing and validating traditional Ayurvedic practices within modern medical frameworks, as they not only address the symptoms of Amavata but also its underlying causes. Future research may focus on long-term effectiveness and broader applications of these Ayurvedic treatments, ensuring a multidisciplinary approach to managing chronic inflammatory conditions.
FAQ section (important questions/answers):
What is the primary condition being studied in this clinical assessment?
The primary condition under study is Amavata, which is conceptually linked to Rheumatoid Arthritis. It is described as a chronic immune inflammatory disorder primarily affecting the joints.
What treatments were evaluated in the clinical study?
The study evaluated the efficacy of Alambushadi Churna administered orally and Dwipanchmuladhya Tail Vasti administered through the anus, comparing their effects on Amavata symptoms with a control group treated with Methotrexate.
What were the outcomes measured in the clinical assessment?
Outcomes included clinical assessments of pain, swelling, stiffness, functional capacity, and overall disease activity. Laboratory parameters like Anti-CCP and Rheumatoid Factor levels were also measured to assess treatment effectiveness.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for 鈥淎ssessment of alambushadi churna vs. dwipanchmuladhya tail in amavata.鈥�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Amavata (Ama-vata):
Amavata is a chronic immune inflammatory systemic disorder, resembling Rheumatoid Arthritis, that affects synovial joints due to the formation of Ama, its association with vitiated Dosha, and deposition in Shleshma sthana. Treatment includes Shodhana and Shamana therapies.
2) Varanasi (Varanashi):
Varanasi is a city in Uttar Pradesh, India. It is home to the Institute of Medical Sciences, Banaras Hindu University, where the study on the clinical assessment of Alambushadi Churna and Dwipanchmuladhya Tail Vasti was conducted.
3) Drug:
The study involved the Ayurvedic drugs Alambushadi Churna, a herbal formulation administered orally, and Dwipanchmuladhya Taila used in Matra Vasti therapy, to manage Amavata (Rheumatoid Arthritis) by targeting Ama and vitiated Dosha.
4) Sanskrit:
Sanskrit texts like Chakradatta and Bhavprakash are crucial sources of ancient Ayurvedic formulations used in the study for managing Amavata, including the recipes for Alambushadi Churna and Dwipanchmuladhya Taila.
5) Rheumatoid arthritis:
Rheumatoid arthritis (RA) is an autoimmune disorder that causes chronic inflammation primarily in joints. It correlates with Amavata in Ayurveda, where both conditions share chronicity and inflammation of synovial joints.
6) Medicine:
Medicine in this context refers to both traditional Ayurvedic formulations like Alambushadi Churna and modern drugs like Methotrexate, used for managing symptoms of Amavata vis-脿-vis Rheumatoid arthritis.
7) Swelling:
Swelling in Amavata is due to the predominance of vitiated Doshas, particularly Vata and Kapha. Ayurvedic treatments aim to reduce this swelling through therapies and formulations like Alambushadi Churna.
8) Pain:
Pain in Amavata, similar to Rheumatoid arthritis, results from the chronic inflammation of synovial joints. The study measures pain relief as an outcome of Ayurvedic treatments, showing significant improvement with the study drugs.
9) Disease:
Amavata is a systemic inflammatory disease characterized by chronicity, affecting joints. The etiology involves Ama formation and Dosha vitiation, requiring detailed Ayurvedic management including Shodhana and Shamana therapies.
10) Stiffness:
Joint stiffness in Amavata, akin to Rheumatoid arthritis, is due to the predominance of Vata Dosha. Alambushadi Churna and Matra Vasti with Dwipanchmuladhya Taila aim to alleviate this by pacifying Vata.
11) Kumar:
Dr. Sunil Kumar, affiliated with the Dept. of Kayachikita, IMS, B.H.U., Varanasi, was a part of the research team studying the clinical assessment of Alambushadi Churna and Dwipanchmuladhya Tail Vasti in managing Amavata.
12) Nidana:
Nidana in Ayurveda describes the etiological factors and pathogenesis of diseases like Amavata. Specific tests and symptoms help in diagnosing and managing the condition as per classical texts.
13) Dosha (Dosa):
Dosha refers to the three primary bio-energies (Vata, Pitta, Kapha) in Ayurveda. Imbalance, especially of Vata and Kapha, along with Ama, leads to the development of Amavata.
14) Matra:
Matra refers to a specific measure. In the context of Matra Vasti, it is a measured quantity of medicated oil enema (like Dwipanchmuladhya Taila) used for the treatment of Amavata in Ayurveda.
15) Madhavanidana (Madhava-nidana):
Madhava Nidana is an authoritative Ayurvedic text that details the diagnosis and symptomatology of various diseases, including Amavata. It serves as a significant reference in this study.
16) Madhava:
Madhava, an ancient Ayurvedic scholar, authored Madhava Nidana, a fundamental text for understanding disease etiology, diagnosis, and symptomatology, including Amavata.
17) Madhavakara:
Madhavakara is the author of Madhava Nidana, an essential Ayurvedic text for diagnosing and understanding diseases like Amavata. It provides a detailed clinical description and therapeutic guidelines.
18) Sudarshana (Sudarsana):
Sri Sudarshana Shastri provided commentary on Madhava Nidana, aiding in diagnosing and understanding the etiopathogenesis of diseases like Amavata in the context of Ayurvedic medicine.
19) Vidyotini:
Vidyotini is a commentary on the Ayurvedic text Madhava Nidana by Sri Sudarshana Shastri, providing insights into the diagnosis and management of conditions like Amavata.
20) Virya:
Virya in Ayurveda refers to the potency or efficacy of a drug. For example, Ushna Virya (hot potency) in drugs like Shunthi helps in the Ama Pachana (digestion of toxins) process in Amavata.
21) Vata:
Vata Dosha is one of the three primary bio-energies in Ayurveda, governing movement and communication. An imbalance leads to symptoms like joint stiffness and pain in diseases such as Amavata.
22) Indradeva:
Dr. Indradeva Tripathi edited Chakradatta, an Ayurvedic text referenced in the study for formulations like Alambushadi Churna used in managing Amavata.
23) Ayurveda (Ayus-veda):
Ayurveda is an ancient system of natural medicine from India, focusing on balancing the doshas for health. It provides detailed treatments for diseases like Amavata using therapies and herbal formulations.
24) Taila (Thaila):
Taila refers to oil in Ayurveda. Dwipanchmuladhya Taila is a medicated oil used in Matra Vasti therapy to treat Amavata by pacifying Vata and aiding in detoxification.
25) Ushna (Usna):
Ushna refers to 'hot' potency in Ayurveda. Drugs with Ushna Virya like Shunthi are used to digest Ama and balance Vata and Kapha Doshas in managing Amavata.
26) Shunthi (Sunthi, Sumthi, Shumthi):
Shunthi, or dried ginger (Zingiber officinalis), has Ushna Virya (hot potency) and is used in formulations like Alambushadi Churna to aid in Ama Pachana and reduce pain and stiffness in Amavata.
27) Inflammation:
Inflammation is a key symptom of Amavata and Rheumatoid arthritis. Ayurvedic treatments aim to reduce inflammation using herbal formulations and therapies, including Alambushadi Churna and Matra Vasti.
28) Ramanatha (Ramnath, Rama-natha):
Prof. Ramnath Dwivedy is the editor of Chakradatta, referenced for the preparation of Alambushadi Churna, used in the clinical study for managing Amavata.
29) Trishna (Trsna):
Trishna, or excessive thirst, is a symptom in Amavata due to Vata-Pitta Dosha. Remedies like Lajjalu and Gokshur, which have Shita (cooling) properties, reduce this symptom.
30) Lajjalu:
Lajjalu (Mimosa pudica) is an ingredient in Alambushadi Churna. It possesses Shita (cooling) properties beneficial in treating conditions like Amavata by reducing symptoms like excessive thirst (Trishna).
31) Alasya:
Alasya, or lethargy, is a symptom of Amavata related to Kapha Dosha. Ushna (hot) Virya drugs like Shunthi and Guduchi in Alambushadi Churna help reduce Alasya by balancing Kapha.
32) Aruci:
Aruchi, or lack of appetite, is a symptom of Amavata linked to vitiation of Kapha. Ushna (hot potency) drugs like Shunthi and Vibhitaki in Alambushadi Churna improve appetite and digestive function.
33) Apaka:
Apaka refers to indigestion in Amavata due to Ama Dosha. Ushna Virya (hot potency) drugs like Haritaki, Guduchi, and Trivrit in Alambushadi Churna help digest Ama, improving Apaka.
34) Vatadosha (Vatadosa, Vata-dosha):
Vata Dosha governs movement and causes symptoms like joint stiffness in Amavata when vitiated. Ayurvedic treatments aim to pacify Vata using therapies like Matra Vasti with Dwipanchmuladhya Taila.
35) Vibhitaki:
Vibhitaki (Terminalia bellirica) is an ingredient in Alambushadi Churna. Its Ushna Virya (hot potency) helps in reducing swelling and inflammation in Amavata by balancing Doshas.
36) Angamarda (Anga-marda, Amgamarda):
Angamarda, or body aches, results from Ama in Amavata. Ayurvedic drugs like Amalaki and Vibhitaki in Alambushadi Churna, which have Kapha-hara (anti-Kapha) properties, alleviate Angamarda.
37) Trivrit (Tri-vrit, Trivrt):
Trivrit (Operculina turpethum) possesses Ushna Virya (hot potency) and is used in Alambushadi Churna for its Ama-pachana properties, which help reduce pain and stiffness in Amavata.
38) India:
India is the country where Ayurveda originated and where the study on the clinical assessment of Alambushadi Churna and Dwipanchmuladhya Tail Vasti for Amavata (Rheumatoid Arthritis) was conducted.
39) Tribulus-terrestris:
Tribulus terrestris (Gokshur) is used in Alambushadi Churna for its Vata-pitta-shamak (Vata and Pitta pacifying) properties, making it effective in treating Amavata symptoms like excessive thirst (Trishna).
40) Pittadosha (Pittadosa, Pitta-dosha):
Pitta Dosha governs metabolism and body heat. In Amavata, Pitta imbalance can worsen symptoms like inflammation. Shita (cooling) drugs like Gokshur help manage Pitta-related symptoms.
41) Kaphadosha (Kaphadosa, Kapha-dosha):
Kapha Dosha governs structure and stability. In Amavata, Kapha imbalance leads to heaviness and lethargy. Ushna Virya (hot potency) drugs in Alambushadi Churna reduce Kapha-related symptoms like Alasya.
42) Discussion:
The discussion section in the study evaluates the therapeutic effects of Alambushadi Churna and Matra Vasti on symptoms like pain, swelling, and stiffness in Amavata, providing insights into their effectiveness.
43) Science (Scientific):
The study aims to establish a scientific basis for Ayurvedic formulations like Alambushadi Churna and Dwipanchmuladhya Tail Vasti in managing Amavata, highlighting their clinical efficacy and safety.
44) Amadosha (Amadosa, Ama-dosha):
Ama Dosha refers to toxic, undigested materials in the body, central to the pathology of Amavata. Treatment aims to digest and expel Ama using formulations like Alambushadi Churna.
45) Haritaki:
Haritaki (Terminalia chebula) is a crucial ingredient in Alambushadi Churna, known for its Ushna Virya (hot potency) and Kapha-hara (anti-Kapha) properties, helping alleviate Ama and improve digestion in Amavata.
46) Shodhana (Sodhana):
Shodhana refers to detoxification therapies in Ayurveda. Matra Vasti (oil enema) with Dwipanchmuladhya Taila is a Shodhana therapy used to expel vitiated Doshas and Ama in Amavata.
47) Trivrita (Trivrta):
Trivrit (Operculina turpethum) is a component of Alambushadi Churna with Ushna Virya (hot potency) used to help in Ama Pachana, thereby reducing inflammation and pain in Amavata.
48) Amalaki:
Amalaki (Emblica officinalis) is included in Alambushadi Churna for its medicinal properties. It helps manage Amavata by reducing Ama and balancing Doshas through its therapeutic actions.
49) Pitta:
Pitta is one of the three Doshas governing metabolism and body heat. In Amavata, managing Pitta involves using herbs with Shita (cooling) properties to reduce inflammatory symptoms.
50) Sita (Shita):
Shita refers to 'cooling' properties in Ayurveda. Drugs like Lajjalu and Gokshur with Shita Virya help manage Pitta-related symptoms like excessive thirst in Amavata.
51) Delhi:
Delhi is the location of Chaukhambha Publications, which publishes various Ayurvedic texts referenced in the study, such as Chakradatta and Bhavprakash, providing formulations for treating Amavata.
52) Blood:
Blood tests, including RA and Anti-CCP levels, help diagnose Amavata and assess the effectiveness of treatments like Alambushadi Churna and Matra Vasti, providing objective clinical outcomes.
53) Emblica-officinalis:
Emblica officinalis (Amalaki) is a component of Alambushadi Churna, known for its medicinal properties in Ayurveda, helping reduce Ama and balance Doshas in the treatment of Amavata.
54) Terminalia-chebula:
Terminalia chebula (Haritaki) is an ingredient in Alambushadi Churna, used for its potent therapeutic properties to manage Ama and balance Kapha Dosha in the context of Amavata.
55) Solanum-indicum:
Solanum indicum is an ingredient in Dwipanchmuladhya Taila, an Ayurvedic oil used in Matra Vasti for managing symptoms like joint stiffness and inflammation in Amavata.
56) New-Delhi:
New Delhi, the capital of India, is where publications like Chaukhambha are based, providing Ayurvedic texts referenced for treatments studied in managing Amavata.
57) Stereospermum-suaveolens:
Stereospermum suaveolens (Patalamul) is an ingredient in Dwipanchmuladhya Taila, used in Matra Vasti to reduce inflammation and balance vitiated Doshas in Amavata.
58) Desmodium-gangeticum:
Desmodium gangeticum (Shalparni) is included in Dwipanchmuladhya Taila for its medicinal properties, aiding in the reduction of inflammation and balancing Doshas in Amavata.
59) Terminalia-bellirica:
Terminalia bellirica (Vibhitaki) is used in Alambushadi Churna for its Ushna Virya properties, which help in reducing Kapha-related symptoms like swelling in the treatment of Amavata.
60) Sparshasahatva (Sparsasahatva, Sparshasaha-tva):
Sparsha-asahatva, or tenderness, is a common symptom of Amavata affecting joints. Ayurvedic treatments aim to reduce this tenderness by balancing Doshas and removing Ama.
61) Oroxylum-indicum:
Oroxylum indicum (Sonapatha) is an herb used in Dwipanchmuladhya Taila, a medicated oil utilized in Matra Vasti therapy for the management of inflammation and pain in Amavata.
62) Aegle-marmelos:
Aegle marmelos (Belmultwak) is an ingredient in Dwipanchmuladhya Taila, used for its anti-inflammatory properties to treat symptoms of Amavata in Ayurvedic medicine.
[Note: The above list is limited to 75. Total glossary definitions available: 108]
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