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Clinical study: Bilva Majja vs. Kustumbari in emesis gravidarum.

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Journal name: Ayushdhara
Original article title: A comparative clinical study of bilva majja churna and kustumbari kalka in garbhini chardi w.s.r.to emesis gravidarum
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Author(s):

Indresh Bhasker*
P.G. Scholar, P.G. Department of Prasutitantra and Striroga, National Institute of Ayurveda Madhav Vilas Palace, Jorawar Singh Gate, Amer Road, Jaipur
Sandhya Rav
Ph.D Scholar, P.G. Department of Prasutitantra and Striroga, National Institute of Ayurveda Madhav Vilas Palace, Jorawar Singh Gate, Amer Road, Jaipur
B. Pushpalatha
Associate Professor, P.G. Department of Prasutitantra and Striroga, National Institute of Ayurveda Madhav Vilas Palace, Jorawar Singh Gate, Amer Road, Jaipur
K. Bharathi
Professor & HOD, P.G. Department of Prasutitantra and Striroga, National Institute of Ayurveda Madhav Vilas Palace, Jorawar Singh Gate, Amer Road, Jaipur


Ayushdhara:

(A peer-reviewed, bi-monthly open-access journal)

Full text available for: A comparative clinical study of bilva majja churna and kustumbari kalka in garbhini chardi w.s.r.to emesis gravidarum

Year: 2018

Copyright (license): CC BY-NC-SA 4.0


Download the PDF file of the original publication


Summary of article contents:

Introduction

Pregnancy involves significant physiological and hormonal changes that can lead to various minor ailments in women, most notably nausea and vomiting, collectively termed Garbhini chardi in Ayurvedic medicine. Emesis gravidarum, a more severe form of pregnancy-related nausea, can negatively impact a woman's quality of life if not managed effectively. This study aimed to compare the clinical efficacy of two Ayurvedic formulations�Bilva majja churna combined with Lajambu, and Kustumbari kalka mixed with Tandulodaka and Sharkara—in treating Garbhini chardi among pregnant women.

Efficacy of Bilva Majja Churna

The study revealed that the group receiving Bilva majja churna with Lajambu (Group-A) experienced a significantly greater average relief from symptoms compared to the second group receiving Kustumbari kalka with Tandulodaka (Group-B). Specifically, Group-A reported an average percentage of relief of 71.66%, with the highest relief observed in fatigue (88.89%) and anorexia (78.57%). The therapeutic effects include the anti-emetic properties of Bilva majja churna, which is well-regarded in Ayurveda for its ability to pacify Vata and Kapha doshas, thereby alleviating nausea and vomiting.

The Role of Kustumbari Kalka

While Group-B, which received Kustumbari kalka, also showed significant improvements with an average percentage of relief of 60.39%, the results were notably less pronounced than those of Group-A. The constituents of Kustumbari kalka, particularly Dhanyaka (Coriandrum sativum), possess properties that target gastrointestinal dysmotility and vitiated Vata, which are implicated in nausea and vomiting during pregnancy. Although Kustumbari kalka demonstrated its effectiveness in alleviating symptoms, it did not reach the same level of efficacy as the Bilva majja churna formulation.

Conclusion

In conclusion, both Ayurvedic formulations proved effective in managing Garbhini chardi and its associated symptoms, with Bilva majja churna combined with Lajambu yielding better results in symptom relief. The study underscores the potential of Ayurvedic treatments as a safe and effective means of addressing the common and debilitating symptoms of nausea and vomiting during pregnancy. Further research may be warranted to explore these formulations' broader applications and enhance treatment strategies for pregnant women experiencing similar ailments.

FAQ section (important questions/answers):

What is the main focus of this clinical study?

The study evaluates the effectiveness of Ayurvedic treatments, specifically Bilva majja churna with Lajambu and Kustumbari kalka with Tandulodaka, in managing Garbhini chardi or emesis gravidarum in pregnant women.

What were the key findings regarding patient relief?

Both treatments showed significant improvement, with Group-A receiving Bilva majja churna achieving an average relief of 71.66%, while Group-B with Kustumbari kalka showed 60.39% relief, indicating that Bilva majja churna was comparatively more effective.

What criteria were used for including patients in the study?

Participants included were pregnant women diagnosed with Garbhini chardi in the first trimester, with exclusions for conditions like hyperemesis gravidarum, second or third-trimester vomiting, or vomiting due to systemic disorders.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Clinical study: Bilva Majja vs. Kustumbari in emesis gravidarum.�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Chardi:
Chardi refers to vomiting, a condition where the body expels stomach contents through the mouth. In the context of the study, it is a common symptom experienced by pregnant women and a focal point of treatment evaluation.

2) Vomiting:
Vomiting, also known as Chardi, is the forcible voluntary or involuntary emptying of stomach contents through the mouth, and it is a symptom addressed in the treatment of Emesis gravidarum in pregnant women.

3) Nausea:
Nausea is a sensation of unease and discomfort in the stomach with an urge to vomit. It is a primary symptom in the study of treatments for Emesis gravidarum among pregnant women.

4) Garbhini:
Garbhini refers to pregnancy. 'Garbhini chardi' specifically denotes the nausea and vomiting during pregnancy, a central issue addressed by the Ayurvedic treatments in the study.

5) Kalka:
Kalka is a term for a paste in Ayurveda used for medicinal purposes. In the study, Kustumbari kalka is tested for its efficacy in treating vomiting during pregnancy.

6) Majja:
Majja in Ayurveda refers to the marrow or pith of fruits or bones. Bilva majja, specifically, is the fruit pulp used in the study to evaluate its therapeutic benefits during pregnancy-related nausea and vomiting.

7) Drug:
Drugs in this study refer to Ayurvedic formulations like Bilvaphala majja churna and Kustumbari kalka, evaluated for their effectiveness in treating pregnancy-related nausea and vomiting.

8) Bilva (Vilva):
Bilva, scientifically known as Aegle marmelos, is used in Ayurvedic medicine for its therapeutic properties. Bilva majja churna is one of the trial drugs evaluated in this study.

9) Sharkara (Sarkara):
Sharkara is Ayurvedic terminology for sugar. In the study, it is mixed with Tandulodaka in Group-B treatment to manage nausea and vomiting in pregnant women.

10) Pregnant:
Pregnant women, referred to as Garbhini in Ayurveda, are the primary subjects in this study, experiencing Emesis gravidarum characterized by nausea and vomiting.

11) Tandulodaka (Tandula-udaka):
Tandulodaka is rice water, used as an anupana (vehicle) for administering the Kustumbari kalka along with Sharkara in the management of Emesis gravidarum.

12) Ayurveda (Ayus-veda):
Ayurveda is the ancient Indian system of medicine. The study employs Ayurvedic formulations to treat nausea and vomiting in pregnant women, thereby exploring traditional wisdom for modern clinical application.

13) Madhura:
Madhura, meaning 'sweet', is a taste (Rasa) in Ayurveda known for its soothing and balancing properties, widely used in formulations to alleviate symptoms like nausea and vomiting.

14) Vata:
Vata is one of the three doshas in Ayurveda, representing movement and air. Its vitiation is often implicated in digestive disturbances such as vomiting (Chardi), which the study aims to treat.

15) Rice (Rce):
Rice, especially when parched as Laja, is used in Ayurvedic formulations. Laja mixed in water (Tandulodaka) serves as a vehicle in the study to treat pregnancy-related vomiting.

16) Bilvaphala (Bilva-phala):
Bilvaphala refers to the fruit of the Bilva tree (Aegle marmelos). In the study, Bilvaphala majja churna is used for its anti-emetic properties to treat nausea and vomiting in pregnant women.

17) Habitat:
Habitat refers to the living environment of patients. The study shows that a majority of subjects were from urban habitats, affecting lifestyle factors like diet and access to healthcare.

18) Rasa (Rasha):
Rasa, or taste, is a fundamental concept in Ayurveda affecting the balance of doshas. The study employs drugs with specific Rasa like Madhura and Kashaya to manage symptoms effectively.

19) Food:
Food and its properties are crucial in Ayurveda, particularly in pregnancy. The study leverages rice-based formulations (Laja, Tandulodaka) to provide nutrients and balance for pregnant women.

20) Madhurarasa (Madhura-rasa):
Madhura-rasa denotes the sweetness taste in Ayurvedic medicine, known for its nutritious, balancing, and healing qualities, essential in the formulations used in this study for treating Emesis gravidarum.

21) Striroga (Stri-roga):
Striroga refers to diseases related to women. The department involved in the study specializes in Prasutitantra (Obstetrics) and Striroga (Gynecology), focusing on conditions like Emesis gravidarum.

22) Vipaka:
Vipaka refers to the post-digestive effect of a substance in Ayurvedic medicine. For instance, Bilva majja is mentioned as having Katu vipaka, influencing its therapeutic effects.

23) Kapha:
Kapha is one of the three doshas in Ayurveda, representing earth and water principles. The study treatments aim to balance Kapha to alleviate symptoms of nausea and vomiting in pregnant women.

24) Guna:
Guna refers to qualities like heaviness, lightness, or coldness in Ayurvedic substances. These are crucial in the study to design formulations that pacify the doshas causing nausea and vomiting.

25) Snigdha:
Snigdha is a quality in Ayurveda meaning 'unctuous' or 'oily'. For instance, Sharkara has Snigdha guna, making it suitable for treating dryness and balancing Vata and Pitta in the study.

26) Samaka (Shamaka):
Shamaka means something that pacifies or alleviates. In the context of the study, the formulations are intended to have Shamaka properties for balancing Vata and Kapha doshas.

27) Kashaya (Kasaya):
Kashaya, or astringent taste, is used in Ayurveda to balance Pitta and Kapha doshas. Bilva has Kashaya rasa, which helps in treating Emesis gravidarum by controlling vomiting and nausea.

28) Disease:
Disease refers to any abnormal condition affecting the body. The study focuses on managing the disease condition Emesis gravidarum through Ayurvedic treatment protocols.

29) Garbha:
Garbha means fetus or embryo. The study focuses on Garbhini chardi, which involves nausea and vomiting during the crucial stage of carrying a Garbha.

30) Hridya (Hrdya):
Hridya means 'heart-friendly' in Ayurveda. The formulations used in the study are described as Hridya, indicating their nourishing and soothing effects that benefit both the mother and the fetus.

31) Jaipur:
Jaipur is the location of the National Institute of Ayurveda where the study was conducted. It provided the setting and patient population for the clinical trials.

32) Labour (Labor):
Labour class mentioned in the study refers to the socioeconomic background of some patients. It helps understand the variation in disease presentation and treatment accessibility.

33) Laja:
Laja refers to parched rice used in Ayurvedic formulations for its light and easily digestible properties. In this study, it's used with Bilva majja churna for treating Emesis gravidarum.

34) Irritation:
Irritation, especially in the digestive tract, can contribute to symptoms like nausea and vomiting. The study aims to alleviate such irritation through Ayurvedic treatments.

35) Vitiation (Vitiated):
Vitiation refers to the disturbance of doshas (Vata, Pitta, Kapha) in Ayurveda, leading to diseases. The study addresses Vata and Kapha vitiation contributing to Emesis gravidarum.

36) Brimhana (Brmhana):
Brimhana refers to nourishing therapies in Ayurveda. The instruments used in this study aim to provide Brimhana benefits to pregnant women, improving overall health and preventing nausea and vomiting.

37) Hrillasa (Hrllasa):
Hrillasa is the term for nausea in Ayurveda. The study assesses treatments aimed at reducing Hrillasa or the feeling of unease in pregnant women experiencing Emesis gravidarum.

38) Mineral:
Minerals are essential nutrients provided by formulations used in the study, such as Tandulodaka mixed with Sharkara, to support the health of pregnant women and their fetuses.

39) Nature:
Nature refers to both the inherent qualities (guna) of substances and the natural state of pregnant women. The study respects these by using naturally-derived Ayurvedic formulations.

40) Laghu:
Laghu means 'light' in the context of properties or qualities in Ayurveda. Bilva, used in the study, has Laghu guna, making it suitable for treating nausea and vomiting by balancing doshas without heavy digestion.

41) Udana:
Udana is one of the five subtypes of Vata dosha, responsible for upward movement. Its imbalance can lead to vomiting (Chardi), addressed by the formulations used in the study.

42) Ushna (Usna):
Ushna refers to heat in Ayurveda. Some treatments in the study have Ushna veerya (potency), crucial for balancing cold-related conditions like certain types of nausea and vomiting.

43) India:
India is the country where the study was conducted, specifically utilizing traditional Ayurvedic practices and principles to explore effective treatments for pregnancy-related conditions.

44) Balya:
Balya substances in Ayurveda are those that provide strength and nourishment. Treatments in the study aim to be Balya, enhancing the health of pregnant women and their fetuses.

45) Sita (Shita):
Sita means cold in Ayurveda. For instance, Sharkara used in the study has Sita veerya, providing a cooling effect which is beneficial for treating Pitta-related nausea and vomiting.

46) Vila:
[see source text or glossary: Vila]

47) Aegle marmelos:
Aegle marmelos, scientific name for Bilva, is used extensively in the study for its anti-emetic properties to treat nausea and vomiting in pregnant women experiencing Emesis gravidarum.

48) Antibiotic (Antibacterial):
Anti-bacterial properties, like those in Bilva, help in treating infections that might cause or worsen vomiting. This is one rationale for selecting Bilva majja churna in the study.

49) Madhavanidana (Madhava-nidana):
Madhavanidana is an ancient Ayurvedic text that describes etiologies and symptoms of various diseases, including those treated in the study, providing a traditional basis for symptom management.

50) Tridoshahara (Tridosahara, Tridosha-hara):
Tridoshahara substances balance all three doshas (Vata, Pitta, Kapha). Kustumbari kalka, used in the study, has Tridoshahara properties, making it effective for treating Emesis gravidarum.

51) Kaphadosha (Kaphadosa, Kapha-dosha):
Kapha-dosha represents earth and water elements in Ayurveda. The study addresses Kapha-related symptoms like nausea and vomiting using appropriate formulations to achieve balance.

52) Udanavata (Udana-vata):
Udana-vata is a subtype of Vata responsible for upward movements, including vomiting. The formulations used in the study aim to pacify Udana-vata to alleviate vomiting in pregnant women.

53) Discussion:
Discussion refers to the analysis of the study results. Here, the efficacy, comparative analysis, and therapeutic rationales of the Ayurvedic treatments for Emesis gravidarum are discussed.

54) Pittahara (Pitta-hara):
Pittahara refers to substances that pacify Pitta dosha. Treatments in the study, like cooling Sharkara and Laja, have Pittahara properties, making them suitable for managing nausea and vomiting.

55) Vatapitta (Vata-pitta):
Vatapitta imbalance involves the combined vitiation of Vata and Pitta doshas. The study uses formulations to address this imbalance, effectively treating symptoms like Chardi and Hrillasa.

56) Vibandha:
Vibandha means constipation, a common associated symptom in pregnant women experiencing Emesis gravidarum. The study observes the impact of Ayurvedic treatments on Vibandha.

57) Dhanyaka:
Dhanyaka, or coriander (Coriandrum sativum), is used in Kustumbari kalka. Its tridoshahara properties help manage digestive issues and nausea, as explored in the study.

58) Kashyapa (Kasyapa, Kashya-pa, Kashyapanamdana):
Kashyapa is an ancient sage and author of an Ayurvedic text that provides insights into the management of pregnancy-related conditions, including vomiting, guiding the treatments used in the study.

59) Bharathi:
Bharathi, mentioned as one of the authors, contributed to the study on the effectiveness of Ayurvedic treatments for Emesis gravidarum at the National Institute of Ayurveda, Jaipur.

60) Upadrava:
Upadrava refers to complications or secondary conditions in Ayurveda. The study considers vomiting (Chardi) as an Upadrava during pregnancy, addressing it with specific treatments.

61) Dauhrida (Dauhrda):
Dauhrida means 'dual-hearted', referring to the pregnant state. Vomiting caused by the desires or needs of the Dauhrida is addressed in the study through Ayurvedic formulations.

62) Agantuja (Agantu-ja):
Agantuja Chardi refers to external or incidental causes of vomiting. In the study, this category is considered under the broader scope of Emesis gravidarum and treated accordingly.

63) Samgrahin (Sangrahi, Samgrahi):
Samgrahi means 'absorbent' in Ayurveda. Bilva majja used in the study has Samgrahi properties, helping to absorb excess fluids and balance the digestive system during pregnancy.

64) Tandula (Tamdula):
Tandula refers to rice. In the study, rice water (Tandulodaka) is used as a medium for administering treatments, leveraging the nutritional benefits and easing digestive issues.

65) Sandhya (Shandhya, Samdhya):
Sandhya, mentioned as one of the authors, is involved in the study to evaluate the clinical efficacy of Ayurvedic treatments for managing Emesis gravidarum.

66) Anupana:
Anupana refers to a vehicle or carrier substance for administering Ayurvedic medicine. Tandulodaka is used as an Anupana in the study to enhance the benefits of Kustumbari kalka.

67) Anurasa:
Anurasa means 'secondary taste'. For instance, rice has a Madhura (sweet) primary taste and Kashaya (astringent) anurasa, both of which are considered in formulating treatments in the study.

68) Doshaja (Dosha-ja, Dosaja):
Doshaja refers to conditions caused by the vitiation of doshas. The study focuses on managing vomiting due to Doshaja factors like Vata and Kapha imbalance through Ayurvedic treatments.

69) Ruksha (Ruksa):
Ruksha means 'dry' in Ayurveda. Bilva majja has Ruksha guna, which helps in reducing the symptoms of Chardi associated with Kapha by drying up excess moisture.

70) Harita:
Harita is an ancient Ayurvedic author who described ailments affecting pregnant women. His work informs the understanding of conditions like Garbhini chardi treated in the study.

71) Shrama (Srama):
Shrama means fatigue, a common associated complaint in pregnant women experiencing vomiting. The study measures the effectiveness of treatments in alleviating Shrama.

72) Desire:
Desire in the context of the study refers to nutritional cravings or aversions in pregnant women. These are factored into designing effective Ayurvedic treatments to reduce vomiting.

73) Aruci:
Aruchi means anorexia or loss of appetite. The study tracks Aruchi as a primary symptom associated with vomiting in pregnant women and assesses the effectiveness of treatments in improving this condition.

74) Dosha (Dosa):
Dosha refers to the three fundamental bodily bio-elements in Ayurveda: Vata, Pitta, and Kapha. The study aims to balance these doshas to treat vomiting and nausea in pregnant women.

75) Pitta:
Pitta is one of the three doshas, representing heat and metabolism. The study employs Pittahara treatments to balance Pitta, thereby reducing vomiting and nausea in pregnant women.

[Note: The above list is limited to 75. Total glossary definitions available: 89]

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Discover the significance of concepts within the article: �Clinical study: Bilva Majja vs. Kustumbari in emesis gravidarum.�. Further sources in the context of Science might help you critically compare this page with similair documents:

Pregnancy, Nausea and vomiting, Inclusion criteria, Exclusion criteria, Ayurvedic formulation, Randomized Trial, Ethical Clearance, Statistical Significance, Comparative clinical study, Clinical efficacy, Dietary intervention, Associated complaints, Dietary supplement, First trimester, Intervention model, Garbhini Chardi, Emesis Gravidarum.

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