Antibiogram and GC analysis of Euphorbia hirta leaf extract
Journal name: Ancient Science of Life
Original article title: Antibiogram and GC analysis of Euphorbia hirta leaf extract
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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V. Shanmugaraju, P. Chidambara Rajan, N Abirami, K. Rajathi
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Antibiogram and GC analysis of Euphorbia hirta leaf extract
Year: 2007
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
The study investigates the antibacterial properties of the leaf extract of Euphorbia hirta, a plant known for its therapeutic uses and common in various habitats across India. With the rising global concern regarding resistance to antimicrobial agents, there is a pressing need to explore plant-derived remedies as potential alternatives. The research specifically examines the efficacy of both ethanolic and aqueous extracts of E. hirta, with an objective to analyze their antibacterial activity and identify active components through Gas Chromatography (GC).
Active Component Identification
The results indicate that the ethanolic extract of Euphorbia hirta demonstrates significant antibacterial activity, particularly against E. coli and Staphylococcus aureus, with inhibition zones measured. While both extracts inhibited the growth of E. coli, the ethanolic extract exhibited superior efficacy against other pathogens, including Klebsiella pneumonia and Pseudomonas aeruginosa, which showed no response to the aqueous extract. Notably, the GC analysis of the ethanolic extract revealed the presence of citronellal, a compound that could contribute to the observed antibacterial properties, suggesting that the active principles in plant extracts are essential in determining their medicinal effectiveness.
Conclusion
In conclusion, the study highlights the promising antibacterial potential of ethanolic extracts of Euphorbia hirta, especially in combating various microbial strains. The identification of citronellal through GC analysis points towards the need for further research to explore the full spectrum of active compounds and their specific roles in antimicrobial activity. This work underscores the importance of investigating plant-based remedies as viable solutions in addressing the growing challenge of antibiotic resistance.
FAQ section (important questions/answers):
What was the main focus of the study on Euphorbia hirta?
The study focused on determining the antibiogram activity of ethanolic and aqueous extracts of Euphorbia hirta, as well as identifying any active principles through Gas Chromatography analysis.
Which bacterial strains were tested against Euphorbia hirta extracts?
The extracts were tested against E. coli, Klebsiella pneumonia, Proteus species, Pseudomonas aeruginosa, Salmonella typhi, Staphylococcus aureus, and Streptococcus species using a well-diffusion method.
What were the findings regarding the antibacterial activity?
The ethanolic extracts exhibited greater antibacterial activity compared to the aqueous extracts. Specifically, the ethanol extract effectively inhibited the growth of Staphylococcus aureus and other bacteria.
What compound was identified in the ethanolic extract through GC analysis?
Gas chromatography analysis revealed the presence of citronellal in the ethanolic extract, which may be responsible for its antibacterial activity.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for 鈥淎ntibiogram and GC analysis of Euphorbia hirta leaf extract鈥�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Activity:
The keyword 'Activity' refers to the functional or biological processes demonstrated by a substance. In this context, it relates specifically to the antimicrobial actions of the extracts from Euphorbia hirta, which were assessed through antibiogram assays. The study focuses on evaluating how effective these extracts are against various bacterial strains.
2) Antibiotic (Antibacterial):
The keyword 'Antibiotic' refers to drugs specifically designed to combat bacterial infections. The study highlights the increasing resistance to antibiotics and explores plant-based alternatives like Euphorbia hirta, which may offer a promising solution in light of growing concerns over traditional antibiotic efficacy.
3) Discussion:
The section labeled 'Discussion' encompasses the analysis of results obtained from experiments. It is where researchers interpret findings, compare them to existing literature, and suggest implications. In this study, the discussion emphasizes the comparative efficacy of the extracts, providing insights into the plant's role in antimicrobial activities.
4) Ayurveda (膧yurveda, Ayus-veda):
The term 'Ayurveda' is significant here as it denotes a traditional system of medicine originating from India, which often utilizes plants for therapeutic purposes. The study connects the use of Euphorbia hirta, a common plant in Ayurvedic practices, showcasing its relevance in both historical contexts and modern medicinal research.
5) Medicine:
The word 'Medicine' serves as a broad term covering any substance used for treating, preventing, or diagnosing disease. In this study, the exploration of Euphorbia hirta reflects an emphasis on natural and herbal remedies, underlining the plant's historical and contemporary significance in healthcare.
6) Science (Scientific):
The keyword 'Science' indicates the systematic study of the natural world through observation and experimentation. The study employs scientific methodologies to evaluate the antibacterial properties of plant extracts, underscoring the importance of empirical research in validating traditional medicinal practices and discovering new therapeutic agents.
7) Vijaya (Vijay膩):
The name 'Vijaya' in the references denotes an author who contributed to relevant studies on Euphorbia hirta. Citing authors like Vijaya highlights the collaborative nature of scientific research, where previous studies build a foundation for new investigations, enriching the literature surrounding the plant's medicinal properties.
8) Kambu (Kamb奴):
The term 'Kambu' refers to another author in the references list. Such names represent the collaborative efforts in the field of ethnopharmacology, where various researchers contribute their findings to enhance the understanding of traditional plants and their applications in modern medicine, including Euphorbia hirta.
9) Water:
The keyword 'Water' signifies the solvent used in extracting bioactive compounds from Euphorbia hirta. The study compares aqueous and ethanolic extracts, demonstrating the relevance of different solvent polarities in extracting varying levels of antibacterial activity, which informs researchers about optimal extraction methods for therapeutic uses.
10) Rice (峁歝e):
The term 'Rice' appears in the introduction as part of a description of the natural habitat of Euphorbia hirta. This contextual relevance provides insight into the plant's availability and its prominence in agricultural settings, reinforcing the accessibility of traditional medicines derived from readily available plants.
11) Drug:
The term 'Drug' encompasses any substance that alters physiological processes in the body. In the study, the focus is on identifying potential drug candidates from natural sources like Euphorbia hirta, exploring how plant-derived compounds can contribute to modern pharmacology and address issues like antimicrobial resistance.
12) Inci (I帽ci, Imci, Inc墨):
The term 'Inch' mentions measurement units in the context of the GC analysis setup. Although primarily a unit of length, its inclusion underscores the precision required in scientific experimentation, particularly when evaluating dimensions of chromatographic columns, which is essential for accurate and replicable results in research.
Other Science Concepts:
Discover the significance of concepts within the article: 鈥�Antibiogram and GC analysis of Euphorbia hirta leaf extract鈥�. Further sources in the context of Science might help you critically compare this page with similair documents:
Euphorbia hirta, Active principle, Antibacterial activity, Therapeutic purpose, Zone of inhibition, Aqueous extract, Staphylococcus aureus, Ethanolic extract, Pseudomonas aeruginosa, Well diffusion method, Gas chromatography, Salmonella Typhi, Klebsiella pneumonia, Multiple Drug Resistance, Crude extract, Proteus species, Department of Biochemistry, Department of Biotechnology, Medicinal shop.