Significance of Sustained release formulation
Sustained release formulation is a type of drug delivery system designed to release the active ingredient slowly over an extended period, providing prolonged therapeutic effects. These formulations aim to maintain consistent drug levels in the bloodstream, improving both therapeutic effectiveness and patient adherence. By controlling the rate of release, sustained release formulations can reduce the frequency of dosing compared to instant release forms, ultimately enhancing the overall efficacy of the treatment and minimizing spikes in drug concentration.
Synonyms: Controlled release formulation, Extended release formulation, Timed release formulation, Sustained action formulation, Controlled release, Extended release, Prolonged release, Modified release, Delayed release
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The concept of Sustained release formulation in scientific sources
Sustained release formulation is a drug delivery system that provides controlled, prolonged release of medication, maintaining consistent drug levels in the body and improving therapeutic effects while reducing dosing frequency over time.
From: The Malaysian Journal of Medical Sciences
(1) These are drug formulations that can result in gastric pharmacobezoar formation in cases of slow-release theophylline overdose, where the residue of the formulation can result in fatality.[1]