SOP development for Ras Pottali per Rasa Prakasha Sudhakara
Journal name: Ayushdhara
Original article title: Development of standard operative procedure for ras pottali w.r.s. rasa prakasha sudhakara
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Vijay Shree Bharti
PG scholar, P.G. Department of Rasashastra & Bhaishajya Kalpana, National Institute of Ayurveda, Jaipur, Rajasthan, India.
Rajendra Barfa
PG scholar, P.G. Department of Rasashastra & Bhaishajya Kalpana, National Institute of Ayurveda, Jaipur, Rajasthan, India.
Amit Mishra
PG scholar, P.G. Department of Rasashastra & Bhaishajya Kalpana, National Institute of Ayurveda, Jaipur, Rajasthan, India.
Sakhitha K.S.
Lecturer, P.G. Department of Rasashastra & Bhaishajya Kalpana, National Institute of Ayurveda, Jaipur, Rajasthan, India.
K. Shankar Rao
Professor & HOD, P.G. Department of Rasashastra & Bhaishajya Kalpana, National Institute of Ayurveda, Jaipur, Rajasthan, India.
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: Development of standard operative procedure for ras pottali w.r.s. rasa prakasha sudhakara
Year: 2020 | Doi: 10.47070/ayushdhara.v7i6.662
Copyright (license): CC BY-NC-SA 4.0
Download the PDF file of the original publication
Summary of article contents:
Introduction
The study presented focuses on developing a Standard Operating Procedure (SOP) for the preparation of "Rasa Pottali," a specific herbo-mineral formulation in the Ayurvedic medical system, as referenced in "Rasa Prakasha Sudhakara." "Rasashastra," the branch of Ayurveda dealing with metal and mineral-based medicines, plays a crucial role in ensuring effective treatment through quality formulations. The study notes that many traditional Rasa formulations are either lost or poorly understood, emphasizing the need for standardized quality profiles. The research aims to create three different experimental formulations of Rasa Pottali, exploring manufacturing processes and evaluating potential modifications.
Importance of Purification Methods in Rasa Pottali Preparation
One key aspect of the study is the purification processes of the primary ingredients, namely Parada (mercury) and Gandhaka (sulfur). The Shodhana (purification) of Parada was done using Sudha (calcium oxide), bringing about a color change that suggests successful removal of impurities through a reduction reaction. A total weight loss of 14.7% during this process highlights the effectiveness of the purification method. Additionally, the purification of Gandhaka involved using milk and ghee, substances known to counterbalance Pitta aggravation while enhancing Rasayana (rejuvenation) properties. The post-purification evaluation revealed that both Parada and Gandhaka achieved desirable attributes, critical for formulation efficacy.
Variations in Rasa Pottali Preparation Techniques
The preparation of Rasa Pottali was executed in three distinct samples—RP 1, RP 2, and RP 3—each employing different methods of incorporating Bhavana (literally "to infuse" or "to soak") and Lepana (coating). The formulation's composition was modified by varying the Bhavana and Lepana techniques, showcasing the research's adaptability in pharmaceutical preparation. The final heating process, referred to as Paka, was carefully monitored, maintaining temperatures between 322°C and 520°C for 36 hours. These controlled environments during manufacturing are crucial for ensuring the quality and uniformity of the final product.
Conclusion
The study concludes by affirming the necessity for establishing a standardized protocol for preparing Rasa Pottali, allowing for greater reliability and safety in therapeutic applications. The innovative modifications to the classic preparation methods were aimed at enhancing the formulation's overall efficacy while adhering to Ayurvedic principles. Additionally, the research underscores the importance of further clinical studies to establish safety profiles and therapeutic efficacy for Rasa Pottali, advocating for its acceptance in modern Ayurvedic practice. Through these efforts, the research not only enriches the understanding of Rasashastra but also helps in preserving ancient knowledge while adapting to contemporary contexts.
FAQ section (important questions/answers):
What is Ras pottali and its significance in Ayurveda?
Ras pottali is a herbo-mineral preparation in Rasashastra, a key branch of Ayurveda. It utilizes Mercury and other ingredients for therapeutic applications and aims to enhance the quality and efficacy of Ayurvedic treatments.
What are the key steps involved in preparing Ras pottali?
The preparation involves several steps including Shodhana (purification) of Parada and Gandhaka, preparation of Kajjali, creating Parpati, and finally shaping the Pottali. Each step ensures quality and efficacy in the final product.
What modifications were made in the traditional preparation of Ras pottali?
Modifications included using Kalka for application instead of Dhatura patra swarasa on cloth. The study detailed variations in shaping methods and examined the effects of temperature and duration during the Paka process in Bhudhara puta.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “SOP development for Ras Pottali per Rasa Prakasha Sudhakara�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Pottali:
Pottali is a form of Ayurvedic medicine preparation where the ingredients are processed and shaped into a compact form, often used in critical care. This form is significant in Rasashastra for its therapeutic applications and ease of use [see source text or glossary: Pottali].
2) Rasa (Rasha):
Rasa refers to mercurial preparations in Ayurveda, which play a vital role in therapeutic applications. It involves combining metals, minerals, and plant materials to create effective medicines [see source text or glossary: Rasa].
3) Parada:
Parada, or mercury, is a critical ingredient in Rasashastra. The processes of Shodhana (purification) and Bhavana (levigation) are essential to detoxify Parada and make it suitable for medicinal use [see source text or glossary: Parada].
4) Lepa:
Lepa refers to the external application or coating of herbal pastes. Dhatura patra kalka was used as a Lepa in preparing Rasa pottali, enhancing bonding among the ingredients through various chemical changes [see source text or glossary: Lepa].
5) Bhavana (Bha-vana):
Bhavana is a process of trituration with herbal juices used to reduce particle size and integrate active principles into the formulation. In the study, Tamboola patra swarasa and Dhatura patra swarasa were used for Bhavana [see source text or glossary: Bhavana].
6) Gandhaka (Gamdhaka):
Gandhaka, or sulfur, undergoes Shodhana (purification) to remove impurities and enhance its medicinal properties. In this study, Gandhaka was processed using Godugdha (cow’s milk) and ghee [see source text or glossary: Gandhaka].
7) Parpati:
Parpati is a specific Ayurvedic preparation involving the melting and shaping of Kajjali. It serves as a base for making Pottali formulations like Rasa pottali, which have significant therapeutic applications [see source text or glossary: Parpati].
8) Kalka:
Kalka refers to herbal pastes used in various Ayurveda formulations. In the preparation of Rasa pottali, Dhatura patra kalka was used for Lepana (coating) over the Pottali, aiding in the bonding of ingredients [see source text or glossary: Kalka].
9) Shodhana (Sodhana):
Shodhana is the process of purification and detoxification of metals and minerals, making them suitable for medicinal use. For example, Parada and Gandhaka underwent Shodhana to remove impurities [see source text or glossary: Shodhana].
10) Kajjali:
Kajjali is a crucial preparation in Rasashastra, made by triturating mercury and sulfur until a jet-black, smooth, and lustreless powder is obtained. It is the base for making other formulations like Parpati [see source text or glossary: Kajjali].
11) Paka:
Paka refers to the process of heating or cooking the Pottali in specific conditions. In the study, Paka of Pottali was conducted using the Bhudharaputa method, involving high temperatures over extended periods [see source text or glossary: Paka].
12) Patra:
Patra means leaf in Sanskrit. In the preparation of Rasa pottali, Tamboola patra and Dhatura patra were used for Bhavana (levigation) and Lepana (coating) to enhance the formulation’s properties [see source text or glossary: Patra].
13) Drug:
[see source text or glossary: Drug]
14) Rasaparpati (Rasa-parpati):
[see source text or glossary: Rasaparpati]
15) Sudha:
Sudha refers to lime, a key ingredient in the Shodhana (purification) process of Parada (mercury). It helps in the oxidation and removal of impurities from mercury [see source text or glossary: Sudha].
16) Rasashastra (Rasa-shastra, Rasasastra):
Rasashastra is a branch of Ayurveda focusing on the preparation, purification, and use of minerals and metals in medicine. It involves complex procedures to ensure the safety and efficacy of these formulations [see source text or glossary: Rasashastra].
17) Sudhakara (Sudha-akara, Sudha-kara):
[see source text or glossary: Sudhakara]
18) Prakasha (Prakasa):
[see source text or glossary: Prakasha]
19) Mineral:
Minerals are crucial in Rasashastra, where they undergo Shodhana (purification) and Bhasma (calcination) processes. These steps make minerals therapeutically usable in Ayurvedic formulations [see source text or glossary: Mineral].
20) Rasaprakashasudhakara (Rasaprakasasudhakara, Rasaprakasa-sudhakara):
Rasaprakasha Sudhakara is a classical Rasashastra text by Acharya Yashodhara, which provides unique formulations and methods, such as that for Rasa pottali [see source text or glossary: Rasaprakasha-sudhakara].
21) Mardana:
Mardana is the process of grinding or triturating, used extensively in Rasashastra to prepare substances like Kajjali. It helps in achieving the desired consistency and incorporating active principles [see source text or glossary: Mardana].
22) Lashuna (Lasuna):
Lashuna, or garlic, is used in the Shodhana (purification) of Parada (mercury) due to its detoxifying properties. It contains sulfur compounds which bind with toxic elements, aiding in their removal [see source text or glossary: Lashuna].
23) Dravya:
In Ayurveda, Dravya refers to substances or materials used to prepare medicines. It encompasses herbs, minerals, and metals, which are processed through various methods like Shodhana and Bhavana [see source text or glossary: Dravya].
24) Lepana:
Lepana is the process of applying herbal paste as a coating. In the study, Dhatura patra kalka was used for Lepana over Pottali, ensuring the active ingredients are well-integrated [see source text or glossary: Lepana].
25) Powder:
[see source text or glossary: Powder]
26) Shri (Sri, Sr):
[see source text or glossary: Shree]
27) Kalpana:
[see source text or glossary: Kalpana]
28) Cotton:
Cotton was used in several steps, such as filtering purified Parada and sealing apparatus during Gandhaka Shodhana, preventing contamination and maintaining purity [see source text or glossary: Cotton].
29) Puta:
Puta is a traditional Ayurvedic method of heating used in the preparation of medicines. The Bhudharaputa method involves heating Pottali over a specific temperature range and duration to induce chemical changes [see source text or glossary: Puta].
30) Milk:
Milk, or Godugdha, was used in the Shodhana (purification) process of Gandhaka (sulfur), balancing its Pitta-enhancing properties and adding Jeevaniya (life-giving) qualities to the formulation [see source text or glossary: Milk].
31) Saindhava (Saimdhava):
Saindhava, or rock salt, is used in the Shodhana process of Parada to help reduce toxicity and improve its assimilation. Its Teekshna (sharp) and Vishada (clear) properties aid in detoxification [see source text or glossary: Saindhava].
32) Ghi (Ghee):
Ghee, or clarified butter, is used in Rasashastra for the Shodhana (purification) of substances like Gandhaka. Its Madhura (sweet), Snigdha (unctuous), and Vata-pitta-shamak properties aid in detoxification [see source text or glossary: Ghee].
33) Khalvayantra (Khalva-yantra):
Khalva-yantra is a traditional Ayurvedic grinding apparatus used in processes like Bhavana and Mardana to triturate ingredients into fine powders or pastes uniformly [see source text or glossary: Khalva-yantra].
34) Putapaka (Puta-paka):
Puta-paka refers to the heating process in Ayurveda specifically applied to Pottali to induce chemical changes and ensure homogeneity, involving temperatures ranging from 322°C to 520°C [see source text or glossary: Puta-paka].
35) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine that emphasizes the use of natural substances, including metals and minerals in Rasashastra, for therapeutic purposes [see source text or glossary: Ayurveda].
36) Rasayana (Rasa-ayana):
Rasayana therapies in Ayurveda aim to rejuvenate and promote longevity. Rasa pottali can act as Rasayana due to its composition and preparation methods [see source text or glossary: Rasayana].
37) Samanya:
[see source text or glossary: Samanya]
38) Yantra (Yamtra):
Yantra refers to apparatus or instruments used in Ayurvedic medicine preparation. Examples include Khalva-yantra for grinding and Puta for heating [see source text or glossary: Yantra].
39) Pitta:
Pitta is one of the three doshas in Ayurveda representing heat and metabolism. Shodhana processes often aim to neutralize Pitta-enhancing effects of substances like Gandhaka [see source text or glossary: Pitta].
40) Cow dung:
Cow dung cakes were used as a fuel in the Paka process for heating Rasa pottali, maintaining a sustained and controlled temperature environment [see source text or glossary: Cow dung].
41) Saindhavalavana (Saindhava-lavana, Saimdhavalavana):
Saindhava-lavana is rock salt used in Shodhana (purification) of Parada, aiding in detoxification with its Teekshna and Vishada properties [see source text or glossary: Saindhava-lavana].
42) Purification:
Purification is the process of detoxifying metals and minerals in Rasashastra to make them safe for medicinal use, as seen with Parada and Gandhaka [see source text or glossary: Purification].
43) Rasaushadhi (Rasa-aushadhi, Rasausadhi):
Rasaushadhi refers to mercurial or herbo-mineral medicines in Ayurveda, known for their potent therapeutic effects [see source text or glossary: Rasaushadhi].
44) Bhaishajya (Bhaisajya):
Bhaishajya means medicine or therapeutics in Ayurveda. It involves the preparation and use of various formulations for treating ailments [see source text or glossary: Bhaishajya].
45) Medicine:
Traditional Ayurvedic medicine involves complex processes like Shodhana and Bhavana to create formulations that incorporate metals, minerals, and herbs [see source text or glossary: Medicine].
46) Shuddha (Suddha):
Shuddha means purified. In the context of Rasashastra, Shuddha Parada (purified mercury) and Shuddha Gandhaka (purified sulfur) are essential for safe and effective formulations [see source text or glossary: Shuddha].
47) Ghrita (Ghrta):
Ghrita is clarified butter used in the Shodhana (purification) of substances like Gandhaka to neutralize their heating effects and impart nourishing properties [see source text or glossary: Ghrita].
48) Jaipur:
[see source text or glossary: Jaipur]
49) Lavana:
Lavana means salt. In Rasashastra, Saindhava lavana (rock salt) is utilized in the Shodhana process of Parada to aid in detoxification [see source text or glossary: Lavana].
50) Nature:
[see source text or glossary: Nature]
51) India:
India is the country where Ayurveda, including Rasashastra, originated and continues to be practiced extensively for its holistic health benefits [see source text or glossary: India].
52) Glass:
Glass containers are used to store purified substances like Rasa pottali post-preparation to maintain their integrity and prevent contamination [see source text or glossary: Glass].
53) Fire:
Fire is used in the Paka process, where controlled heating is essential for the preparation and finalization of formulations like Rasa pottali [see source text or glossary: Fire].
54) Shuddhagandhaka (Suddhagandhaka, Shuddha-gandhaka):
[see source text or glossary: Shuddha-gandhaka]
55) Shuddhaparada (Suddhaparada, Shuddha-parada):
[see source text or glossary: Shuddha-parada]
56) Transformation (Transform, Transforming):
[see source text or glossary: Transformation]
57) Madhurarasa (Madhura-rasa):
[see source text or glossary: Madhura-rasa]
58) Yashodhara (Yasodhara, Yashas-dhara):
Acharya Yashodhara is the author of Rasaprakasha Sudhakara, a seminal text in Rasashastra detailing sophisticated preparations like Rasa pottali [see source text or glossary: Yashodhara].
59) Discussion:
[see source text or glossary: Discussion]
60) Rajasthan:
[see source text or glossary: Rajasthan]
61) Samskara:
[see source text or glossary: Samskara]
62) Rasayoga (Rasa-yoga):
[see source text or glossary: Rasayoga]
63) Bhudhara (Bhu-dhara):
Bhudhara refers to the pit method used for the Paka process in preparing Rasa pottali, involving bio-thermal heating with cow dung cakes [see source text or glossary: Bhudhara].
64) Goghrita (Goghrta, Go-ghrita):
[see source text or glossary: Goghrita]
65) Godugdha:
[see source text or glossary: Godugdha]
66) Toxicity:
[see source text or glossary: Toxicity]
67) Madhura:
[see source text or glossary: Madhura]
68) Visada (Vishada, Visha-da):
[see source text or glossary: Vishada]
69) Laghuta:
[see source text or glossary: Laghuta]
70) Bhasma (Bhasman):
Bhasma refers to the ash obtained by calcining metals or minerals in traditional Ayurvedic medicine, used for its therapeutic properties after thorough Shodhana [see source text or glossary: Bhasma].
71) Bandha (Bamdha):
[see source text or glossary: Bandha]
72) Mishra (Misra):
[see source text or glossary: Mishra]
73) Ratna:
[see source text or glossary: Ratna]
74) Ushna (Usna):
[see source text or glossary: Ushna]
75) Ayus (Ayush):
AYUSH is an acronym for Ayurveda, Yoga, Unani, Siddha, and Homeopathy, representing India's traditional systems of medicine [see source text or glossary: Ayush].
[Note: The above list is limited to 75. Total glossary definitions available: 80]
Other Science Concepts:
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Rasashastra, Rasaushadhi, Rasaprakashasudhakara, Therapeutic application, Herbo-mineral formulation, Gandhaka Shodhana, Standard Operative Procedure, Kajjali Preparation, Parada Shodhana, Clinical use, Paka method, Pottali Kalpana, Manufacturing process, Murchita parada yoga, Quality profiles, Bhavana-proces.