Efficacy study of triphala kwath vs. trikatu for dyslipidemia.
Journal name: Ayushdhara
Original article title: A comparative clinical efficacy study of triphala kwath and trikatu capsules in the management of medoroga w.s.r to dyslipidemia
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Anjli Sharma
MD Scholar, Dept of Kayachikitsa, RGGPG Ayurvedic College, Paprola, Himachal Pradesh, India.
Anjana Mishra
Reader, Dept of Kayachikitsa, RGGPG Ayurvedic College, Paprola, Himachal Pradesh, India.
Manik Soni
Lecturer, Dept of Kayachikitsa, RGGPG Ayurvedic College, Paprola, Himachal Pradesh, India.
Vijay Chaudhary
Professor and HOD., Dept of Kayachikitsa, RGGPG Ayurvedic College, Paprola, Himachal Pradesh, India.
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: A comparative clinical efficacy study of triphala kwath and trikatu capsules in the management of medoroga w.s.r to dyslipidemia
Year: 2020 | Doi: 10.47070/ayushdhara.v7i5.624
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Introduction
The study presented in this article investigates the clinical efficacy of two Ayurvedic formulations, Triphala Kwath and Trikatu capsules, in the management of Dyslipidemia, referred to as Medoroga in Ayurveda. Medoroga is characterized by an excessive accumulation of fat tissues in the body, leading to various health issues such as cardiovascular diseases. The study evaluates the effects of these herbal interventions over an 8-week period on various clinical parameters related to lipid profiles. A total of 20 patients, aged 40-60, participated in the trial, divided into two groups, with one receiving Trikatu capsules and the other receiving a combination of Triphala Kwath with Madhu and Trikatu capsules.
Triphala Kwath's Efficacy in Lipid Management
One of the crucial findings of the study highlights the significant improvement in lipid profiles in the group receiving Triphala Kwath with Madhu. This formulation demonstrated a remarkable reduction in serum cholesterol, triglycerides, LDL, and VLDL levels while showing an increase in HDL levels. The statistical analysis indicated a significant improvement (p < 0.001) in lipid parameters, affirming that Triphala Kwath effectively addresses the excessive fat accumulation in Ayurvedic terms, thereby alleviating the conditions associated with Medoroga. The ingredients of Triphala, known for their tridoshic (balancing all three doshas) properties, contribute to overall health enhancement and management of dyslipidemia.
Trikatu's Role in Enhancing Digestion and Metabolism
In addition to the lipid-lowering effects of Triphala Kwath, the study underlines the importance of Trikatu capsules, known for their digestive and metabolic benefits. Trikatu, composed of ginger, black pepper, and long pepper, enhances digestive health by increasing the secretion of digestive juices. This action aids in the efficient metabolism of absorbed lipids, thereby preventing their excessive accumulation in the body. The results indicated that patients receiving Trikatu capsules exhibited improved metabolic functions, further substantiating its role in managing dyslipidemia. The combination of both formulations proved to be particularly effective, addressing both the symptomatic and underlying causes of Medoroga.
Conclusion
The findings from this study suggest that the combination of Triphala Kwath with Madhu and Trikatu capsules can be considered an effective Ayurvedic treatment for managing dyslipidemia (Medoroga). The significant improvements in lipid profiles and associated symptoms demonstrate the therapeutic potential of these herbal interventions without any adverse effects. The study thus supports the integration of traditional Ayurvedic practices into contemporary health management strategies, particularly for tackling lifestyle-related diseases such as dyslipidemia in a holistic manner. Further research may explore the long-term effects of these formulations and their potential in broader applications within Ayurvedic medicine.
FAQ section (important questions/answers):
What is Medoroga and how is it related to dyslipidemia?
Medoroga is characterized by excessive accumulation of Meda Dhatu, leading to poor nourishment of other Dhathus. In modern terms, it correlates with dyslipidemia, marked by abnormal lipid levels, including elevated cholesterol and triglycerides, which poses significant health risks.
What treatments were compared in the study for dyslipidemia?
The study compared the efficacy of Triphala Kwath with Madhu and Trikatu capsules against Trikatu capsules alone. Twenty patients were divided into two groups to evaluate their effectiveness in managing dyslipidemia over an eight-week period.
What were the results of the treatments in the study?
Results indicated that Group II, receiving Triphala Kwath with Madhu and Trikatu, showed significant improvements in lipid profiles, reducing cholesterol and triglycerides while increasing HDL levels, without adverse effects, outperforming Group I which received only Trikatu capsules.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Efficacy study of triphala kwath vs. trikatu for dyslipidemia.�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Trikatu (Tri-katu):
Trikatu comprises three key ingredients: Sonth, Marich, and Pippali. It has Katu Rasa and Katu Vipaka, Ushna Virya, and Laghu Ruksha Guna qualities, making it effective for reducing Medodhatu (body fat) and making channels in the body more patent by acting as a digestive and metabolic enhancer.
2) Triphala (Tri-phala):
Triphala, consisting of Haritaki, Bibhitaka, and Amalaki, is known for its Laghu, Ruksha Guna, and Ushna Virya. It is used in Ayurvedic medicine for its Tridoshhara properties, capable of balancing Vata, Pitta, and Kapha doshas, making it effective against Medoroga (dyslipidemia).
3) Medoroga (Medas-roga):
Medoroga, in Ayurveda, refers to the excessive accumulation of Meda Dhatu in the body, causing blockages in Strotsa and leading to conditions like dyslipidemia, characterized by elevated levels of cholesterol, triglycerides, and LDL, and reduced HDL in the blood.
4) Madhu:
Madhu (honey) is used as an Anupana in combination therapies due to its Kashaya Rasa, Guru, and Ruksha Guna. In the context of this study, it potentiates the effects of Triphala Kwath and Trikatu Capsules, aiding in the management of Medoroga by enhancing the drugs' therapeutic properties.
5) Drug:
In the study, the drugs used are Triphala Kwath and Trikatu Capsules. These are traditional formulations, each having specific pharmacological properties, aimed at treating Medoroga (dyslipidemia) by improving lipid profiles and enhancing overall metabolic functions without adverse effects.
6) Dhatu:
In Ayurveda, Dhatus are fundamental bodily tissues, such as Meda Dhatu, Vasa, and Majja Dhatu, each associated with specific properties and functions. An imbalance in these dhatus, particularly Meda Dhatu, is closely linked to conditions such as Medoroga (dyslipidemia).
7) Disease:
The primary disease focus in this study is Medoroga, correlated with dyslipidemia in modern medical terms. It implies the excessive buildup of Meda Dhatu (fat tissue), leading to altered lipid profiles, which are risk factors for cardiovascular diseases.
8) Sharman (Sarma, Sharma, Sarman):
Dr. Anjli Sharma, an MD Scholar, is a primary researcher in this study. Along with her colleagues, she designed and conducted the comparative clinical efficacy study of Triphala Kwath and Trikatu Capsules in managing Medoroga (dyslipidemia).
9) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine that aims to balance bodily doshas and dhatus. It uses natural formulations, like Triphala and Trikatu, for treating conditions like Medoroga (dyslipidemia) by leveraging the properties of medicinal herbs.
10) Dosha (Dosa):
Doshas, namely Vata, Pitta, and Kapha, are fundamental bio-elements in Ayurveda, governing physiological and psychological functions. Imbalance in these doshas, especially Kapha in conjunction with Meda Dhatu, plays a crucial role in diseases like Medoroga.
11) Kapha:
Kapha is one of the three doshas in Ayurveda, representing structural and lubrication elements in the body. An excessive Kapha, particularly in combination with Meda Dhatu, leads to the development of Medoroga, causing issues such as dyslipidemia.
12) Laghu:
Laghu (light) is a quality attributed to certain Ayurveda formulations like Triphala and Trikatu. This characteristic aids in reducing body fat and improving metabolism, making it beneficial in the treatment of Medoroga (dyslipidemia).
13) Blood:
Blood tests, including serum cholesterol, triglycerides, LDL, VLDL, and HDL, are used to assess the effectiveness of treatments for Medoroga (dyslipidemia). These lipid profile measurements determine the impact of Triphala Kwath and Trikatu Capsules on patients.
14) Rasa (Rasha):
Rasa (taste) is a fundamental concept in Ayurveda influencing the therapeutic effect of herbs. Trikatu possesses Katu Rasa, which aids digestion and metabolism, playing a key role in managing Medoroga (dyslipidemia) by lowering lipid levels.
15) Yoga:
[see source text or glossary: Yoga]
16) Medas (Meda, Medash):
Meda Dhatu, associated with body fat, is deeply involved in Medoroga (dyslipidemia). Excess Meda leads to blockages in the Strotsa, impairing nourishment of other Dhatus, and necessitating treatments like Triphala and Trikatu to restore balance.
17) Guna:
Guna, or quality, defines the attributes of substances in Ayurveda. Triphala and Trikatu exhibit Gunas like Laghu (light) and Ruksha (dry), which contribute to their effectiveness in reducing Meda Dhatu and treating Medoroga (dyslipidemia).
18) Pain:
[see source text or glossary: Pain]
19) Nidradhikya (Nidra-adhikya):
Nidradhikya, or excessive sleep, is a symptom associated with Medoroga (dyslipidemia) addressed in the study. Improvements in this symptom were observed, especially in patients treated with Triphala Kwath and Trikatu Capsules.
20) Daurgandhya:
Daurgandhya refers to bad body odor, a symptom linked with Medoroga (dyslipidemia). The study observed significant improvement in this parameter, particularly in patients administered the combination of Triphala Kwath and Trikatu Capsules.
21) Atimatra:
[see source text or glossary: Atimatra]
22) Medicine:
Medicine in this study refers to the Ayurvedic formulations Triphala Kwath and Trikatu Capsules. These were evaluated for their efficacy in managing Medoroga (dyslipidemia), focusing on their impact on lipid profiles and overall patient health.
23) Kshudha (Ksudha):
[see source text or glossary: Kshudha]
24) Kshudra (Ksudra):
[see source text or glossary: Kshudra]
25) Sandhi (Shandhi, Samdhi):
Sandhi Shoola, or joint pain, is a symptom assessed in the study of Medoroga (dyslipidemia). Significant improvements were observed in this symptom among patients treated with Triphala Kwath and Trikatu Capsules, highlighting their therapeutic benefits.
26) Pipasa:
[see source text or glossary: Pipasa]
27) Nature:
[see source text or glossary: Nature]
28) India:
India is the origin of Ayurveda, the traditional system of medicine used in the study. The research was conducted in an Ayurvedic college and hospital in Himachal Pradesh, showcasing India's ongoing contributions to integrative medicine.
29) Food:
Food habits such as excessive consumption of unhealthy diets contribute to Medoroga (dyslipidemia). The study includes dietary considerations and uses formulations like Triphala and Trikatu to manage imbalances caused by poor dietary choices.
30) Diet:
Diet plays a significant role in the development and management of Medoroga (dyslipidemia). The study suggests that inappropriate diet is one of the etiological factors for Medoroga, and that treatments like Triphala and Trikatu can help mitigate the effects.
31) Pharmacological:
Pharmacological characteristics of Triphala and Trikatu, like Deepana (appetizer) and Pachana (digestive), are crucial for treating Medoroga (dyslipidemia). Their actions on lipid metabolism and overall health were evaluated in the study.
32) Jatharagni (Jathara-agni):
Jatharagni (digestive fire) is fundamental in Ayurveda for digestion and metabolism. An improved Jatharagni, through formulations like Trikatu, aids in better lipid metabolism and management of Medoroga (dyslipidemia).
33) Medadhatu (Meda-dhatu):
Meda Dhatu is the fat tissue in the human body, whose imbalance leads to Medoroga (dyslipidemia). Managing this Dhatu through Ayurvedic treatments like Triphala and Trikatu helps in restoring metabolic balance and reducing excess fat.
34) Koshtha (Kostha):
Kostha refers to the digestive tract in Ayurveda. Classification of patients based on Kostha (Mridu, Madhyam, Krura) helps tailor treatments for Medoroga (dyslipidemia), ensuring efficacy based on individual digestive tendencies.
35) Anupana:
Anupana is a vehicle or substance taken along with medicine to enhance its therapeutic effects. In the study, Madhu (honey) is used as an Anupana with Triphala Kwath and Trikatu to potentiate the drugs' efficacy in treating Medoroga (dyslipidemia).
36) Ruksha (Ruksa):
Ruksha (dry) is a Guna (quality) of substances in Ayurveda. Both Triphala and Trikatu exhibit Ruksha qualities, which help in reducing Meda Dhatu and managing conditions like Medoroga (dyslipidemia) by decreasing fat accumulation.
37) Vipaka:
Vipaka refers to the post-digestive effect of a substance. Trikatu has Katu Vipaka, which means its effects after digestion are pungent, aiding in reducing Meda Dhatu and improving metabolic functions in the management of Medoroga (dyslipidemia).
38) Kangra:
Kangra is the district in Himachal Pradesh, India, where the Rajiv Gandhi Govt Post Graduate Ayurvedic College and Hospital are located. The study on Triphala and Trikatu for treating Medoroga (dyslipidemia) was conducted at this institution.
39) Chala (Chala°):
[see source text or glossary: Chala]
40) Udara:
[see source text or glossary: Udara]
41) Stana:
[see source text or glossary: Stana]
42) Katu:
Katu (pungent) is one of the six tastes in Ayurveda, contributing to digestion and metabolism. Trikatu, with its Katu Rasa, is used in the study for its role in reducing Meda Dhatu and treating Medoroga (dyslipidemia).
43) Vata:
Vata is a dosha that governs movement and physiological processes. Imbalances in Vata, alongside Kapha and Medodhatu, contribute to conditions like Medoroga (dyslipidemia). Treatments like Trikatu help balance these doshas and alleviate symptoms.
44) Science (Scientific):
[see source text or glossary: Scientific]
45) Pradhana:
[see source text or glossary: Pradhana]
46) Rasayana (Rasa-ayana):
Rasayana (rejuvenation) therapies aim to improve health and longevity. In the context of this study, Triphala acts as a Rasayana, enhancing digestive health and lipid metabolism, thereby aiding in the management of Medoroga (dyslipidemia).
47) Prakriti (Prakrti):
Prakriti, or constitution, determines an individual’s physical and psychological traits. In the study, patients' Prakriti is considered, with Vatakaphaj Prakriti being predominant, affecting the treatment outcomes for Medoroga (dyslipidemia).
48) Atiyoga:
[see source text or glossary: Atiyoga]
49) Alavana:
[see source text or glossary: Alavana]
50) Kashaya (Kasaya):
Kashaya (astringent) is a taste in Ayurveda with properties of drying and tightening tissues. Madhu (honey), used as an Anupana in the study, has Kashaya Rasa, aiding in the treatment of Medoroga (dyslipidemia) by reducing fat and enhancing drug efficacy.
51) Family:
[see source text or glossary: Family]
52) Karma (Karman):
[see source text or glossary: Karma]
53) Ushna (Usna):
Ushna (hot) refers to the potency of a substance in Ayurveda. Both Triphala and Trikatu have Ushna Virya, which aids in the digestion and reduction of Meda Dhatu, making them effective in treating Medoroga (dyslipidemia).
54) Virya:
[see source text or glossary: Virya]
55) Sugar:
[see source text or glossary: Sugar]
56) Death:
[see source text or glossary: Death]
57) Agni:
Agni, or digestive fire, is vital in Ayurveda for metabolism and health. Enhancing Agni through formulations like Trikatu is crucial for treating Medoroga (dyslipidemia), as it improves digestion and reduces fat accumulation.
58) Human body:
[see source text or glossary: Human body]
59) Krurakoshtha (Krurakostha, Krura-koshtha):
Krura Koshtha categorizes patients with slow and difficult bowel movements. This classification is important in the study to tailor treatments for Medoroga (dyslipidemia), ensuring effective management based on individual digestive tendencies.
60) Mridukoshtha (Mrdukostha, Mridu-koshtha):
Mridu Koshtha is a category describing patients with soft and regular bowel movements. This categorization helps in understanding individual responses to treatments like Triphala and Trikatu in managing Medoroga (dyslipidemia).
61) Majjadhatu (Majja-dhatu):
[see source text or glossary: Majja-dhatu]
62) Kaphadosha (Kaphadosa, Kapha-dosha):
Kapha Dosha is one of the three primary bio-elements in Ayurveda, responsible for structure and lubrication. Its imbalance, particularly with Meda Dhatu, leads to conditions like Medoroga (dyslipidemia), which the study aims to treat using Triphala and Trikatu.
63) Agnimandya (Agni-mandya, Agnimamdya):
Agnimandya, or digestive weakness, is a condition where the body's digestive fire (Agni) is impaired. Ayurvedic treatments like Trikatu and Triphala target Agnimandya to improve lipid metabolism and manage Medoroga (dyslipidemia).
64) Discussion:
The discussion section of the study elaborates on the findings and efficacy of Triphala and Trikatu in treating Medoroga (dyslipidemia). It interprets data from objective and subjective assessments, supporting the therapeutic benefits observed.
65) Knowledge:
[see source text or glossary: Knowledge]
66) Substance:
[see source text or glossary: Substance]
67) Katurasa (Katu-rasa):
Katu Rasa means pungent taste in Ayurveda. It is attributed to Trikatu, which helps stimulate digestion and metabolism. This quality makes it effective in managing conditions like Medoroga (dyslipidemia) by reducing Meda Dhatu (body fat).
68) Haritaki:
Haritaki is one of the key ingredients in Triphala. It has Laghu and Ruksha Gunas with Ushna Virya, making it effective in reducing Meda Dhatu and improving digestive health. In the study, it contributes to treating Medoroga (dyslipidemia).
69) Rukshana (Ruksana):
Rukshana refers to the drying property in Ayurveda. Ingredients with Ruksha Guna, such as those in Trikatu, are useful in treating Medoroga (dyslipidemia) by reducing excess Meda Dhatu (fat tissue) and improving metabolic functions.
70) Shoshana (Sosana):
[see source text or glossary: Shoshana]
71) Bhutagni (Bhuta-agni):
[see source text or glossary: Bhutagni]
72) Sweating (Sweat):
[see source text or glossary: Sweating]
73) Samhita:
[see source text or glossary: Samhita]
74) Lekhana:
Lekhana refers to scraping or reducing excess tissue in Ayurveda. Trikatu possesses Lekhana properties, making it effective in reducing Meda Dhatu (body fat) and treating Medoroga (dyslipidemia) by facilitating the removal of excess lipids.
75) Sukshma (Suksma, Shukshma):
Sukshma refers to subtlety or fineness. Trikatu is described as having Sukshma qualities, allowing it to penetrate tissues effectively. This property aids in reducing Meda Dhatu and treating Medoroga (dyslipidemia) by improving metabolic processes.
[Note: The above list is limited to 75. Total glossary definitions available: 102]
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