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A comparative study on chronic administration of Go Ghrita (cow ghee) and Avika Ghrita (ewe ghee) in albino rats

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Journal name: AYU (Journal of Research in Ayurveda)
Original article title: A comparative study on chronic administration of Go Ghrita (cow ghee) and Avika Ghrita (ewe ghee) in albino rats
AYU is an internationally recognized quarterly journal dedicated to advancing research in Ayurveda. The journal covers a wide range of topics, including clinical and pharmacological research in Ayurveda's eight branches, herbal remedies, phytochemistry, and ethnomedicine.

Original source:

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Author(s):

Dipali J. Shukla
Hitesh A. Vyas
Mahesh Kumar Vyas
B. K. Ashok
B. Ravishankar


AYU (Journal of Research in Ayurveda):

(An International Quarterly Journal of Research in Ayurveda)

Full text available for: A comparative study on chronic administration of Go Ghrita (cow ghee) and Avika Ghrita (ewe ghee) in albino rats

Year: 2012 | Doi: 10.4103/0974-8520.108862

Copyright (license): CC BY-NC-SA 4.0


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Summary of article contents:

Ghrita (ghee) is the foremost substance of Indian cuisine from centuries. Ayurvedic classics described eight kinds of ghee from eight different animal milk, among them ghee made from cow milk is said to be the superior and ghee of ewe milk is said to be the inferior and also detrimental to heart. The present study was undertaken to evaluate chronic administration of cow ghee (Go Ghrita) and ghee of ewe milk (Avika Ghrita) to experimental animals. Experiment was carried out on Wistar strain albino rats and study was done at two dose levels. The test drugs were administered orally for 45 consecutive days. Parameters, such as gross behavior, body weight, weight of important organs, total fecal fat content, electrocardiogram, serum biochemical parameters, and histopathology of different organs were studied. Both the test drugs did not alter the gross behavior, body weight, weight of organs, and cytoarchitecture of different organs to significant extent. Avika Ghrita at a low dose significantly decreased triglyceride content, significantly prolonged QTc and at both dose levels it significantly shortened the PR interval. This study shows chronic administration of Avika Ghrita and Go Ghrita has no marked differences between them except the QTc prolongation in Avika Ghrita. This may be the basis for the classics to categorize Avika Ghrita as Ahridya. Keywords: Ahridya, albino rats, Avika Ghrita, cholesterol, ghee, Go Ghrita

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Discover the significance of concepts within the article: �A comparative study on chronic administration of Go Ghrita (cow ghee) and Avika Ghrita (ewe ghee) in albino rats�. Further sources in the context of Science might help you critically compare this page with similair documents:

Ahridya, Goghrita, Maximum Dose, Wistar strain albino rats, Body weight, Chronic administration, Electrocardiogram, Serum biochemical parameters, Biochemical parameter.

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