Phytochemical screening and antimicrobial study of Artocarpus lakoocha.
Journal name: Ancient Science of Life
Original article title: Preliminary Phytochemical screening and antimicrobial studies on Artocarpus lakoocha Roxb
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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Anima Pandey, S.P. Bhatnagar
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Preliminary Phytochemical screening and antimicrobial studies on Artocarpus lakoocha Roxb
Year: 2009
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
Artocarpus lakoocha Roxb, commonly recognized for its medicinal properties, has been utilized by the tribal communities of Jharkhand, India, for treating various diseases, particularly in wound healing. Despite its traditional use, there is limited scientific exploration into its antimicrobial potential, specifically concerning the bark of this species. This study aims to investigate the antimicrobial efficacy of A. lakoocha bark against several bacterial strains, with a focus on developing a new antimicrobial formulation that could be beneficial for therapeutic applications.
Antimicrobial Activity of A. lakoocha Bark
The study involved the extraction of the bark using solvents like petroleum ether, chloroform, and methanol, followed by thorough phytochemical screening. Results indicated the presence of various phytoconstituents, including flavonoids, tannins, triterpenoids, and glycosides. The minimum inhibitory concentration (MIC) tests demonstrated that the methanolic extract of A. lakoocha had significant antibacterial activity against several gram-negative bacteria, including E. coli and Shigella species at concentrations as low as 200-400 µg/ml. Notably, the extracts efficiently inhibited the growth of specific bacterial strains, underscoring their potential value as natural antimicrobial agents.
Conclusion
The findings of this study suggest that A. lakoocha bark exhibits considerable antimicrobial properties, which may serve as a foundation for developing new therapeutic options. Its rich phytochemical composition could potentially contribute to enhanced wound healing and infection control strategies. Overall, this research not only highlights the medicinal significance of A. lakoocha but also emphasizes the need for further studies to isolate active compounds and understand their mechanisms, paving the way for innovative applications in modern medicine.
FAQ section (important questions/answers):
What traditional uses does Artocarpus lakoocha have in Jharkhand?
The tribal people of Jharkhand use Artocarpus lakoocha for various medicinal purposes, particularly for wound healing. Its bark is applied to sores, and it is known for its effectiveness against stomach and liver diseases.
What extraction methods were used for Artocarpus lakoocha bark?
The bark of Artocarpus lakoocha was successively extracted using petroleum ether, chloroform, and methanol. The extracts were then dried and concentrated under reduced pressure for further analyses.
Which microorganisms were tested against Artocarpus lakoocha bark extracts?
Thirteen species of bacteria were tested, including S. aureus, E. coli, and Shigella species. The methanolic extract showed significant antibacterial activity against several gram-negative bacteria.
What were the findings regarding the antibacterial activity of A. lakoocha?
The study found that the methanolic extract of A. lakoocha exhibited good antibacterial activity, particularly at concentrations of 200 µg/ml and 400 µg/ml, effectively inhibiting growth of specific bacteria.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Phytochemical screening and antimicrobial study of Artocarpus lakoocha.�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Activity:
In the context of the study, 'Activity' refers to the ability of the methanolic extract of Artocarpus lakoocha bark to inhibit the growth of various bacteria. The assessment of antimicrobial activity is crucial for determining the potential therapeutic applications of plant extracts in treating infections caused by these bacteria.
2) Phytochemical:
The term 'Phytochemical' relates to the chemical compounds that are produced by plants, which may have biological significance. In this study, phytochemicals like flavonoids and tannins were identified in Artocarpus lakoocha, contributing to its medicinal properties and potential efficacy in wound healing and antimicrobial activity.
3) Antibiotic (Antibacterial):
The word 'Antibacterial' describes a substance's ability to kill or inhibit the growth of bacteria. This study investigates the antibacterial properties of Artocarpus lakoocha, focusing on its effectiveness against various bacterial strains, which is vital for developing new antimicrobial therapies derived from natural sources.
4) Flavonoid:
Flavonoids are a class of phytochemicals with known health benefits, including antioxidant and antimicrobial properties. The study's identification of flavonoids in Artocarpus lakoocha suggests that these compounds may play a significant role in the plant’s medicinal effects and contribute to its antibacterial activity.
5) Science (Scientific):
The term 'Scientific' pertains to the rigorous methodology employed in the study. It emphasizes the use of systematic procedures to explore the antimicrobial properties of Artocarpus lakoocha, reinforcing the importance of adhering to scientific principles in validating traditional medicinal uses.
6) Drug:
In the context of this study, 'Drug' refers to substances used to treat diseases or conditions. The methanolic extract of Artocarpus lakoocha is explored for its potential to develop a natural drug that could be effective against bacterial infections, contributing to the field of pharmacognosy.
7) Discussion:
'Discussion' in the study presents an analysis of the results obtained from the phytochemical screenings and antibacterial tests. This section evaluates the implications of the findings, relates them to existing literature, and highlights the significance of Artocarpus lakoocha in contemporary medicinal practices.
8) Shukla (Sukla):
'Shukla' likely refers to a contributor, possibly a co-researcher or author of the study. In academic and scientific texts, mentioning contributors is vital for attributing the research and providing credibility to the findings, as it indicates collaboration and shared expertise.
9) Cita:
'Sida' is a genus of flowering plants known for their medicinal properties. Its mention in the study highlights the traditional herbal practices of the local tribes in Jharkhand, indicating that various plants, including Sida and Artocarpus, have been utilized for wound healing and other therapeutic purposes.
Other Science Concepts:
Discover the significance of concepts within the article: �Phytochemical screening and antimicrobial study of Artocarpus lakoocha.�. Further sources in the context of Science might help you critically compare this page with similair documents:
Scientific literature, Medicinal use, Sore treatment, Antibacterial activity, Preliminary phytochemical screening, Minimum inhibitory concentration, Wound healing properties, Folklore medicine, Phytochemical studies, Standard drug, Gram negative bacteria, Plant material extraction, Antimicrobial studies, Ciprofloxacin, Bacterial culture, Polyphenolic compound, Extracted plant material, Shade tree.