鈥渆ffect of swarna vanga on madhumeha in albino rats鈥�
Journal name: Ancient Science of Life
Original article title: 鈥渆ffect of swarna vanga on madhumeha in albino rats鈥�
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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P. Suresh, Damodar Joshi, K. D. Gode, B. K. Chakravarty
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: 鈥渆ffect of swarna vanga on madhumeha in albino rats鈥�
Year: 1988
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
The study investigates the effects of Swarna Vanga on Madhumeha (diabetes) using albino rats. The authors explore the potential of mineralo-metallic preparations, particularly Swarna Vanga, a gold-like Ayurvedic formulation, recognized for its historical use in treating Pramehas from the 18th century. The researchers aim to assess the hypoglycaemic action of Swarna Vanga in both normoglycaemic and hyperglycaemic states, acknowledging its bitter taste, which is commonly considered beneficial for balancing vata and kapha doshas typifying Madhumeha.
Hypoglycaemic Effects of Swarna Vanga
The findings from the normoglycaemic study indicate that Swarna Vanga, particularly at the 1 gm/kg body weight dosage, yielded a significant reduction in blood sugar levels at the 1st, 3rd, and 6th-hour readings, while lower doses showed limited statistical significance in their hypoglycaemic effects. These results suggest that Swarna Vanga is more effective at higher doses in lowering blood sugar levels in normoglycaemic rats. Similarly, while the prophylactic study indicated a milder response in preventing hyperglycaemia following alloxan induction, treated groups experienced less drastic increases in blood sugar compared to control subjects. Despite these positive indications, the overall impact in these studies remains tentative.
Conclusion
In conclusion, the research demonstrates that Swarna Vanga exhibits notable hypoglycaemic effects in normoglycaemic rats, yet outcomes in prophylactic and alloxan-induced diabetic conditions do not achieve statistical significance. The results hint at a potential role for Swarna Vanga in managing blood sugar levels, but further investigation is warranted to establish its efficacy comprehensively, particularly in hyperglycaemic scenarios. The findings contribute to the understanding of traditional Ayurvedic treatments and their relevance in modern scientific research on diabetes management.
FAQ section (important questions/answers):
What is the purpose of studying Swarna Vanga in albino rats?
The study aims to assess the hypoglycaemic effects of Swarna Vanga, a mineral-metallic Ayurvedic preparation, on normoglycaemic and hyperglycaemic albino rats, particularly its curative and palliative properties in Madhumeha (diabetes).
What methodology was used for the experiments on albino rats?
Healthy adult albino rats were grouped and given Swarna Vanga in various dosages. Blood sugar levels were measured before and after drug administration, and diabetes was induced using alloxan in some experimental groups.
What were the results of Swarna Vanga on normal blood sugar levels?
Swarna Vanga showed a significant reduction in blood sugar levels in normoglycaemic rats, particularly at higher doses. The effect was less pronounced with lower doses and was statistically significant at 1 gm/kg.
What conclusions were drawn from the study's findings?
The study concluded that Swarna Vanga exhibits significant hypoglycaemic effects in normoglycaemic rats. However, its effect in prophylactic and alloxan-induced diabetic rats was not statistically significant, indicating a mild role in lowering blood sugar.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for 鈥溾�渆ffect of swarna vanga on madhumeha in albino rats鈥濃��. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Blood:
Blood is a vital fluid in the body that carries oxygen and nutrients to cells and removes waste products. In the context of the study, blood sugar levels are critical indicators of metabolic health, particularly in evaluating the efficacy of Swarna Vanga on diabetes in albino rats. Monitoring blood is essential for determining the hypoglycaemic action of the drug.
2) Sugar:
Sugar refers to glucose, a crucial energy source for the body, and its levels in the blood are significant in diagnosing and managing conditions like diabetes. The study aims to understand how Swarna Vanga affects blood sugar levels in both normal and diabetic animals, highlighting its potential therapeutic role.
3) Drug:
The term drug signifies any substance used for medical treatment or management of diseases. In this study, Swarna Vanga is investigated as a drug for its hypoglycaemic properties in treating Madhumeha, emphasizing the pursuit of effective herbal and mineralo-metallic remedies within Ayurvedic practices.
4) Prameha:
Prameha, a term in Ayurveda, refers to a group of metabolic disorders characterized by excessive urination and abnormalities in sugar metabolism. The study focuses on Madhumeha, a subtype of Prameha, aiming to evaluate the impact of Swarna Vanga in managing conditions associated with this disorder.
5) Vanga (V膩峁単a, Va峁単a, Va峁単膩, Vamga):
Vanga, or tin, is a key component in the preparation of Swarna Vanga, which is a mineralo-metallic remedy used in Ayurveda. Its relevance lies in its historical use in Ayurvedic therapeutics, particularly for metabolic disorders like Madhumeha, making it a focus of the study's investigation.
6) Kapha:
Kapha is one of the three doshas in Ayurveda, characterized by qualities of heaviness, wetness, and cold. The study investigates how Swarna Vanga interacts with doshas, particularly Kapha and Vata, in patients suffering from Madhumeha, an understanding rooted in traditional Ayurvedic physiology.
7) Water:
Water is essential for sustaining life and plays a crucial role in biological processes, including digestion and metabolism. In the context of the study, water consumption patterns in the rats were monitored, particularly during diabetes-induced conditions, to understand the impact of treatment on overall health and hydration.
8) Rasa (Ras膩, Rasha):
Rasa, in Ayurveda, means essence or taste and is also a term for medicinal preparations that utilize various substances, including metals and herbs. The study's focus on Rasa-Shastra, the science of alchemical medicines, demonstrates the historical context in which Swarna Vanga is utilized to treat metabolic disorders.
9) Diet:
Diet refers to the food consumed by the study subjects, which is crucial for determining their metabolic state. The experimental design included monitoring dietary habits of the normoglycaemic and diabetic rats, ensuring that conditions improved or worsened based on nutritional intake were properly assessed.
10) Science (Scientific):
Science represents the systematic study of the structure and behavior of the physical and natural world. In this context, the study employs scientific methods to investigate the pharmacological effects of Swarna Vanga, linking traditional Ayurvedic practices with modern experimental methodologies.
11) Bitter:
Bitter refers to a taste often associated with certain drugs or natural remedies in Ayurveda. Bitter substances are traditionally believed to help balance the doshas and treat conditions like Prameha, making the study relevant in evaluating how Swarna Vanga's taste and properties affect blood sugar levels.
12) Vata (V膩峁璦, Va峁璦, V膩ta, Va峁�):
Vata is another dosha in Ayurvedic medicine, characterized by qualities of dryness, lightness, and mobility. Understanding Vata's role is crucial in the study, as Madhumeha is classified under Vata-dominant Prameha conditions, where the interplay of doshas significantly affects treatment outcomes and metabolic control.
13) Rasashastra (Rasa-shastra, Rasa艣膩stra):
Rasa-Shastra is an ancient branch of Ayurveda that deals with medicinal chemistry and the preparation of metal and mineral-based medicines. The study of Swarna Vanga exemplifies Rasa-Shastra鈥檚 importance in developing alternative treatments for diabetes and evaluating their hypoglycaemic effects scientifically.
14) Discussion:
The discussion section of the study analyzes the findings in relation to existing knowledge, interpreting the effects of Swarna Vanga on blood sugar levels. This part emphasizes the significance of understanding results, implications for Ayurvedic practices, and potential avenues for further research and development.
15) Substance:
Substance refers to the physical matter, such as Swarna Vanga and mineral preparations, used in the study. Recognizing the exact nature of these substances is essential in understanding their pharmacological effects and potential therapeutic benefits within the framework of Ayurvedic medicine.
16) Ayurveda (膧yurveda, Ayus-veda):
Ayurveda is an ancient Indian system of medicine that emphasizes balance between body, mind, and spirit. The study's focus on Swarna Vanga and its application to treat Madhumeha illustrates Ayurveda's holistic approach to health and wellness, promoting natural remedies for metabolic conditions.
17) Shastra (艢膩stra):
Shastra means 'scripture' or 'science' in Sanskrit, referring to the body of knowledge in a particular field. In the context of the study, it highlights the textual basis of Rasa-Shastra and Ayurvedic medicine, underlining the tradition and scholarly aspects of healing practices.
18) Prakasha (Prak膩艣a, Pr膩k膩艣a):
Prakasa means 'manifestation' or 'light' in Sanskrit, often referring to illuminating knowledge. Its significance here relates to the historical texts that illuminate the principles of Ayurveda and Rasa-Shastra, guiding the understanding and utilization of Swarna Vanga in the treatment of metabolic disorders.
19) Glass:
Glass represents the material used in laboratory apparatus for conducting experiments, ensuring accuracy in measurements and results. The use of borosilicate glassware in the study underscores the importance of employing reliable materials to maintain the integrity of the research findings.
Other Science Concepts:
Discover the significance of concepts within the article: 鈥�鈥渆ffect of swarna vanga on madhumeha in albino rats鈥�鈥�. Further sources in the context of Science might help you critically compare this page with similair documents:
Control group, Experimental design, Statistical Significance, Treated group, Alloxan-induced diabetes, Mild effect, RESULTS AND DISCUSSION, Swarna Vanga, Ayurvedic therapeutic, Experimental animal, Laboratory diet, Prophylactic study, Albino rat, Madhumeha Prameha, Hypoglycaemic action, Blood sugar estimation.