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Significance of Wet granulation method

The wet granulation method is a crucial technique in pharmaceutical manufacturing that involves creating granules by mixing powder materials with a liquid binder. This process improves the flowability and compressibility of the powders, making it essential for tablet formulation. In this technique, dry ingredients are agglomerated into larger particles, often requiring drying and further processing into tablets. It is considered more complex and costly than direct compression methods but ensures better consistency and performance of the final pharmaceutical products.

The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.

The concept of Wet granulation method in scientific sources

Science Books

The Wet granulation method is a tablet formulation process that uses moisture to create granules from powder mixtures, essential for producing various tablet types, including chewable, by integrating drugs and excipients before compression.

Significance in Scientific journals, articles, etc.:

From: World Journal of Pharmaceutical Research

(1) A technique used to prepare tablets by mixing drug and excipients, and then granulating the mixture.[1] (2) A process used in tablet manufacturing that involves creating granules by adding a liquid binder to the powder mixture.[2] (3) A manufacturing method that combines powders with a liquid binder to form granules, which are then dried and processed into tablets.[3] (4) A technique used in the preparation of effervescent tablets which involves liquid to form granules.[4] (5) A process used to create granules from powders by adding a liquid binder to facilitate particle adhesion and improve drug handling.[5]

From: Ancient Science of Life

(1) A process used in pharmaceutical manufacturing to create granules using a moist massing process before compressing into tablets.[6]

From: International Ayurvedic Medical Journal

(1) A tablet manufacturing process that involves the addition of a liquid binder to powders, facilitating the formation of granules suitable for compression.[7]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.