Significance of Dosage level
Dosage level refers to the specific quantities of a substance administered in various studies to evaluate its effects and determine safety and efficacy. This includes varying amounts of drugs or extracts given to test subjects, such as mice or rats, to analyze their impact on health conditions or physiological responses. For example, different dosage levels of Crinum latifolium extract or tomato extract are assessed to understand their therapeutic effects while avoiding toxicity, making dosage levels a critical factor in experimental research.
Synonyms: Dosage strength, Dose level, Dose rate, Drug dose
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Dosage level in scientific sources
Dosage level is defined as the precise quantity of a substance given to ensure therapeutic benefits while minimizing the risk of toxicity, as reported by regional sources.
From: World Journal of Pharmaceutical Research
(1) The amount of a substance administered to subjects, with specific levels like 400 mg/kg and 600 mg/kg being evaluated in experiments.[1] (2) Refers to the specific quantity and frequency of administration of a drug; noted here for ketoprofen and its equivalence to other NSAIDs.[2] (3) Specific amounts of a drug given to subjects during a study to evaluate its effects.[3] (4) The specific amounts of the ethanolic extract administered to the mice, determined as 250mg/kg b.w and 500mg/kg b.w for evaluating the renal and hypoglycaemic activities.[4] (5) Refers to the quantity of tomato extract (in mg/kg) administered to mice in the study to evaluate its effects on chromosomal aberrations.[5]
From: AYU (Journal of Research in Ayurveda)
(1) Specified amounts of Makaradhwaja administered to rats, categorized into high, mid and low doses during the toxicity study.[6] (2) Refers to the specific amounts of Fumaria indica extract administered to rats in the study (100, 200, and 400 mg/kg/day), which were evaluated for their effects on cognitive functions.[7]
From: International Ayurvedic Medical Journal
(1) The different amounts of Vyoshadi Guggulu and Nagaradi Qwatha administered to the experimental groups, affecting the observed anti-inflammatory outcome.[8]
From: Ancient Science of Life
(1) The specific amounts of leaf extract administered to the rats during the experiment, measured in mg/kg, which include 100 mg/kg and 200 mg/kg.[9]
From: Journal of Ayurveda and Integrative Medicine
(1) Different amounts of the ethyl acetate fraction given to the testing groups: 25, 50, and 100 mg/kg.[10]
From: Ayushdhara journal
(1) Refers to the different amounts of Sivathai Chooranam administered to test subjects in the study to assess varying effects on pain and inflammation.[11]