Formulation and evaluation of herbal ointment with haridra, manjistha, mocharasa.
Journal name: Ayushdhara
Original article title: Formulation and evaluation of polyherbal ointment comprising haridra, manjistha and mocharasa
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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*Sarita Verma
M.D. Scholar, P.G Dept. Dravyaguna, Rishikul Campus Haridwar, Uttrakhand Ayurveda University
D. C. Singh
Proff. and H.O.D, P.G Dept. Dravyaguna, Rishikul Campus Haridwar, Uttrakhand Ayurveda University
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: Formulation and evaluation of polyherbal ointment comprising haridra, manjistha and mocharasa
Year: 2017
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Introduction
The increasing interest in herbal medicines, even in regions where modern medical treatments are readily available, has led to the development of various polyherbal formulations. These formulations leverage the bioactive components of plants, which provide natural remedies for numerous ailments. Among such formulations, herbal cosmetics have gained popularity for their beneficial properties in treating skin ailments. This study focuses on the formulation and evaluation of a polyherbal ointment containing Haridra (Curcuma longa), Manjistha (Rubia cordifolia), and Mocharasa (exudate from Salmali malabarica) due to their known antibacterial, anti-inflammatory, and wound healing properties.
Synergistic Active Ingredients
The polyherbal ointment developed combines the therapeutic properties of its key ingredients, each contributing distinct benefits. Haridra is renowned for its anti-inflammatory and wound healing properties, making it effective for treating skin conditions and promoting healing. Meanwhile, Manjistha serves as a powerful blood purifier and contributes antioxidant and immunomodulatory effects. Mocharasa adds moisturizing and nourishing qualities to the formulation. The synergistic action of these herbal components enhances the overall efficacy of the ointment, allowing it to address multiple skin concerns, including allergies, infections, and hypopigmentation.
Evaluation and Safety
The formulation underwent rigorous evaluation for its organoleptic and physicochemical properties like consistency, pH, and microbial contamination. Parameters such as the loss on drying, total ash, and solubility in alcohol and water were measured, with results falling within permissible limits. Toxicological assessments revealed that the ointment did not contain harmful heavy metals, indicating its safety for local application. Furthermore, irritancy tests showed no adverse reactions like erythema or edema, supporting its suitability for sensitive skin. These evaluations confirm the quality and safety of the polyherbal ointment, affirming its potential as a viable herbal cosmetic product.
Conclusion
The successful formulation of the polyherbal ointment exemplifies the potential of combining various herbal ingredients to enhance therapeutic effects on skin health. By leveraging the synergistic properties of Haridra, Manjistha, and Mocharasa, the ointment not only addresses skin ailments but also promotes overall skin wellness. Given its favorable safety profile and positive evaluations, this ointment represents a promising addition to the growing field of herbal cosmetics. Further research is encouraged to explore the clinical applications and benefits of this formulation in treating a broader range of skin conditions.
FAQ section (important questions/answers):
What is the main purpose of the polyherbal ointment?
The polyherbal ointment is formulated to heal various skin ailments, providing properties such as antibacterial, anti-inflammatory, antiseptic, and antioxidant effects. It incorporates natural herbal ingredients like Haridra, Manjistha, and Mocharasa for enhanced cosmetic benefits.
How were the extracts for the ointment prepared?
The extracts were prepared using traditional maceration and Ghana kalpana methods. Herbal materials were soaked in water, filtered, and reduced to obtain a concentrated aqueous extract containing the bioactive components necessary for the formulation.
What safety evaluations were conducted on the ointment?
The ointment underwent toxicological evaluations including heavy metal analysis and microbial testing. Results showed no detectable heavy metals above permissible limits, and there was an absence of harmful bacteria, indicating the formulation's safety for skin application.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Formulation and evaluation of herbal ointment with haridra, manjistha, mocharasa.�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Drug:
A substance used for medical treatment, especially a medicine. In Ayurveda, various herbal drugs like Haridra, Manjistha, and Mocharasa are used for their medicinal properties, as seen in the formulation of the polyherbal ointment.
2) Manjishtha (Manjistha, Mamjishtha):
Rubia cordifolia, known as Manjistha, is an Ayurvedic herb used for its blood purifying and skin healing properties. It is a component of the polyherbal ointment formulated in the study for its therapeutic benefits.
3) Haridra:
Curcuma longa, known as Haridra or Turmeric, is an Ayurvedic herb used for its anti-inflammatory, wound healing, and antiseptic properties. It is a key ingredient in the polyherbal ointment formulation.
4) Ghana:
An aqueous extract formed by reducing a herbal decoction until it reaches a semi-solid state. In the study, the Ghana of Haridra, Manjistha, and Mocharasa was used to prepare the polyherbal ointment.
5) Medicine:
A compound or preparation used for the treatment or prevention of disease. In the context of the study, herbal medicines like the polyherbal ointment provide therapeutic benefits for various skin ailments.
6) Kushtha (Kustha):
A term used in Ayurveda for skin diseases, particularly those that cause discoloration and lesions. Herbs like Haridra and Manjistha have therapeutic uses for Kustha.
7) Vrana:
Sanskrit for 'wound' or 'ulcer.' The polyherbal ointment in the study was evaluated for its wound healing properties, including its effectiveness in Vrana Ropana.
8) Samhita:
[see source text or glossary: Samhita]
9) Rakta:
[see source text or glossary: Rakta]
10) Roga:
[see source text or glossary: Roga]
11) Ayurveda (Ayus-veda):
A traditional system of medicine originating in India, focusing on holistic healing through herbal treatments and lifestyle practices. The polyherbal ointment study utilizes Ayurvedic principles and herbs.
12) Vyanga (Vyamga):
[see source text or glossary: Vyanga]
13) Rasa (Rasha):
In Ayurveda, it refers to the taste of a substance, which indicates its therapeutic effects. The study mentions the Rasa (taste) of herbs like Haridra and Manjistha to describe their properties.
14) Varṇya (Varnya):
One of the Ayurvedic properties meaning 'improving complexion.' The study notes that Haridra and Manjistha enhance skin complexion through their Varnya action.
15) Nature:
[see source text or glossary: Nature]
16) Karma (Karman):
[see source text or glossary: Karma]
17) Yoni (Yonin):
[see source text or glossary: Yoni]
18) Guna:
In Ayurveda, it refers to the qualities or attributes of a substance. The study describes the Guna (qualities) of Haridra, Manjistha, and Mocharasa used in the ointment.
19) Curcuma longa:
The scientific name for turmeric, known as Haridra in Ayurveda. It is a key ingredient in the polyherbal ointment due to its medicinal properties.
20) Pharmacological:
[see source text or glossary: Pharmacological]
21) Nadivrana (Nadi-vrana):
[see source text or glossary: Nadi-vrana]
22) Dravyaguna (Dravya-guna):
The study of medicinal properties of substances in Ayurveda. The researchers in the study are from the Dravyaguna Department, which focuses on evaluating herbal medicines.
23) Vidradhi:
[see source text or glossary: Vidradhi]
24) Visarpa:
[see source text or glossary: Visarpa]
25) Disease:
A disorder of structure or function in a living organism. The polyherbal ointment aims to treat skin diseases, leveraging the therapeutic properties of Ayurvedic herbs.
26) Ropana:
[see source text or glossary: Ropana]
27) Dosha (Dosa):
Fundamental bioelements in Ayurveda (Vata, Pitta, Kapha) which must be balanced for good health. Ingredients in the ointment are chosen for their ability to balance these Doshas.
28) Campu:
[see source text or glossary: Campu]
29) Shrava (Srava):
[see source text or glossary: Srava]
30) Nadi (Nadin):
[see source text or glossary: Nadi]
31) Vata:
One of the three Doshas in Ayurveda associated with air and space. The study mentions how the herbal ingredients help balance Vata Dosha, aiding in reducing pain and inflammation.
32) Rubia cordifolia:
The scientific name for Manjistha, an Ayurvedic herb known for its blood purifying and skin healing properties. It is a key ingredient in the polyherbal ointment.
33) Kushthaghna (Kusthaghna):
A term used in Ayurveda to denote substances that are effective against skin diseases. Herbs like Haridra and Manjistha have Kusthaghna properties.
34) Irritation:
A condition of inflammation or discomfort in a part of the body. The formulated ointment was evaluated to ensure it did not cause skin irritation.
35) Krimighna (Krmighna, Krimi-ghna):
A term in Ayurveda meaning 'antimicrobial or anti-parasitic'. Both Haridra and Manjistha possess Krimighna properties, providing antiseptic benefits in the ointment.
36) Colouring (Coloring):
Using natural substances to impart color. Haridra, due to its curcumin content, is widely used as a colouring agent in Ayurvedic preparations.
37) Snigdha:
An Ayurvedic term describing a substance that is oily and moist. Mocharasa has Snigdha properties that provide emollient effects in the ointment.
38) Shalmali (Salmali):
A tree known as Bombax malabaricum, whose resin, Mocharasa, is used in the polyherbal ointment for its therapeutic properties.
39) Kashya (Kasya):
[see source text or glossary: Kashya]
40) Aureus:
[see source text or glossary: Aureus]
41) Pitta:
One of the three Doshas in Ayurveda associated with fire and water. The ointment ingredients, like Haridra and Manjistha, help balance Pitta Dosha.
42) Dadru:
[see source text or glossary: Dadru]
43) Tikta:
[see source text or glossary: Tikta]
44) Virya:
[see source text or glossary: Virya]
45) Blood:
Manjistha is known for its blood purifying properties in Ayurveda, making it a vital component in the ointment aimed at improving skin health.
46) Guru:
[see source text or glossary: Guru]
47) Katu:
[see source text or glossary: Katu]
48) Yoga:
[see source text or glossary: Yoga]
49) Pama (Pama°):
[see source text or glossary: Pama]
50) Sushruta-samhita (Susruta-samhita):
[see source text or glossary: Sushruta-samhita]
51) Vranaropana (Vrana-ropana):
A term in Ayurveda referring to wound healing. The polyherbal ointment is formulated to promote Vrana-ropana using Haridra, Manjistha, and Mocharasa.
52) Raktasrava (Rakta-srava, Raktashrava):
[see source text or glossary: Rakta-srava]
53) Sandhaniya:
A quality in Ayurveda referring to the ability to promote binding or healing. This property is found in Mocharasa, used in the polyherbal ointment.
54) Netraroga (Netra-roga):
[see source text or glossary: Netra-roga]
55) Discussion:
Section of the paper where the authors interpret the results and explain the significance of their findings. It outlines the mode of action and effectiveness of the polyherbal ointment.
56) Vatarakta (Vata-rakta):
[see source text or glossary: Vata-rakta]
57) Yoniroga (Yoni-roga):
[see source text or glossary: Yoni-roga]
58) Inference:
The act of drawing conclusions from data. The study's inference highlights the efficacy and safety of the polyherbal ointment for treating skin ailments.
59) Picchila:
[see source text or glossary: Picchila]
60) Toxicity:
The degree to which a substance can harm humans or animals. The study ensured that the polyherbal ointment was non-toxic and safe for local application.
61) Turmeric:
Common name for Curcuma longa, known for its medicinal properties including anti-inflammatory and antioxidant effects. Turmeric is a key ingredient in the polyherbal ointment.
62) Madhura:
[see source text or glossary: Madhura]
63) Prameha:
[see source text or glossary: Prameha]
64) Kashaya (Kasaya):
[see source text or glossary: Kashaya]
65) Vipaka:
[see source text or glossary: Vipaka]
66) Cancer:
A disease characterized by uncontrolled cell growth. The study mentions that heavy metal contaminants in cosmetic products can potentially cause cancer.
67) Basti:
[see source text or glossary: Basti]
68) Netra:
[see source text or glossary: Netra]
69) Shotha (Sotha):
Ayurvedic term for inflammation or swelling. The ointment ingredients like Haridra and Manjistha help reduce Sotha due to their anti-inflammatory properties.
70) Ayus (Ayush):
[see source text or glossary: Ayush]
71) Tila:
[see source text or glossary: Tila]
72) Tree:
Refers to the source of some of the herbal ingredients. For example, resin from the Salmali tree is used to make Mocharasa, a key ingredient in the ointment.
73) Soil:
[see source text or glossary: Soil]
74) New Delhi:
Location of the Phytochemical Industries from which some of the herbal extracts were sourced for the polyherbal ointment study.
75) Raktatisara (Rakta-atisara):
[see source text or glossary: Rakta-atisara]
[Note: The above list is limited to 75. Total glossary definitions available: 127]
Other Science Concepts:
Discover the significance of concepts within the article: �Formulation and evaluation of herbal ointment with haridra, manjistha, mocharasa.�. Further sources in the context of Science might help you critically compare this page with similair documents:
Cosmetic, Mocharasa, Synergistic action, Pharmacological activity, Manjistha Rubia cordifolia, Skin ailments, Microbial Contamination, Toxicological evaluation, Organoleptic evaluation, Aqueous extract, Heavy metal contamination, Polyherbal ointment, Emollient, Haridra (Curcuma longa), Cosmeceutical, Levigation process.