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Standardization of 鲹ᲹԲ徱 cūrṇa: An ayurvedic preparation

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Journal name: Ancient Science of Life
Original article title: Standardization of 鲹ᲹԲ徱 cūrṇa: An ayurvedic preparation
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:

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Author:

Rupali Deshpande, Chandrashekara Shastry Shreedhara, Holavana Hally Nanjundaiah Setty Aswatha Ram


Ancient Science of Life:

(A quarterly multi-disciplinary scientific research journal in Ayurveda)

Full text available for: Standardization of 鲹ᲹԲ徱 cūrṇa: An ayurvedic preparation

Year: 2014

Copyright (license): CC BY-NC-SA


Summary of article contents:

Introduction

The standardization of herbal medicines is crucial for ensuring their quality, efficacy, safety, and reproducibility. This study focuses on the Ayurvedic classical preparation, 鲹ᲹԲ徱 cūrṇa (RC), which is used to treat various gastrointestinal and systemic disorders, including digestive impairment, fever, and asthma. Given the absence of established standards for RC, this investigation aimed to establish a set of quality parameters through the preparation and evaluation of the formulation.

Standardization of 鲹ᲹԲ徱 cūrṇa

The study involved the preparation of 鲹ᲹԲ徱 cūrṇa in three separate batches and conducted extensive evaluations based on physical characteristics, organoleptic attributes, and various physico-chemical parameters. The preparation followed the guidelines in The Ayurvedic Formulary of India, focusing on ensuring uniformity and potency in the final product. High-performance thin layer chromatography (HPTLC) analysis was performed to quantify curcumin, a key active component, with a recorded content of 0.335% w/w. The results indicated variable levels of heavy metals such as lead and cadmium, which exceeded the limits established by the World Health Organization, emphasizing the need for stringent quality control measures in herbal formulations.

Conclusion

The standardization process demonstrated the applicability of modern scientific techniques to establish quality parameters for 鲹ᲹԲ徱 cūrṇa, thereby providing a basis for developing pharmacopoeial standards. The findings underscore the importance of continuous evaluation of herbal products to ensure consumer safety and product efficacy. Overall, this study not only contributes to the standardization of RC but also highlights the broader significance of quality assurance in Ayurvedic herbal preparations.

FAQ section (important questions/answers):

What is 鲹ᲹԲ徱 cūrṇa used for in Ayurveda?

鲹ᲹԲ徱 cūrṇa is an Ayurvedic classical preparation used for treating various digestive disorders, fever, jaundice, anemia, and asthma. It aims to improve digestive function and overall well-being.

What methods were used to standardize 鲹ᲹԲ徱 cūrṇa?

Standardization involved in-house preparation of three batches of cūrṇa, which were evaluated based on organoleptic characters, physical and physico-chemical parameters, and High-Performance Thin Layer Chromatography for curcumin quantification.

What were the results of the physicochemical analysis?

The physicochemical analysis revealed parameters such as ash values, extractive values, loss on drying, as well as contamination levels of heavy metals, ensuring the quality and safety of the cūrṇa.

How is curcumin used as a marker in this study?

Curcumin, a key component found in turmeric, was identified using HPTLC as a marker to help quantify the active ingredient in 鲹ᲹԲ徱 cūrṇa. Its content was found to be 0.335% w/w.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Standardization of 鲹ᲹԲ徱 cūrṇa: An ayurvedic preparation�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Curna:
ūṇa refers to a powdered form of herbal preparation in Ayurveda. It signifies a method where plant materials are finely ground to create a powder that retains the medicinal properties of the ingredients, making it easier to administer and absorb while ensuring consistency in dosage and formulation.

2) Rajanyadi-curna:
鲹ᲹԲ徱-ūṇa is a specific Ayurvedic formulation, traditionally used for treating various digestive and respiratory disorders. This polyherbal preparation is comprised of multiple medicinal herbs, and its use places emphasis on holistic healing, combining various properties of each herb to enhance overall therapeutic effectiveness.

3) Rajanyadi:
鲹ᲹԲ徱 references the collection of herbs used within the 鲹ᲹԲ徱-ūṇa formulation. Ayurvedic texts describe 鲹ᲹԲ徱 as a combination of specific plants known for their synergistic effects on gastrointestinal health, which highlights the significance of multi-herb synergy that is central to Ayurvedic practices.

4) Science (Scientific):
Scientific refers to the application of systematic methodologies to validate research findings. The study of 鲹ᲹԲ徱-ūṇa emphasizes scientific approaches in assessing its efficacy and safety, bridging traditional knowledge with contemporary research techniques for better integration in modern medicine.

5) Quality:
Quality pertains to the standard of the herbal preparation in terms of efficacy, safety, and consistency. In Ayurvedic formulations like 鲹ᲹԲ徱-ūṇa, quality control is crucial to maintain therapeutic value, ensuring that the formulation meets the required specifications for its intended use.

6) Medicine:
Medicine in this context refers to the application of herbs and their extracts for therapeutic purposes. Ayurvedic medicine emphasizes natural healing methods, aiming to balance bodily systems and promote overall health through the use of formulations like 鲹ᲹԲ徱-ūṇa, which addresses specific ailments.

7) Drug:
A drug is a substance used to diagnose, treat, or prevent diseases. In Ayurveda, the term encompasses natural products like 鲹ᲹԲ徱-ūṇa, where plant-based ingredients are utilized for their pharmacological effects, demonstrating the intersection of traditional knowledge and contemporary understanding of drug efficacy.

8) Sarala (Sharala):
is one of the specific herbs included in the 鲹ᲹԲ徱-ūṇa formulation. Its unique properties contribute to the overall therapeutic action of the formulation. The selection of highlights the importance of each herb in the synergy that defines Ayurvedic treatments.

9) Water:
Water is an essential solvent in Ayurvedic practices, often used to prepare herbal extracts, decoctions, and infusions. In the context of 鲹ᲹԲ徱-ūṇa, the quality and properties of water used in various preparation processes may significantly affect the efficacy and bioavailability of the active components.

10) Prishniparni (Prsniparni, Prishni-parni):
ṛṣṇi貹ṇ� is another herb in the 鲹ᲹԲ徱-ūṇa formulation, known for its beneficial properties in Ayurvedic medicine. The inclusion of this plant underscores the formulation's complexity and the specific roles each herb plays in achieving therapeutic outcomes for digestive and respiratory issues.

11) Turmeric:
Turmeric, primarily known for its active compound curcumin, is integral to many Ayurvedic formulations, including 鲹ᲹԲ徱-ūṇa. Its anti-inflammatory, antioxidant, and antimicrobial properties contribute significantly to the overall health benefits, highlighting why it is a well-regarded herb across various traditional medicine systems.

12) Shreyasi (Sreyasi):
Śⲹī is one of the herbs utilized in 鲹ᲹԲ徱-ūṇa. Each herb in this formulation is selected for its specific health benefits, and the presence of Śⲹī suggests a careful selection aimed at addressing digestive disorders and respiratory health, fitting well within Ayurvedic principles.

13) Shatahva (Satahva):
Ś is a medicinal herb featured in the 鲹ᲹԲ徱-ūṇa formulation. Its inclusion represents the diversity of ingredients in Ayurvedic practices. The specific benefits of Ś enhance the synergistic effects targeting various health issues consistent with Ayurvedic treatments.

14) Curcuma longa:
Curcuma longa, commonly known as turmeric, is the primary source of curcumin, a compound with potent medicinal properties. Its relevance in Ayurvedic formulations like 鲹ᲹԲ徱-ūṇa is notable due to its wide-ranging health benefits, particularly in promoting digestive health and reducing inflammation.

15) Inflammation:
Inflammation is a biological response that can lead to various health issues. Ayurvedic formulations like 鲹ᲹԲ徱-ūṇa often target inflammation through their active ingredients, reflecting the holistic approach of Ayurveda to alleviate not just symptoms but also underlying causes of health problems.

16) Agnimandya (Agni-mandya, Agnimamdya):
ԾԻⲹ refers to a specific Ayurvedic concept of weakened digestive fire or enzyme activity, often leading to digestive disorders. 鲹ᲹԲ徱-ūṇa is indicated for this condition, showcasing how Ayurvedic formulations are tailored to address core imbalances within the body.

17) Discussion:
Discussion in this context entails exploring the results of the study on 鲹ᲹԲ徱-ūṇa, evaluating its efficacy, potential issues, and the relevance of findings in relation to both traditional practices and modern scientific inquiry, fostering a dialogue on enhancing herbal medicine standards.

18) Depression:
Depression is a mental health condition that can be influenced by biological, psychological, and environmental factors. While 鲹ᲹԲ徱-ūṇa primarily addresses physical health problems, holistic Ayurveda recognizes the interconnectedness of mental and physical dimensions in overall wellness and treatment strategies.

19) Kantakari (Kamtakari):
ṇṭ, an alternative spelling of Kaṇṭakārī, emphasizes the importance of this herb in traditional Ayurvedic formulations. Its presence alongside other significant herbs denotes the collaborative interaction of multiple ingredients designed to target various health issues holistically.

20) Ayurveda (Ayus-veda):
Ayurveda is a traditional Indian system of medicine that emphasizes balance and the use of natural remedies. 鲹ᲹԲ徱-ūṇa is an embodiment of Ayurvedic principles, utilizing a thoughtful combination of herbs to promote health and treat specific conditions, reflecting its holistic approach.

21) Devadaru (Deva-daru):
ٱ𱹲 is another herb featured in the formulation of 鲹ᲹԲ徱-ūṇa, recognized for its unique medicinal properties. Its inclusion points to Ayurveda's meticulous selection of plant materials based on their individual and synergistic effects on health, particularly for gastrointestinal wellness.

22) Parimana:
ʲṇa refers to the measurement of size or quantity within the context of herbal preparations. In Ayurveda, accurate measurement ensures consistency in formulations like 鲹ᲹԲ徱-ūṇa, essential for maintaining efficacy and reliability of therapeutic outcomes for patients.

23) Atisara:
پ signifies the Ayurvedic term for diarrhea. 鲹ᲹԲ徱-ūṇa is known to address this condition, demonstrating the formulation's capability to normalize digestive functions while providing a natural solution to digestive disturbances commonly encountered in patients.

24) Rajani:
Rajani, closely linked with Rajanī, underscores the importance of herb nomenclature in Ayurvedic medicine. The specific attributes or benefits associated with Rajani highlight the comprehensive knowledge Ayurvedic practitioners possess regarding the therapeutic usages of particular plant species.

25) Brihati (Brhati):
ṛhī is an essential herb in 鲹ᲹԲ徱-ūṇa noted for its health-promoting properties. The use of ṛhī reflects the emphasis within Ayurveda on utilizing specific plants to enhance the overall effectiveness of a formulation targeted at addressing particular health ailments.

26) Gandha (Gamdha):
Gandha translates to 'odor' or 'scent' in Ayurveda, reflecting an integral part of herbal evaluations. The aroma contributes to the sensory experience of herbal formulations like 鲹ᲹԲ徱-ūṇa, serving as a quality indicator that can impact the perception and acceptance of the medicine.

27) Bitter:
Bitter is a taste profile significant in Ayurveda, often associated with detoxifying and digestive-enhancing properties of herbs. In formulations like 鲹ᲹԲ徱-ūṇa, the presence of bitter components is purposeful, aimed at promoting digestion and metabolic functions within the body.

28) Reason:
Reason in this context pertains to the rationale behind selecting specific herbs in 鲹ᲹԲ徱-ūṇa. Each ingredient is chosen based on traditional knowledge and contemporary research, ensuring the formulation works effectively in treating the intended health issues.

29) Kamala (Kama-la):
refers to jaundice in Ayurvedic terminology. The presence of this condition in the context of 鲹ᲹԲ徱-ūṇa illustrates the formulation's therapeutic aims, which are designed to address liver function and improve overall health by mitigating symptoms associated with jaundice.

30) Jvara:
Jvara denotes fever within Ayurvedic discourse, highlighting another condition that 鲹ᲹԲ徱-ūṇa is used to address. By incorporating herbs traditionally recognized for their antipyretic properties, the formulation showcases its multi-faceted approach to treating common ailments.

31) Shvasa (Svasa, Svasha):
Ś translates to 'respiration' or 'breath' in Ayurveda, representing respiratory issues like asthma. 鲹ᲹԲ徱-ūṇa's application in treating these conditions emphasizes its role in improving respiratory health using synergistic effects of its herbal components.

32) Pandu (Pamdu, Pamde):
ṇḍ refers to anemia, an important condition addressed in Ayurvedic practice. The formulation 鲹ᲹԲ徱-ūṇa is relevant here as it combines herbs believed to improve blood health, thus pointing to the holistic treatment strategies prevalent in Ayurveda.

33) Varna:
ղṇa means 'color', which is particularly significant in the organoleptic evaluation of herbal products. The color of 鲹ᲹԲ徱-ūṇa can indicate its quality and freshness, and evaluating this aspect ensures that the preparation meets established standards for Ayurvedic medicines.

34) Cina:
China signifies the origin of many herbal and medicinal practices, including Traditional Chinese Medicine (TCM), which, like Ayurveda, utilizes extensive herbal knowledge. The comparative insights from different traditions can enrich understanding and applications in herbal treatments worldwide.

35) Ruci:
Ruci refers to 'taste' within Ayurvedic terminology, which plays a critical role in the holistic evaluation of herbal preparations. The taste of 鲹ᲹԲ徱-ūṇa is not only indicative of herb quality but also correlates with its therapeutic properties and patient acceptability.

36) Daru:
translates to 'wood' or 'tree' in Sanskrit and may refer specifically to certain plant parts used in Ayurvedic formulations. The incorporation of such parts in 鲹ᲹԲ徱-ūṇa emphasizes the diverse sources of herbal ingredients leveraged for therapeutic purposes, demonstrating Ayurveda’s profound connection with nature.

Other Science Concepts:

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Discover the significance of concepts within the article: �Standardization of Rajanyadi curna: An ayurvedic preparation�. Further sources in the context of Science might help you critically compare this page with similair documents:

Active principle, Ayurvedic medicine, High performance thin layer chromatography, Microscopic evaluation, Phytochemical analysis, Organoleptic evaluation, Physicochemical characteristics, Heavy metal, Alcoholic extract, Pharmacopoeial standard, Curcumin content, Quality control process, Analytical specifications, Standardization of herbal medicine.

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