Physicochemical analysis of Mandura Bhasma, an iron-based medicine.
Journal name: Ancient Science of Life
Original article title: Physicochemical characterization of an Iron based Indian traditional medicine: Mandura Bhasma
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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Sachin B. Mulik, C. B. Jha
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Physicochemical characterization of an Iron based Indian traditional medicine: Mandura Bhasma
Year: 2011
Copyright (license): CC BY-NC-SA
Summary of article contents:
Introduction
Ayurveda, a traditional Indian system of medicine, utilizes metallic and mineral-based preparations known as bhasma, which are fine powders obtained through a process of calcination. Mandura bhasma, an iron-based preparation, is well-regarded for its therapeutic applications in conditions such as anemia, jaundice, and skin diseases. This study focuses on the physicochemical characterization of raw Mandura and its processed form, Mandura bhasma, employing advanced analytical techniques to establish quality control measures essential for standardization. The authors aimed to document the transformation of raw Mandura into a bioavailable form, thereby ensuring consistent efficacy and safety in therapeutic applications.
Transformation During Calcination
One of the significant findings of this study is the transformation of chemical compounds during the calcination process. The analytical methods, including X-ray diffraction (XRD) and scanning electron microscopy (SEM), revealed that raw Mandura primarily consisted of iron silicate (Fe₂SiO�), while Mandura bhasma contained iron oxide (Fe₂O�) and silicon dioxide (SiO�). This change signifies that the calcination process converts a complex compound into simpler, more bioavailable forms, reducing particle sizes from 10-2 microns in the raw material to 200-300 nanometers in the bhasma. Such a reduction in particle size may enhance absorption and assimilability within the body, contributing to the increased efficacy of Mandura bhasma as a therapeutic agent.
Conclusion
The study concludes that the specific calcination method used in preparing Mandura bhasma not only alters its chemical composition but also significantly reduces particle size, potentially improving its therapeutic efficacy. This research provides critical data that could aid in the standardization of Mandura bhasma, emphasizing the need for rigorous quality control in the preparation of traditional Ayurvedic medicines. The findings underscore the importance of employing modern analytical techniques to understand better how these time-honored practices can produce effective medicinal products, thereby bridging ancient wisdom with contemporary scientific inquiry.
FAQ section (important questions/answers):
What is Mandura Bhasma and its significance in Ayurveda?
Mandura Bhasma is an iron-based Ayurvedic preparation known for treating conditions like anemia, jaundice, and skin diseases. It is made through a process involving purification, calcination, and the incorporation of plant extracts.
What methods were used to analyze Mandura Bhasma in the study?
The study utilized sophisticated techniques such as X-ray diffraction (XRD) and scanning electron microscopy (SEM) to characterize raw and processed Mandura, assessing its physical and chemical properties, including particle size reduction.
How does the preparation process of Mandura affect its properties?
The preparation process involves a sequence of purification and calcination, transforming raw Mandura's complex compounds into simpler, nano-sized particles, enhancing its bioavailability and therapeutic effectiveness.
What are the quality control tests used for Mandura Bhasma?
Quality control tests for Mandura Bhasma included parameters like lusterlessness, rekhapurnatvam (filling of grooves), and varitaratavam (floating on water), ensuring the product meets Ayurvedic standards for efficacy and safety.
Other Science Concepts:
Discover the significance of concepts within the article: �Physicochemical analysis of Mandura Bhasma, an iron-based medicine.�. Further sources in the context of Science might help you critically compare this page with similair documents:
Rasashastra, Therapeutic use, Standardization of preparation, X-ray diffraction, Bhasma preparation, Scanning Electron Microscopy, Particle size reduction, Physicochemical characterization, Mandura Bhasma, Ayurvedic classic, Calcination process, Reproducible quality, Quality Control Test.