Significance of Ursolic acid
Ursolic acid is a pentacyclic triterpenoid carboxylic acid primarily isolated from Clerodendrum phlomidis and Stachytarpheta jamaicensis. It is recognized for a range of pharmacological benefits, including antiobesity, gastroprotective, anti-inflammatory, antiviral, anticancer, and antioxidant properties. This compound demonstrates potential therapeutic effects such as improving insulin levels, enhancing skin moisture retention, and promoting bone formation. Ursolic acid’s diverse health benefits make it a significant focus in natural medicine and pharmacology.
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The concept of Ursolic acid in scientific sources
Ursolic acid, a pentacyclic triterpenoid found in Clerodendrum phlomidis, is noted for its antioxidant and pharmacological properties, including potential therapeutic effects and activity against obesity.
From: World Journal of Pharmaceutical Research
(1) A beneficial terpenoid found in L. heterophylla and L. rugosa, valued for its health properties.[1] (2) A compound isolated from petroleum ether extract, identified for its cytotoxic potential based on IR and NMR analysis.[2] (3) A triterpenoid isolated from flowers alongside oleanolic acid, contributing to the medicinal properties attributed to the plant.[3] (4) A triterpene compound with anti-inflammatory properties that enhances skin moisture retention and may have anti-aging effects.[4] (5) An active constituent found in many plants with functions including anti-inflammatory, anti-virus, anticancer, and anti-obesity properties, and contributes to the promotion of bone formation.[5]
From: Journal of Ayurveda and Integrative Medicine
(1) A compound found in holy basil (Tulsi) recognized for its strong antiviral activities, particularly against SARS-CoV-2.[6]