Significance of LD50
LD50, or the median lethal dose, is a standard measure in toxicology that indicates the amount of a substance required to kill 50% of a test population. It is commonly used to assess the potency of toxins, including snake venom, and the safety of various substances in studies involving acute toxicity. The LD50 value helps gauge the toxicity level of different extracts and is crucial in determining the effectiveness of antidotes and the safety profiles of compounds tested on rodents and other animals.
Synonyms: Lethal dose, Median lethal dose, Toxic dose
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The concept of LD50 in scientific sources
LD50, or the median lethal dose, is a crucial metric in toxicity testing for A. speciosa, signifying the dosage required to kill 50% of test subjects, thus providing insights into its safety and toxicological profile.
From: The Malaysian Journal of Medical Sciences
(1) This is a dose of a substance that causes death in 50% of a population of test animals, and it was determined for pulegone through oral and dermal routes.[1]