Significance of Histological subtype
Histological subtype refers to different classifications of tumors based on their microscopic structure and characteristics. This classification influences the expression of important proteins such as Bcl-2 and Bax and encompasses various forms of cancer, including meningiomas and myofibroblastomas, which are further categorized into five subtypes: classical, epithelioid, collagenised, cellular, and infiltrative. This classification is significant for understanding the biological behavior of tumors and their treatment responses.
Synonyms: Histological classification, Category, Classification, Variety, Group, Type, Form
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The concept of Histological subtype in scientific sources
Histological subtype categorizes cancer types based on microscopic structure and histological characteristics, impacting gene and protein expression, particularly influencing the expression of Bcl-2 and Bax, which are crucial in cancer biology.
From: The Malaysian Journal of Medical Sciences
(1) The expression of serum beta-hCG is not associated with any specific ones, although some authors have found that this phenomenon is more characteristic of adenocarcinoma.[1] (2) These are different classifications of epithelial ovarian cancer based on histopathology, immunohistochemistry, genetic alterations, and the molecular mechanisms involved.[2] (3) Histological subtypes refer to the different classifications of cancer based on the microscopic appearance of the cells, and YOCRC demonstrated more specific subtypes such as mucinous and signet ring carcinoma.[3] (4) The classification of myofibroblastomas into five subtypes: classical, epithelioid, collagenised, cellular, and infiltrative.[4] (5) Histological subtype refers to the classification of tumours based on their microscopic structure, influencing how Bcl-2 and Bax are expressed.[5]