Significance of Genetic instability
Genetic instability is characterized by fluctuations in the genetic makeup of organisms such as Rhizobium strains, affecting their nitrogen-fixing abilities. It also involves a high mutation rate within genomes, commonly observed in cancer cells, which can lead to tumor progression and evolution. Additionally, genetic instability can be linked to extra-chromosomal elements like small circular DNAs, which can induce further mutations and are associated with cancer development.
Synonyms: Genetic variability, Genetic disorder, Genomic instability, Hereditary mutations, Chromosomal instability, Genetic alteration
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The concept of Genetic instability in scientific sources
Genetic instability denotes fluctuations in the genetic makeup of organisms, like Rhizobium strains affecting nitrogen fixation, and the high mutation rates in cancer cells, leading to tumor growth and evolution.
From: The Malaysian Journal of Medical Sciences
(1) A condition often associated with the presence of extra-chromosomal elements like small circular DNAs, which may lead to mutations and cancer.[1]