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Significance of Chromosomal instability

Chromosomal instability is characterized by high rates of genetic alterations in a cell's chromosomes. This instability can result in significant consequences, particularly the development of diseases like cancer. The variations in chromosome structure and number are critical factors in understanding the mechanisms behind tumorigenesis and other genetic disorders, highlighting the importance of studying chromosomal instability in the context of disease prevention and treatment.

Synonyms: Genomic instability, Chromosomal aberration, Genetic instability, Chromosome instability

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The concept of Chromosomal instability in scientific sources

Science Books

Chromosomal instability indicates a high frequency of genetic alterations in chromosomes, significantly contributing to the development of diseases like cancer, as it disrupts normal cell function and genetic stability.

Significance in Scientific journals, articles, etc.:

From: World Journal of Pharmaceutical Research

(1) A hallmark of cancer characterized by an increased rate of chromosomal alterations, linked to DNA hypomethylation.[1] (2) The presence of high rates of genetic alterations within a cell's chromosomes, which can lead to diseases such as cancer.[2]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.