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Significance of Fatal Dose

Fatal Dose refers to the specific amount of a substance that can result in death if ingested or administered. It highlights the importance of precise dosing, particularly for toxic substances like Rakta Chitrak, Gunja, and Vatsanabha, among others. Various plants and compounds have defined fatal doses, such as Dhatura seeds (50-125) and strychnine (15-50 mg), illustrating their lethal potential. Understanding and respecting these quantities is vital for safety and medical treatment, as they can lead to serious health risks or death.

Synonyms: Toxic dose, Overdose, Lethal dosage, Lethal dose

The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.

The concept of Fatal Dose in scientific sources

Science Books

Fatal Dose is defined as the lethal quantity of substances like abrin, ranging from 60 to 120 mg, and Bhallataka, quantified at 5 to 10 grams, highlighting critical safety risks associated with these toxins.

Significance in Scientific journals, articles, etc.:

From: World Journal of Pharmaceutical Research

(1) The amount of snake venom that can be lethal to humans, specific in milligrams for different species of snakes.[1] (2) Fatal dose indicates the quantity of a substance, specifically Vatsanabha, that can result in death, as specified in toxicological references.[2] (3) The amount of a substance that can result in death, referenced regarding Vatsanabha (Aconitum ferox).[3] (4) The amount of Croton oil or seeds that can lead to death, specified as 20 drops of oil or 1-2 ml of oil, and 4-5 seeds.[4] (5) The amount of venom that can cause death, which varies depending on factors such as age and health status.[5]

From: International Ayurvedic Medical Journal

(1) The amount of a substance that can lead to death; for Bhallataka, this is identified as 5 to 10 grams or about 10 seeds.[6] (2) The quantity of Gunja seeds or extract considered sufficient to cause death, which is noted to be 90-120 mg by injection or 1-2 crushed seeds by mouth.[7] (3) The quantity of Dhatura or its compounds that can lead to serious or lethal outcomes, specified as approximately 60 to 100 seeds.[8] (4) The amount of Jaypal oil or seeds that can lead to mortality, stated as 20 drops of oil or 4 seeds.[9] (5) The text specifies that one gram of the root or 20 drops of tincture can be fatal, highlighting the dangerous potency of Vatsanabha.[10]

From: Ayushdhara journal

(1) The amount of strychnine considered lethal, typically between 15-50 mg for adults, illustrating the high toxicity of Kuchala.[11]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.

Plural form: Fatal doses.