Significance of Cell apoptosis
Cell apoptosis is the process of programmed cell death critical for eliminating damaged or unwanted cells, such as cancer cells. It can be influenced by various substances, including anticancer drugs and plant extracts. Studies indicate that factors like curcumin and Ocimum gratissimum extract significantly enhance apoptosis in cancer cells, particularly in MCF-7 cells. Additionally, the role of proteins like caspase-3 in this process is vital, as well as the influence of nitric oxide levels on cell survival.
Synonyms: Cell death, Programmed cell death, Cellular apoptosis, Cell suicide, Apoptosis
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The concept of Cell apoptosis in scientific sources
Cell apoptosis is a programmed cell death process influenced by factors like curcumin concentration and anticancer drugs, evidenced by increased apoptosis in MCF-7 cells treated with Ocimum gratissimum extract, showcasing its potential as an anticancer agent.
From: The Malaysian Journal of Medical Sciences
(1) Cell apoptosis is a process of programmed cell death characterized by cytoplasmic membrane blebbing and DNA fragmentation.[1] (2) This is the process of programmed cell death, and it is a vital mechanism for eliminating damaged or unwanted cells, such as cancer cells.[2] (3) This is the process of programmed cell death, and caspase-3 is a coding protein that plays a role in the execution of this process and is inhibited by the Kencur extract.[3] (4) Andrographolide suppressed cell proliferation by inducing cytotoxicity, evoking cell apoptosis, and activating caspase-3/9 activities in human colon cancer cells.[4] (5) This is the process of programmed cell death that is induced by certain substances, such as extracts from specific plants, and is a key mechanism in the treatment of cancer.[5]