Significance of Programmed cell death
Programmed cell death, also known as apoptosis, is a highly regulated process that allows for the controlled elimination of unnecessary or damaged cells within an organism. It plays a crucial role in various contexts, including cancer treatment, where it helps eliminate cancerous cells, and in maintaining cellular homeostasis. This process is triggered by external stimuli and serves essential functions during development and under pathological conditions. Understanding programmed cell death is vital for developing effective therapies, particularly in oncology.
Synonyms: Apoptosis, Cell death, Cellular apoptosis, Cell suicide, Cellular self-destruction
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The concept of Programmed cell death in scientific sources
Programmed cell death is a crucial developmental process that can be disrupted by Cyclophosphamide, potentially resulting in structural abnormalities in embryos, highlighting its significance in normal cellular development.
From: The Malaysian Journal of Medical Sciences
(1) Programmed cell death, known as pyroptosis, is also a result of inflammasome activation, which is pro-inflammatory and involves the maturation of interleukin-1β and interleukin-18.[1] (2) This is a natural process where cells self-destruct in a controlled manner, and it is also known as apoptosis.[2] (3) This is a regulated process of cellular self-destruction that is essential for development and eliminating damaged or unwanted cells, like cancer cells.[3] (4) This is a process of cell self-destruction, and it is a cellular change that is a potential pathophysiological mechanism in PROM.[4] (5) This is a process by which cells self-destruct, and it is reviewed in the context of understanding the mechanisms behind this specific process.[5]