Significance of Apoptotic activity
Apoptotic activity is defined as the ability of a substance to induce programmed cell death, which is essential for eliminating cancerous cells during therapy. Various studies have demonstrated that certain compounds, including methanol extracts of Albizia lebbeck and various polyphenols, can effectively trigger apoptosis in cancer cells. This ability can differ among different tumor cell types and has been evaluated in specific cell lines, highlighting the importance of apoptotic activity in cancer treatment strategies.
Synonyms: Apoptotic response, Apoptotic process, Cell death, Apoptosis, Programmed cell death, Mitochondrial pathway, Caspase activation, Apoptotic signaling
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The concept of Apoptotic activity in scientific sources
Apoptotic activity is the capacity of compounds to induce programmed cell death, crucial for eliminating cancer cells. Evaluations in THP-1 cell lines highlight its significance in therapeutic applications for cancer treatment.
From: The Malaysian Journal of Medical Sciences
(1) The degree of programmed cell death occurring within cells, which can vary between different types of tumour cells.[1]