Significance of Alloxan-diabetic rats
Alloxan-diabetic rats are rats that have been chemically induced with diabetes through an Alloxan injection. This model is widely used in experiments to assess the antihyperglycemic effects of various treatments, including plant extracts and herbal remedies. Studies have employed Alloxan-diabetic rats to evaluate the hypoglycemic activity of substances like Arani and the stem bark exudates, as well as to investigate the potential antidiabetic properties of herbal extracts such as Bhringraj.
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The concept of Alloxan-diabetic rats in scientific sources
Alloxan-diabetic rats are specifically induced with diabetes through Alloxan injections, creating a model to study and evaluate the antihyperglycemic effects of plant extracts and treatments, particularly focusing on stem bark exudates.
From: World Journal of Pharmaceutical Research
(1) A model used in pharmacological studies to assess potential antidiabetic effects of herbal extracts like those from Bhringraj.[1] (2) Rats induced with diabetes by Alloxan injection, used in experiments to evaluate the antihyperglycemic effects of plant extracts.[2] (3) A model used in this study to evaluate the antihyperglycemic activity of the stem bark exudates, where diabetes is induced using Alloxan.[3]
From: Ancient Science of Life
(1) A specific experimental model used to simulate diabetes in rats to study the hypoglycaemic effects of Arani.[4] (2) Rats that were induced to have diabetes through a chemical called alloxan, used in the study to evaluate the effectiveness of treatments.[5] (3) Rats that have been induced to have diabetes by administering alloxan, used as a model for studying diabetes treatments.[6]
From: Journal of Ayurveda and Integrative Medicine
(1) A specific model of diabetes used in experiments to study the effects of treatments on diabetes.[7]