Therapeutic potential of Argemone maxicana in Ayurveda and research
Journal name: World Journal of Pharmaceutical Research
Original article title: Therapeutic potential of argemone maxicana l. in the perspective of ayurveda and recent research activities
The WJPR includes peer-reviewed publications such as scientific research papers, reports, review articles, company news, thesis reports and case studies in areas of Biology, Pharmaceutical industries and Chemical technology while incorporating ancient fields of knowledge such combining Ayurveda with scientific data.
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Ravi Kaushik, Chandan Singh, Manoj Adlakha and Dr. Rajendraprasad Purvia
World Journal of Pharmaceutical Research:
(An ISO 9001:2015 Certified International Journal)
Full text available for: Therapeutic potential of argemone maxicana l. in the perspective of ayurveda and recent research activities
Source type: An International Peer Reviewed Journal for Pharmaceutical and Medical and Scientific Research
Doi: 10.20959/wjpr202215-26022
Copyright (license): WJPR: All rights reserved
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Summary of article contents:
Introduction
Argemone mexicana, commonly known as Mexican poppy or prickly poppy, is a medicinal plant belonging to the Papaveraceae family, recognized for its extensive therapeutic potential. In traditional medicine, particularly in Ayurveda, it has been documented under various local names and is implied to possess significant healing properties for a wide range of ailments, including microbial infections, skin diseases, and gastrointestinal disorders. Recent scientific research supports its traditional uses, corroborating its antimicrobial, anti-inflammatory, anti-diabetic, and wound healing properties.
Antioxidant Activity
One of the notable therapeutic attributes of Argemone mexicana is its antioxidant activity, which plays a vital role in combating oxidative stress caused by free radicals. Research indicates that various extracts of the plant demonstrate strong free radical scavenging abilities. For instance, studies have shown that the ethanolic extract exhibited 87.1% hydrogen peroxide scavenging activity, comparable to the standard antioxidant ascorbic acid. Additionally, methanolic extracts from different parts of the plant displayed significant radical scavenging activity, demonstrating its potential to mitigate oxidative damage associated with various diseases such as cancer and cardiovascular diseases.
Anti-Diabetic Properties
Argemone mexicana has also been traditionally used for treating diabetes, and numerous studies confirm its anti-diabetic effects through various mechanisms. Research has demonstrated that aqueous extracts significantly reduce blood glucose levels in diabetic models, indicating a potent hypoglycemic activity. Investigations into the extract's mechanisms reveal that it enhances the activity of antioxidant enzymes, suggesting that phytochemicals within the plant may improve glucose metabolism and mitigate oxidative stress in diabetic conditions. These findings support the traditional folk usage of the plant in managing diabetes and its complications.
Wound Healing and Anti-Inflammatory Effects
The plant is recognized for its wound healing properties; multiple studies have analyzed its effectiveness in treating wounds and reducing inflammation. Extracts from Argemone mexicana have shown significant results in various wound healing models, outperforming some standard medicinal agents. The pharmacological activities have been attributed to bioactive compounds such as flavonoids and alkaloids, which contribute to both wound contraction and epithelialization processes. Furthermore, anti-inflammatory studies indicate that the plant's extracts exhibit substantial anti-inflammatory effects, providing evidence for its traditional use in alleviating inflammation-related disorders.
Conclusion
In summary, Argemone mexicana is a valuable medicinal plant with a robust pharmacological profile validated by both traditional and contemporary scientific studies. Its therapeutic potential spans across antioxidant activity, diabetes management, and effective wound healing, showcasing its multidimensional applications in treating various ailments. The growing body of research underscores the need for advanced studies to further elucidate its mechanisms and expand its therapeutic applications, solidifying its role in modern and traditional medicine alike.
FAQ section (important questions/answers):
What is Argemone mexicana and its common names?
Argemone mexicana, also known as Mexican poppy or Prickly poppy, is a medicinal plant belonging to the Papaveraceae family, recognized for its therapeutic potential.
What diseases can Argemone mexicana help treat?
It has traditionally been used for treating ulcers, wounds, skin diseases, malaria, rheumatism, jaundice, and microbial infections among other ailments.
What pharmacological activities are associated with Argemone mexicana?
Argemone mexicana exhibits various pharmacological activities including antimicrobial, anti-inflammatory, analgesic, anti-ulcer, wound healing, and antioxidant properties.
How does Argemone mexicana contribute to antioxidant activity?
The plant contains polyphenol compounds that act as natural antioxidants, helping to neutralize free radicals associated with diseases like cancer and cardiovascular issues.
What are the possible anti-diabetic effects of Argemone mexicana?
Studies have shown that Argemone mexicana extracts can significantly reduce blood glucose levels and enhance antioxidant enzyme activity in diabetic models.
What misconceptions exist about Argemone mexicana?
There is a misconception that Argemone mexicana is poisonous and causes epidemic dropsy, but this is linked to the adulteration of edible oils, not the plant itself.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Therapeutic potential of Argemone maxicana in Ayurveda and research�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Activity:
Activity refers to the specific functions or effects exhibited by compounds or extracts, particularly in the context of pharmacology. It encompasses various biological responses such as antimicrobial, anti-inflammatory, or analgesic effects, indicating the therapeutic potential of natural products in treating diseases and conditions.
2) Study (Studying):
Study refers to systematic investigations conducted to gather data and analyze specific aspects. In this context, studies related to Argemone mexicana explore its pharmacological properties, efficacy in treating ailments, and validate its traditional uses. Research contributes to evidence-based medicine and enhances understanding of therapeutic applications.
3) Disease:
Diseases encompass a broad range of health conditions, including infections, chronic illnesses, and inflammatory diseases. The text highlights Argemone mexicana's role in managing a variety of diseases, such as peptic ulcers and skin conditions, showcasing its vast therapeutic potential and supporting traditional medical practices.
4) Ulcer:
Ulcers refer to open sores on the skin or mucous membranes. The text highlights different studies investigating the antiulcer activity of Argemone mexicana, indicating its traditional use for healing while supporting a broader understanding of therapeutic applications in ulcer management.
5) Flavonoid:
Flavonoid is a diverse group of plant secondary metabolites known for their antioxidant properties. The text discusses the presence of flavonoids in Argemone mexicana, which contribute to its health benefits, particularly in combating oxidative stress and supporting overall health through their biological activity.
6) Drug:
Drug refers to any substance used to diagnose, cure, treat, or prevent disease. The text emphasizes the importance of traditional medicinal plants like Argemone mexicana in drug development, highlighting their potential integration into modern pharmaceutical practices for treating various ailments due to their biological activities.
7) Antibiotic (Antibacterial):
Antibiotic refers to substances that inhibit the growth of bacteria. The text focuses on the potential of Argemone mexicana as an antibacterial agent, underlining the increasing need for research to find effective antibiotics from natural sources.
8) Viru:
Although 'Viru' appears to be a typographical error likely referring to 'virus', it suggests the importance of the immune response to viral infections. The text mentions Argemone mexicana's antiviral properties, highlighting its potential to combat viral diseases and support immune function.
9) Pharmacological:
Pharmacological relates to the study of how drugs interact with biological systems, impacting medicinal use. The text discusses the pharmacological profile of Argemone mexicana, including its various therapeutic effects, thus emphasizing the importance of understanding these properties for effective drug formulation and usage.
10) Phytochemical:
Phytochemical refers to bioactive compounds obtained from plants, known for their health benefits. The text discusses various phytochemicals in Argemone mexicana, responsible for its therapeutic effects such as antioxidant, antibacterial, and anti-inflammatory properties, confirming its value in natural medicine.
11) Ayurveda (Ayus-veda):
Ayurveda is an ancient Indian system of medicine that emphasizes natural healing through diet, herbs, and lifestyle. The text relates Argemone mexicana to Ayurvedic practices, highlighting its historical medicinal uses and philosophical underpinnings that value holistic health approaches.
12) Medicine:
Medicine refers to the science and practice of diagnosing, treating, and preventing illness. The text emphasizes the role of Argemone mexicana in traditional and modern medicine, showcasing its potential in addressing various health issues and its significance in the field of medicinal research.
13) Species:
Species refers to a distinct group of organisms that share common characteristics. In the context of Argemone mexicana, the species is highlighted for its uniqueness as a potent medicinal plant within the Papaveraceae family, showcasing its therapeutic potential and biodiversity.
14) Inflammation:
Inflammation is a biological response to harmful stimuli, causing redness, swelling, and pain. The text discusses the anti-inflammatory properties of Argemone mexicana, supporting its traditional use in treating various inflammatory conditions, thus indicating its potential for therapeutic application.
15) Science (Scientific):
Scientific pertains to methods based on observation and experimentation. The text emphasizes the importance of scientific studies validating the medicinal properties of Argemone mexicana, bridging traditional knowledge with modern research to enhance understanding of its therapeutic potential.
16) Dravyaguna (Dravya-guna):
Dravyaguna is a branch of Ayurvedic science focusing on the properties and effects of medicinal herbs. The text mentions Dravyaguna in relation to Argemone mexicana, emphasizing its role in Ayurvedic treatments and showcasing the integration of traditional practices with scientific validation.
17) Rajasthan:
Rajasthan is a state in India, known for its rich cultural heritage and traditional medicinal practices. The text acknowledges Dr. S R Rajasthan Ayurved University, linking the region’s historical use of plants like Argemone mexicana to contemporary research in Ayurveda and herbal medicine.
18) Animal:
Animals refer to multi-cellular organisms that can be used in pharmacological research. The study of Argemone mexicana's effects on animal models is critical for understanding its therapeutic implications before human trials, aiding in validating traditional uses.
19) Table:
Table refers to a systematic arrangement of data or information. In this context, tables may be used to summarize research findings and medicinal properties of Argemone mexicana, aiding in the organization and clear presentation of pharmacological data for easier reference.
20) Blood:
Blood is essential for transporting nutrients and oxygen to cells and removing waste. The text discusses how Argemone mexicana extracts impact blood glucose levels, reflecting its potential role in treating metabolic disorders and enhancing therapeutic understanding of diabetes management.
21) Ravi (Ravin):
Ravi is likely a reference to one of the authors of the study or a significant contributor. The mention highlights the collaborative nature of scientific research, showcasing individual contributions within the collective exploration of Argemone mexicana's medicinal benefits.
22) Pain:
Pain is an unpleasant sensory experience often indicating injury or disease. The text discusses analgesic properties of Argemone mexicana, emphasizing its potential as a natural remedy for managing pain and its role in traditional healing practices.
23) Male:
Male refers to the biological sex of organisms that typically produce small gametes. The text mentions male rats used in studies, emphasizing the importance of selecting appropriate animal models in research to ensure accurate understanding of the pharmacological effects of herbal treatments.
24) Nelumbo nucifera:
Nelumbo nucifera, commonly known as the lotus, is a plant often mentioned in herbal medicine. Its inclusion in the text suggests a comparative analysis with Argemone mexicana, highlighting the pharmacological synergies and different therapeutic potentials of traditional plants.
25) Plumbago zeylanica:
Plumbago zeylanica, known for its medicinal properties, is mentioned to emphasize the synergy seen in polyherbal formulations. This highlights traditional practices of combining multiple medicinal plants to enhance therapeutic outcomes than using single herbs.
26) Satyanasi (Satyanashi):
Satyanasi indicates a local name for Argemone mexicana in India. The mention reflects cultural relevance, illustrating the integration of traditional knowledge in recognizing plant species used for therapeutic purposes in Ayurvedic and local healing practices.
27) Evolution:
Evolution refers to the gradual development of organisms over time. In the context of the text, it underscores the historical significance and adaptability of traditional medicinal practices, especially concerning the utilization of plants like Argemone mexicana through generations.
28) Swelling:
Swelling refers to the expansion or enlargement of body parts due to accumulation of fluids. The text mentions swelling in relation to the misconception about Argemone mexicana causing dropsy, emphasizing the need for accurate information regarding its medicinal use and safety.
29) Epidemic:
Epidemic refers to a rapid outbreak of disease affecting many individuals within a community. The text discusses the misconception of Argemone mexicana being linked to dropsy epidemics, stressing the need for clarity in the understanding of plant-based remedies and their true effects.
30) Relative:
Relative generally refers to a connection or comparison between two or more entities. In the context of pharmacological discussion, it may relate to comparing various medicinal plants' efficacies, exploring their synergistic effects, or understanding dosage implications in therapy.
31) Incision:
Incision refers to a surgical cut made in the skin or flesh. The mention of incision suggests its relevance in experimental studies examining wound healing capabilities of Argemone mexicana, showcasing its potential for practical application in surgical recovery.
32) Ashmari (Asmari):
Ashmari, or urinary stones, is a term used in Ayurveda to describe a specific ailment. The text presents Argemone mexicana’s potential in treating ashmani, reinforcing the plant's relevance in traditional medicine for managing urolithiasis-related conditions.
33) Leprosy:
Leprosy is a chronic infectious disease caused by Mycobacterium leprae. The text indicates the historical use of Argemone mexicana for treating leprosy, affirming its significance in traditional South Asian medicine and prompting further modern research.
34) Sakshi (Saksi):
Sakshi is likely a contributor or researcher associated with the studies mentioned in the text. It highlights the collaborative aspect of scientific inquiries, where various researchers contribute to the comprehensive understanding of Argemone mexicana’s pharmacological profile.
35) Aureus:
Aureus refers to a specific group of bacteria, particularly Staphylococcus aureus, known for its pathogenicity. The text discusses Argemone mexicana's ability to combat such bacteria, highlighting its potential as a natural antibacterial agent in addressing infections.
36) Family:
Family denotes a taxonomic category in biological classification. The mention of the Papaveraceae family emphasizes Argemone mexicana's botanical lineage, linking its characteristics, properties, and potential applications within medicinal and pharmaceutical contexts.
37) Cancer:
Cancer is a group of diseases characterized by uncontrolled cell growth. The text discusses the anticancer properties of Argemone mexicana, underscoring the importance of plants in modern oncology and research for novel therapeutic compounds.
38) Silver:
Silver often refers to silver nanoparticles, known for their antimicrobial properties. The text mentions Argemone mexicana's silver nanoparticles, indicating the exploration of modern formulations combining traditional herbal medicine with nanotechnology to enhance therapeutic efficacy.
39) Jvara:
Jvara is an Ayurvedic term for fever. The text notes Argemone mexicana’s traditional usage for symptomatic relief, reinforcing the plant's relevance in managing common ailments and its integration within ancient healing practices.
40) Krimi (Krmi):
Krimi refers to worms or parasites in Ayurveda. The text indicates Argemone mexicana's traditional use against such ailments, highlighting the plant’s relevance in parasitic infections and its place within herbal medicine.
41) Gupta:
Gupta likely refers to a researcher or an author included in the study, emphasizing the collaborative nature of scientific investigations in understanding the therapeutic benefits of Argemone mexicana and validating traditional claims through rigorous research.
42) India:
India is noted for its rich heritage in herbal medicine and practices like Ayurveda. The mention of India highlights the local knowledge surrounding Argemone mexicana, reinforcing its cultural significance and continued research on traditional medicinal plants.
43) Water:
Water is essential for life, and in the context of the text, it suggests hydration in relation to treatments. The effects of Argemone mexicana extracts with or without water may reflect on its effectiveness in different forms of herbal preparations.
44) Chang:
Chang likely refers to a researcher or author associated with the studies cited regarding Argemone mexicana and its anti-HIV potential. This shows the importance of collaboration in research and the ongoing exploration of herbal pharmacology.
45) Edema (Oedema):
Edema refers to swelling caused by fluid accumulation in tissues. The text mentions the relationship of Argemone mexicana with conditions like dropsy and edema, suggesting its relevance in addressing these swelling-related ailments traditionally.
46) Fever:
Fever is a common response to infection, often treated with herbal remedies. The text highlights the traditional usage of Argemone mexicana in managing fever symptoms, reinforcing its therapeutic potential within folk medicine.
47) Visha (Visa):
Visha refers to poisoning or toxic effects in Ayurveda. The text mentions Argemone mexicana's use in treating visha, emphasizing its historical relevance in managing symptoms associated with toxicities and reinforcing its role in traditional healing.
48) Kasa (Kasha):
Kasa refers to cough, a common respiratory condition. The text discusses how Argemone mexicana has been traditionally used to alleviate cough symptoms, emphasizing its role as a natural remedy in traditional Ayurvedic medicine.
49) Food:
Food is fundamental for nutrition and energy. In the context of the text, it highlights the importance of understanding the dietary roles of medicinal plants like Argemone mexicana, particularly in their traditional usage alongside conventional food systems.
50) Sahu:
Sahu likely refers to a researcher or contributor involved in studies related to Argemone mexicana, showcasing the collaborative effort among scientists in exploring its diverse medicinal properties and contributing to a broader understanding of its pharmacological implications.
51) Sign:
Sign refers to an indication or evidence. In the text, signs may relate to the observable benefits or outcomes of using Argemone mexicana in studies, validating its efficacy in treating various ailments through clear results.
52) Line:
Line typically indicates a sequence or category. In this context, it may refer to taxonomic classification that positions Argemone mexicana within specific groups, aiding in the understanding of its biological and pharmacological classifications.
53) Oil:
Oils refer to lipid substances often used in herbal formulations. The text discusses the relationship between edible oils and the toxicity associated with Argemone mexicana, reinforcing the significance of understanding proper usage and the formulations in which these plants are utilized.
Other Science Concepts:
Discover the significance of concepts within the article: �Therapeutic potential of Argemone maxicana in Ayurveda and research�. Further sources in the context of Science might help you critically compare this page with similair documents:
Traditional medicine, Wound healing, Peptic ulcer, Antioxidant activity, Anti-inflammatory, Analgesic activity, Research activities, Antimicrobial activity, Hepatoprotective activity, Antidiabetic activity, Neuropharmacological activity, Bioactive compound, Antiulcer activity, Gram-positive and Gram-negative, Analgesic properties, Sedative effect, Antiurolithiatic activity, Ureterolithiasis, Polyphenol compound.
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