Can MTA be: Miracle trioxide aggregate?
Journal name: Journal of Indian Society of Periodontology
Original article title: Can MTA be: Miracle trioxide aggregate?
The Journal of Indian Society of Periodontology (JISP) publishes original scientific articles on periodontology (the study of supporting structures of teeth) and oral implantology. It is a bimonthly open-access journal with special issues for specific occasions.
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Reshma M Naik, Pushpa S Pudakalkatti, Sanjeevini A Hattarki
Journal of Indian Society of Periodontology:
(A bimonthly open-access journal)
Full text available for: Can MTA be: Miracle trioxide aggregate?
Year: 2014 | Doi: 10.4103/0972-124X.128190
Copyright (license): CC BY-NC-SA
Summary of article contents:
Introduction
Mineral trioxide aggregate (MTA) has been widely recognized in the dental community for over a decade as a preferred material for endodontic procedures. Its significance lies in the interplay between dental pulp and periodontal tissues, leading to the understanding that diseases affecting one can influence the health of the other, with pulpal and periodontal issues contributing to over 50% of tooth loss. This interrelationship advocates for a collaborative approach between endodontists and periodontists, highlighting MTA’s potential in not only endodontics but also in periodontal treatments, owing to its unique ability to promote cementum overgrowth and potentially facilitate tissue regeneration.
MTA and Periodontal Regeneration
One of the primary advantages of MTA is its application in periodontal procedures. MTA is recognized as a bioactive material that supports the growth and differentiation of cementoblasts and other hard tissue-producing cells. Studies have shown that MTA encourages cementoblast attachment, proliferation, and mineralized matrix production, establishing it as a cementoconductive material. Moreover, MTA demonstrates osteogenic properties, as evidenced by its positive effects on osteoblasts, leading to increased production of bone-related proteins. The material facilitates an environment conducive to healing, releasing calcium ions that enhance cell attachment and modulate the activity of cytokines. Despite the encouraging research findings, there remains a necessity for clinical studies to validate the benefits and performance of MTA in humans.
Conclusion
In conclusion, MTA emerges as a pivotal material in treating combined endodontic and periodontal lesions, offering significant biologic responses such as hydroxyapatite formation upon contact with physiological solutions. Its multifaceted potential in both endodontics and periodontics underscores its classification as a "miracle trioxide aggregate." However, while existing studies hint at its efficacy in enhancing periodontal regeneration and healing, future longitudinal research is essential to substantiate its clinical applications. Until more rigorous and well-controlled clinical trials are conducted, the widespread adoption of MTA in various dental disciplines should be approached with caution, considering the current reliance on animal and in vitro studies for much of the supporting data.
FAQ section (important questions/answers):
What is Mineral Trioxide Aggregate (MTA) used for in dentistry?
MTA is commonly used in endodontics for procedures like root-end filling, pulp capping, and apexification. It is also useful for periodontal tissue regeneration due to its biocompatibility and ability to promote cementum overgrowth.
What are the benefits of using MTA in periodontal treatments?
MTA enhances periodontal repair by facilitating cementogenesis, promoting cell attachment and growth, and creating an antibacterial environment. It has shown effective results in regenerating periodontal tissues, making it a valuable material in periodontal procedures.
What are the main drawbacks of Mineral Trioxide Aggregate?
The drawbacks of MTA include potential discoloration, long setting time, high cost, and difficulty in removal after curing. These factors may limit its use in certain clinical situations despite its benefits.
How does MTA promote healing in dental procedures?
MTA releases calcium ions, enhances cell attachment, modulates cytokine production, and encourages differentiation of hard tissue-forming cells. Its high pH also creates an antibacterial environment, promoting healing and regeneration.
Is there sufficient clinical evidence supporting MTA's effectiveness?
While there are numerous in vitro and animal studies supporting MTA's benefits, further longitudinal studies in humans are necessary. Current evidence is not sufficient for systematic and meta-analytical reviews of its clinical applications.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Can MTA be: Miracle trioxide aggregate?�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Repair:
Repair refers to the processes involved in restoring the structure and function of damaged biological tissues. In the context of dentistry and periodontal treatment, repair is crucial for recovering health in the periodontium. Materials like Mineral Trioxide Aggregate (MTA) are designed to facilitate repair by promoting regeneration and healing.
2) Mineral:
Minerals are naturally occurring inorganic substances essential for various biological functions. In dentistry, minerals like calcium and phosphate are significant for tooth structure and health. MTA, a mineral-based material, aids in cementogenesis and periodontal regeneration, highlighting the importance of minerals in restorative dental treatments.
3) Antibiotic (Antibacterial):
Antibacterial refers to the property of a substance to inhibit the growth or kill bacteria. In dental materials such as MTA, antibacterial properties are important to prevent infections during procedures. The ability of MTA to create an alkaline environment that impedes bacterial growth enhances its usability in endodontic treatments.
4) Surface:
Surface refers to the outermost layer of a material, which interacts with bodily tissues in dental applications. The surface properties of materials like MTA affect cell attachment, proliferation, and tissue regeneration. A suitable surface promotes biocompatibility, necessary for the successful integration of restorative materials in the oral cavity.
5) Disease:
Disease pertains to pathological conditions affecting the body, commonly resulting in dysfunction or impaired health. In dentistry, diseases like pulpal and periodontal infections elevate the need for treatment. Knowledge of disease pathology aids in developing effective procedures and materials, such as MTA, that facilitate healing and tissue regeneration.
6) Species:
Species refers to distinct groups of organisms sharing common characteristics, particularly in biological contexts. Understanding the various bacterial species that inhabit the oral cavity is crucial for developing antibacterial treatments. MTA's effectiveness can vary across species, necessitating thorough research to ascertain its activity against specific pathogens.
7) Filling (Filled):
Filling involves the placement of a dental material to restore the structure and function of a tooth affected by decay or trauma. MTA serves as a filling material in endodontics and periodontics, allowing for effective sealing of root canals and promoting biological healing. Its properties facilitate material retention and tissue regeneration.
8) Animal:
Animal studies are essential for understanding the biological interactions of dental materials before human application. Research using animal models assists in assessing the efficacy and safety of materials like MTA. Results derived from these studies guide clinical practices and inform further investigations into human periodontal and endodontic treatments.
9) Powder:
Powder refers to a finely ground substance, vital in the formulation of dental materials. MTA, composed of powder, sets in the presence of moisture. Understanding the powder characteristics, such as particle size and composition, aids in evaluating its handling properties and overall performance in various clinical applications.
10) Field:
Field denotes a specific area of study or professional practice. In dentistry, the fields of endodontics and periodontics often intersect when dealing with conditions affecting both pulp and periodontal tissues. MTA has applications across multiple fields, contributing significantly to interdisciplinarity in dental treatment approaches.
11) Performance:
Performance in dental materials refers to their effectiveness and reliability in clinical applications. MTA demonstrates favorable performance in sealing root canals, promoting regeneration, and providing biocompatibility. Evaluating material performance is crucial for ensuring successful treatment outcomes and guiding practitioners in selecting appropriate materials for specific dental issues.
12) Surrounding:
Surrounding refers to the adjacent tissues or structures that interact with a material or an affected area. In dentistry, understanding the surrounding periodontal and pulpal tissue dynamics is crucial for effective treatments. MTA, for instance, interacts with surrounding tissues to facilitate healing and regeneration, reflecting its importance in various procedures.
13) Science (Scientific):
Scientific pertains to systematic knowledge acquisition based on observation and experimentation. In dentistry, scientific research informs the development of materials like MTA, evaluating their biocompatibility, effectiveness, and safety. Scientific evidence supports clinical practices, ensuring treatments align with best practices established through rigorous investigation and peer-reviewed studies.
14) Activity:
Activity refers to a material's biological response, specifically its functional properties in clinical settings. MTA's activity includes promoting cell growth, facilitating mineralization, and exhibiting antibacterial effects. Understanding such activities is essential for evaluating its effectiveness in procedures requiring tissue regeneration or repair in endodontics and periodontics.
15) Quality:
Quality describes the standard or degree of excellence of a material or product. In dental materials, the quality of MTA dictates its effectiveness and suitability for various clinical applications. High-quality materials ensure biocompatibility, appropriate handling characteristics, and reliable performance, all pertinent to successful dental treatment outcomes.
16) Aureus:
Aureus, often referring to Staphylococcus aureus, is a type of bacteria significant in clinical studies due to its pathogenicity. Understanding the interaction between materials like MTA and Aureus is vital for assessing antibacterial properties and the material's effectiveness in preventing infections during dental procedures involving tooth repair.
17) Water:
Water is essential for hydration and health, especially in biological processes. In dental applications, water plays a crucial role in setting materials like MTA, which requires moisture to gain optimal properties. The interaction of dental materials with water dictates their handling characteristics and overall performance in clinical use.
18) Table:
Table, in academic contexts, refers to a systematic arrangement of information. In scientific literature, tables often present data and findings related to studies on materials like MTA. Well-organized tables facilitate knowledge dissemination, enabling practitioners to quickly review and compare relevant information vital for clinical decision-making.
19) Blood:
Blood is vital in maintaining physiological functions and healing processes in the body. It plays a role in wound healing and tissue repair. The interaction of materials like MTA with blood during dental procedures can influence healing outcomes, emphasizing the importance of blood characteristics in evaluating material effectiveness and safety.
20) Food:
Food is essential for nutrition and health. In dental contexts, it can influence oral health and the development of diseases. The presence of certain foods can impact the microbiome and the efficacy of dental materials. Knowledge of dietary influences informs treatment strategies, particularly in periodontal management.
21) Pose:
Pose refers to a challenge or dilemma that arises within a specific context. In dentistry, complex cases, such as concurrent periodontal and pulpal disease, can pose significant treatment challenges. Understanding these complexities guides practitioners in selecting appropriate materials and strategies, like using MTA, to tackle the inherent challenges effectively.
22) Rich (Rch):
Rich often describes an abundance or high concentration of specific nutrients or materials. In biological contexts, a rich environment may support cellular activity and growth. In dentistry, using a rich nutrient medium can enhance the regenerative capacity of materials like MTA, promoting effective healing and tissue repair.
23) Drug:
Drug refers to a chemical substance utilized for therapeutic purposes, impacting physiological functions. In dentistry, the concept of drug extends to materials like MTA, which possesses properties that can influence biological responses similar to pharmaceuticals. Understanding the drug-like behavior of dental materials informs their use in treatment protocols.
Other Science Concepts:
Discover the significance of concepts within the article: �Can MTA be: Miracle trioxide aggregate?�. Further sources in the context of Science might help you critically compare this page with similair documents:
Interdisciplinary approach, Clinical studies, Periodontal health, Biocompatibility, Endodontic therapy, Clinical application, Biological response, Clinical performance, Periodontal regeneration, Cumulative evidence, Periodontal tissue, Mineral trioxide aggregate, Tooth mortality, Hard tissue formation.