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A clinical study to evaluate the efficacy of manjisthadi taila in vrana ropana

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Journal name: Ayushdhara
Original article title: A clinical study to evaluate the efficacy of manjisthadi taila in vrana ropana
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Author(s):

Gupta Pooja
Assistant professor, Department of PG Studies in Shalyatantra, Jammu Institute of Ayurveda & Research, Nardini (Raipur), Jammu
*Gupta Sudesh
Associate Professor, Department of PG Studies in Shalyatantra, Jammu Institute of Ayurveda & Research, Nardini (Raipur), Jammu
Gupta Bhawana
Medical officer, National Rural Health Mission, Ministry of Health and Family Welfare, Govt of India, PHC-Siot, District-Rajouri, J&K
Madhubala Bhagat
PG Scholar, Department of PG Studies in Shalyatantra, Jammu Institute of Ayurveda & Research, Nardini (Raipur), Jammu
Singh Manpreet
Singh Bhopinder
PG Scholar, Department of PG Studies in Shalyatantra, Jammu Institute of Ayurveda & Research, Nardini (Raipur), Jammu


Ayushdhara:

(A peer-reviewed, bi-monthly open-access journal)

Full text available for: A clinical study to evaluate the efficacy of manjisthadi taila in vrana ropana

Year: 2016

Copyright (license): CC BY-NC-SA 4.0


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Summary of article contents:

Introduction

Wound healing is a multifaceted process involving several phases, including haemostasis, inflammation, granulation, and maturation. The efficiency of wound management often necessitates the use of multiple therapeutic agents, as achieving complete healing with a single drug can be challenging. This study focuses on the efficacy of Manjishtadi Taila, a traditional Ayurvedic formulation, in promoting wound healing or "Vrana Ropana." The trial evaluated its effectiveness against standard treatment with Povidone-Iodine dressings in various cases, such as surgical wounds and excisions.

Composition and Properties of Manjishtadi Taila

Manjishtadi Taila is composed of several medicinal herbs known for their healing properties, including Manjistha, Haridra, Bharangi, and others. This formulation is unique due to its dual functionality: it acts as both a cleansing agent (Vrana Shodhana) and a healing promoter (Vrana Ropana). The drug's composition not only facilitates the removal of impurities from the wound but also promotes epithelialization and tissue regeneration. Innovative procedures described in Ayurvedic texts guided the preparation of this oil, highlighting the importance of traditional practices blended with modern medicinal understanding.

Clinical Efficacy and Observations

The clinical study involved 40 patients divided into two groups: one treated with Manjishtadi Taila and the other with Povidone-Iodine. Key clinical indicators such as pain, swelling, tenderness, discharge, color, odor, and granulation tissue were assessed before and after treatment. Results indicated significant improvement in the group receiving Manjishtadi Taila, showcasing reductions in pain, swelling, and discharge, alongside enhancements in granulation tissue. The average healing duration was notably shorter in the Manjishtadi Taila group compared to the control group, underscoring its potential as an effective treatment for wound management.

Conclusion

The findings from this clinical study suggest that Manjishtadi Taila is highly effective in enhancing the process of wound healing, exhibiting notable results without adverse effects. Patients treated with Manjishtadi Taila experienced quicker recovery times and satisfactory cosmetic results compared to those treated with Povidone-Iodine. This study reinforces the therapeutic potential of traditional Ayurvedic formulations in modern medical practices. Therefore, Manjishtadi Taila emerges as a promising option for clinicians seeking effective wound care treatments.

FAQ section (important questions/answers):

What is the objective of the clinical study on Manjisthadi Taila?

The objective of the study is to evaluate the efficacy of Manjisthadi Taila in promoting wound healing (Vrana Ropana) and to compare its effects with Povidone-Iodine dressing in managing various types of wounds.

What are the main ingredients of Manjisthadi Taila?

Manjisthadi Taila contains several herbal ingredients including Tila Taila, Manjistha, Haridra, Bharangi, and others, which are known for their cleansing (Shodhana) and healing (Ropana) properties in Ayurvedic medicine.

How was the efficacy of Manjisthadi Taila measured in the study?

Efficacy was measured using both subjective and objective criteria, including pain, swelling, discharge, granulation tissue formation, and overall wound healing progress. Statistical analyses were performed to compare outcomes between the trial group and the control group.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “A clinical study to evaluate the efficacy of manjisthadi taila in vrana ropana�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Vrana:
Vrana refers to a wound, which is the focus of the study. The study evaluates the efficacy of Manjisthadi Taila in Vrana Ropana or wound healing. Proper management of Vrana involves stages like Shodhana (cleansing) and Ropana (healing).

2) Taila:
Taila means oil, used for therapeutic purposes in Ayurveda. In the context of the study, Manjisthadi Taila is an oil prepared from various herbal ingredients and applied topically to wounds to evaluate its healing effects.

3) Ropana:
Ropana refers to the healing process. The study aims to evaluate the efficacy of Manjisthadi Taila in Vrana Ropana, focusing on the stages of wound healing and how the herbal oil facilitates this process.

4) Drug:
In this context, the term 'drug' refers to Manjisthadi Taila, a medicinal preparation used in the study to manage wounds. It is composed of various Ayurvedic herbs with Shodhana and Ropana properties.

5) Manjishthadi (Manjisthadi):
Manjisthadi refers to the herbal formulation named after its primary ingredient, Manjistha. The oil, Manjisthadi Taila, is studied for its effectiveness in healing wounds or Vrana Ropana.

6) Pain:
Pain is one of the clinical features assessed in the study to evaluate the effectiveness of Manjisthadi Taila. The oil reportedly reduces pain, among other symptoms, in the trial group.

7) Shodhana (Sodhana):
Shodhana refers to the cleansing process essential in the initial phase of wound healing. Manjisthadi Taila possesses Shodhana properties, making it effective in preparing the wound for Ropana or healing.

8) Inflammation:
Inflammation is a significant factor in wound healing, often causing pain and delaying the process. Manjisthadi Taila is assessed for its anti-inflammatory properties, contributing to effective Vrana Ropana.

9) Vranaropana (Vrana-ropana):
Vranaropana is a term for wound healing in Ayurveda. The study focuses on evaluating the efficacy of Manjisthadi Taila in Vranaropana, assessing various clinical features like pain, swelling, discharge, and granulation tissue.

10) Ayurveda (Ayus-veda):
Ayurveda is the ancient Indian system of medicine from which the principles and treatments explored in this study are derived. The study uses Ayurvedic formulations like Manjisthadi Taila to assess wound healing.

11) Guna:
In Ayurveda, Guna refers to the qualities or properties of a substance. The study explores the Gunas of Manjisthadi Taila, which include cooling (Sheeta), anti-inflammatory, and healing properties important for Vrana Ropana.

12) Swelling:
Swelling is one of the clinical symptoms assessed in the study to measure the effectiveness of Manjisthadi Taila. The oil helps in reducing swelling, which is a component of inflammation in wound healing.

13) Gupta:
Gupta refers to the authors and contributors of the study, including Dr. Pooja Gupta, Dr. Sudesh Gupta, and others. They conducted the clinical research on the effectiveness of Manjisthadi Taila in wound healing.

14) Dhatu:
Dhatu refers to the fundamental tissues of the body in Ayurveda. The study focuses on local Dhatu Dushti (tissue vitiation) in wounds and how Manjisthadi Taila aids in cleansing and healing these tissues.

15) Blood:
Blood is referred to as Rakta in Ayurveda, and its purification (Rakta Shodhana) is crucial in wound healing. Manjisthadi Taila contains ingredients that are said to purify the blood, thus aiding in Vrana Ropana.

16) Rasa (Rasha):
Rasa in Ayurveda refers to taste, which influences the properties and actions of a drug. The study mentions various Rasas like Madhur (sweet) and Kashaya (astringent) that contribute to the healing properties of Manjisthadi Taila.

17) Manjishtha (Manjistha, Mamjishtha):
[see source text or glossary: Manjishtha]

18) Vranashodhana (Vranasodhana, Vrana-shodhana):
[see source text or glossary: Vranashodhana]

19) Tilataila (Tila-taila):
Tila-taila refers to sesame oil, used as the base oil in the preparation of Manjisthadi Taila. It is known for its soothing and penetrative properties in Ayurvedic medicine.

20) Haritaki:
Haritaki is one of the ingredients in Manjisthadi Taila, known for its cleansing and healing properties. It contributes to both Vrana Shodhana and Ropana in the formulation.

21) Bharangi (Bharamgi):
Bharangi is an ingredient in Manjisthadi Taila, contributing to its anti-inflammatory and healing properties. It aids in reducing swelling and enhancing the Vrana Ropana process.

22) Haridra:
Haridra, known as turmeric, is included in Manjisthadi Taila for its potent anti-inflammatory, antimicrobial, and wound-healing properties, essential for both Vrana Shodhana and Ropana.

23) Tila:
Tila refers to sesame, the base oil (Tila Taila) used in the preparation of Manjisthadi Taila. It enhances the formulation's ability to penetrate the skin and deliver the therapeutic effects of the herbs.

24) Sushruta-samhita (Susruta-samhita):
The Sushruta Samhita is an ancient Ayurvedic text attributed to Sushruta, the father of surgery. It provides comprehensive guidelines on wound management, including the use of Manjisthadi Taila for Vrana Ropana.

25) Knowledge:
Knowledge in the study refers to understanding the principles of wound healing, incorporating both modern medical insights and ancient Ayurvedic wisdom as detailed in texts like the Sushruta Samhita.

26) Samhita:
Samhita refers to ancient Ayurvedic texts. The study draws from Sushruta Samhita, a foundational text detailing various treatments, including those for wound management like Manjisthadi Taila.

27) Vidanga (Vidamga):
Vidanga is one of the herbal ingredients used in Manjisthadi Taila, known for its antimicrobial and healing properties, contributing to both Vrana Shodhana and Ropana.

28) Kashaya (Kasaya):
Kashaya or astringent taste is a property of several ingredients in Manjisthadi Taila. This taste aids in wound healing by providing Stambhana (contraction), Shoshana (drying), and Rakta Shodhana (blood-purifying) effects.

29) Shuddha (Suddha):
Shuddha refers to the purified state of a wound after Shodhana (cleansing). Manjisthadi Taila is used in the study to achieve and maintain Shuddha Vrana, ensuring effective Vrana Ropana.

30) Shotha (Sotha):
Shotha means inflammation. The study evaluates Manjisthadi Taila for its effectiveness in reducing Shotha, which is essential for the healing process of Vrana or wounds.

31) Lodhra:
Lodhra is one of the ingredients in Manjisthadi Taila, known for its anti-inflammatory and healing properties. It contributes to both Shodhana and Ropana of Vrana.

32) Karma (Karman):
Karma in Ayurveda refers to the action or effect of a drug. The study explores the Karma of Manjisthadi Taila, focusing on its Shodhana (cleansing) and Ropana (healing) actions on wounds.

33) Rakta:
Rakta refers to blood in Ayurveda. The study emphasizes the importance of Rakta Shodhana (blood purification) in wound healing, a property attributed to Manjisthadi Taila.

34) India:
India is the country where the study was conducted, specifically at the Jammu Institute of Ayurveda & Research. Ayurveda, the basis for the study, originates and is widely practiced in India.

35) Pooja:
Pooja refers to Dr. Pooja Gupta, one of the lead researchers involved in the clinical study evaluating the efficacy of Manjisthadi Taila in wound healing or Vrana Ropana.

36) Paka:
[see source text or glossary: Paka]

37) Shalyatantra (Salyatantra, Shalya-tantra, Shalyatamtra):
Shalyatantra, also known as Shalya-tantra, is the branch of Ayurveda specializing in surgery. The department conducted the clinical study on Manjisthadi Taila for wound healing.

38) Yashtimadhu (Yastimadhu, Yashti-madhu):
Yashtimadhu, also known as Licorice, is one of the ingredients in Manjisthadi Taila. It is known for its anti-inflammatory, antimicrobial, and wound-healing properties, aiding in both Shodhana and Ropana.

39) Shoshana (Sosana):
Shoshana refers to drying. In the context of the study, the Shoshana property of Manjisthadi Taila helps in drying the wound secretions, thus aiding in the healing process or Vrana Ropana.

40) Chedana:
Chedana refers to excision or cutting. The term is used in the context of wound management to describe the removal of necrotic tissue. Some ingredients in Manjisthadi Taila possess Chedana properties aiding wound management.

41) Lekhana:
Lekhana refers to scraping or cleansing properties. Manjisthadi Taila contains herbs with Lekhana properties, helping to remove dead tissue and debris from the wound for effective Shodhana and Ropana.

42) Visada (Vishada, Visha-da):
Vishada refers to a property that aids in cleansing and drying wounds. In the context of the study, Manjisthadi Taila has Vishada properties, which help in Shodhana and preparing the wound for Ropana.

43) Tantra (Tamtra, Tantrism):
[see source text or glossary: Tantra]

44) Shalya (Salya):
[see source text or glossary: Shalya]

45) Repair:
[see source text or glossary: Repair]

46) Sharman (Sarma, Sharma, Sarman):
Sharma refers to Dr. Roop Lal Sharma, one of the people acknowledged for their support in conducting the study at the Jammu Institute of Ayurveda & Research.

47) Kalka:
[see source text or glossary: Kalka]

48) Tikta:
[see source text or glossary: Tikta]

49) Burning sensation:
[see source text or glossary: Burning sensation]

50) Rubia cordifolia:
[see source text or glossary: Rubia cordifolia]

51) Dhatuvardhana (Dhatu-vardhana):
[see source text or glossary: Dhatu-vardhana]

52) Ksharasutra (Ksarasutra, Kshara-sutra):
[see source text or glossary: Ksharasutra]

53) Tuberculosis:
[see source text or glossary: Tuberculosis]

54) Purification:
[see source text or glossary: Purification]

55) Samshodhana (Samsodhana):
[see source text or glossary: Samshodhana]

56) Raktadhatu (Rakta-dhatu):
[see source text or glossary: Raktadhatu]

57) Shothahara (Sothahara, Shotha-hara):
[see source text or glossary: Shothahara]

58) Discussion:
The discussion section of the study elaborates on the phases of wound healing, the properties of Manjisthadi Taila, and its effectiveness compared to conventional treatments, emphasizing the study's findings.

59) Krimighna (Krmighna, Krimi-ghna):
[see source text or glossary: Krimighna]

60) Rasakriya (Rasa-kriya):
[see source text or glossary: Rasakriya]

61) Prasadana:
[see source text or glossary: Prasadana]

62) Lakshana (Laksana):
[see source text or glossary: Lakshana]

63) Raktagni (Rakta-agni):
[see source text or glossary: Raktagni]

64) Vatahara (Vata-ahara):
[see source text or glossary: Vatahara]

65) Medicine:
[see source text or glossary: Medicine]

66) Tinduka (Timduka):
[see source text or glossary: Tinduka]

67) Snigdha:
[see source text or glossary: Snigdha]

68) Avastha:
[see source text or glossary: Avastha]

69) Rasagni (Rasa-agni):
[see source text or glossary: Rasagni]

70) Prinana:
[see source text or glossary: Prinana]

71) Samana (Shamana):
[see source text or glossary: Shamana]

72) Disease:
[see source text or glossary: Disease]

73) Dravya:
[see source text or glossary: Dravya]

74) Kshara (Ksara):
[see source text or glossary: Kshara]

75) Varṇya (Varnya):
[see source text or glossary: Varnya]

[Note: The above list is limited to 75. Total glossary definitions available: 89]

Other Science Concepts:

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Discover the significance of concepts within the article: �A clinical study to evaluate the efficacy of manjisthadi taila in vrana ropana�. Further sources in the context of Science might help you critically compare this page with similair documents:

Vranaropana, Healing activities, Healing properties, Wound healing, Statistical analysis, Control group, Granulation tissue, Clinical study, Ethical committee approval, Ayurvedic text, Subjective Criteria, Objective Criteria, Antimicrobial action, Trial Group, Patients aged, Povidone Iodine, Manjishtadi Taila, Shudha Vrana, Epithelial layer, Inflammation phase, Active chemical constituent.

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