Randomized placebo-controlled trial of Mustadi Ghanavati in hyperlipidemia
Journal name: AYU (Journal of Research in Ayurveda)
Original article title: Randomized placebo-controlled trial of Mustadi Ghanavati in hyperlipidemia
AYU is an internationally recognized quarterly journal dedicated to advancing research in Ayurveda. The journal covers a wide range of topics, including clinical and pharmacological research in Ayurveda's eight branches, herbal remedies, phytochemistry, and ethnomedicine.
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Manjiri Arun Nadkarni
S. N. Vyas
M. S. Baghel
B. Ravishankar
AYU (Journal of Research in Ayurveda):
(An International Quarterly Journal of Research in Ayurveda)
Full text available for: Randomized placebo-controlled trial of Mustadi Ghanavati in hyperlipidemia
Year: 2010 | Doi: 10.4103/0974-8520.77150
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Hyperlipidemia is one of the major lifestyle disorders. Its role has been appreciated in the manifestation of serious diseases like ischemic heart disease, diabetes, stroke etc. These lifestyle diseases are a result of lifestyle factors such as overnutrition etc., which have been referred to as the Santarpanjanya Vyadhis in the classical texts. Mustadi Ghanavti is a modified form of the classical formulation Mustadi Kwath that has been advocated by Acharya Charaka for the management of Santarpanjanya Vikaras. This placebo-controlled randomized trial of Mustadi Ghanavati was carried out on 61 patients suffering from hyperlipidemia; of the 61 patients, 50 completed the entire course of treatment. The results of the study revealed that Mustadi Ghanavati decreased serum cholesterol by 22.4%, serum triglycerides by 19.6%, serum LDL by 18.2%, and serum VLDL by 4.2%; serum HDL increased by 5.6%. Thus Mustadi Ghanavati was able to effect a total improvement of 58.8% in the lipid profile. It brought about mild improvement in 42.86% of patients and moderate improvement in 14.28% of patients. Mustadi Ghanavati was also found to have a significant effect on other subjective as well as objective parameters considered for the study. Keywords: Hyperlipidemia, Mustadi Ghanavati, placebo-controlled trial
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