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Analgesic effect of Lepidium sativum Linn. (Chandrashura) in experimental animals

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Journal name: AYU (Journal of Research in Ayurveda)
Original article title: Analgesic effect of Lepidium sativum Linn. (Chandrashura) in experimental animals
AYU is an internationally recognized quarterly journal dedicated to advancing research in Ayurveda. The journal covers a wide range of topics, including clinical and pharmacological research in Ayurveda's eight branches, herbal remedies, phytochemistry, and ethnomedicine.

Original source:

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Author(s):

Nita D. Raval
B. Ravishankar


AYU (Journal of Research in Ayurveda):

(An International Quarterly Journal of Research in Ayurveda)

Full text available for: Analgesic effect of Lepidium sativum Linn. (Chandrashura) in experimental animals

Year: 2010 | Doi: 10.4103/0974-8520.77163

Copyright (license): CC BY-NC-SA 4.0


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Summary of article contents:

Lepidium sativum Linn, which is known as “Aselio� locally, is frequently used by the villagers for the treatment of Sandhivata (osteoarthritis), with good therapeutic relief. Here, we have to observe the analgesic activity of the seed of Lepidium sativum Linn in albino rats and Swiss albino mice with different parameters. The analgesic study was performed with acetic acid-induced writhing response in mice, formaldehyde-induced paw licking response in rats and tail flick response in mice. Experiments were carried out in two groups � therapeutic dose group and double dose group � with comparison with the control group. In the acetic acid-induced writhing syndrome, latency of onset was highly significantly increased in the therapeutic dose group and significant increase was found in the double dose group. In the formaldehyde-induced paw licking response, the test drug produced significant inhibition of neurogenic pain in the double dose group and significant inhibition of inflammatory pain in the therapeutic dose group. In the tail flick response, the test drug produced a mild to moderate effect in the therapeutic dose group and also in the double dose group. Keywords: Analgesic, paw licking response, tail flick, writhing response, Lepidium sativum Linn

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Discover the significance of concepts within the article: �Analgesic effect of Lepidium sativum Linn. (Chandrashura) in experimental animals�. Further sources in the context of Science might help you critically compare this page with similair documents:

Statistical analysis, Control group, Analgesic activity, Sandhivata osteoarthritis, Lepidium sativum Linn, Swiss albino mice, Acetic acid-induced writhing response, Tail flick response, Double dose group, Pain threshold, Inflammatory pain, Neurogenic pain, Albino rat, Prostaglandin.

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