Phytochemical and antimicrobial study of Oroxylum indicum
Journal name: Ancient Science of Life
Original article title: Phytochemical and antimicrobial study of Oroxylum indicum
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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L.G. Radhika, C V Meena, Sujha Peter, K S Rajesh, M P Rosamma
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Phytochemical and antimicrobial study of Oroxylum indicum
Year: 2011
Copyright (license): CC BY-NC-SA
Summary of article contents:
Introduction
Oroxylum indicum, a plant prominently featured in Ayurvedic medicine, is included among the group of ten drugs known as Dasamoola. This study aims to investigate the phytochemical and antimicrobial properties of the plant’s root and stem, especially since the root, which is the officinal part, is often adulterated with the stem. By performing thorough analysis through physico-chemical parameters, Thin Layer Chromatography (TLC), and antimicrobial tests, the researchers seek to clarify the distinct chemical profiles and therapeutic applications of both parts of the plant.
Distinct Chemical Properties
The study revealed significant differences between the phytochemical compositions of the root and stem of Oroxylum indicum. Various fractions containing lipids, phenols, and alkaloids were isolated and subjected to TLC analysis, showcasing distinct Rf values that distinguished the two parts of the plant. The bacterial assay demonstrated that the stem extract exhibited greater antibacterial activity, especially against pathogens related to diarrhea, compared to the root extract. These findings not only validate traditional Ayurvedic classifications about each part's differing therapeutic actions but also underscore the importance of distinguishing between the two to ensure proper usage in medicinal formulations.
Conclusion
The research highlights the valuable insights gained into the medicinal properties of Oroxylum indicum through modern analytical techniques. The findings reaffirm the need for stringent quality control to prevent adulteration of the root with the stem, as they demonstrate that both parts possess different chemical constituents and varying degrees of antimicrobial efficacy. Understanding these distinctions provides a foundation for the safe and effective application of Oroxylum indicum in Ayurvedic medicine, potentially leading to improved therapeutic outcomes and preservation of traditional knowledge in herbal pharmacology.
FAQ section (important questions/answers):
What is the significance of Oroxylum indicum in Ayurveda?
Oroxylum indicum, commonly known as Syonaka, is included in Dasamoola, a group of ten drugs in Ayurveda. The root is primarily utilized for various therapeutic properties, while the stem is mentioned for specific uses, particularly as an anti-diarrheal.
What were the methods used for the antibacterial activity study?
The antibacterial activity of Oroxylum indicum's root and stem extracts was assessed using the agar well diffusion method on Mueller Hinton agar. Alcoholic extracts were tested against multiple bacterial strains to measure the inhibition zones.
How were the physico-chemical parameters of the plant assessed?
The physico-chemical parameters of both the root and stem were determined following guidelines from the Ayurvedic Pharmacopoeia of India. Various extraction methods were employed to identify and compare the chemical constituents present in each part.
What were the findings regarding the antibacterial properties of the extracts?
The study found that the stem extract exhibited stronger antibacterial activity against bacteria like S.aureus and Klebsiella, while the root extract showed less effectiveness. This suggests differences in bioactive components between the stem and root.
Other Science Concepts:
Discover the significance of concepts within the article: �Phytochemical and antimicrobial study of Oroxylum indicum�. Further sources in the context of Science might help you critically compare this page with similair documents:
Oroxylum indicum, Therapeutic action, Medicinal value, Antibacterial activity, Physico-chemical parameters, High performance thin layer chromatography, Thin Layer Chromatography, Ayurvedic classical literature, Ayurvedic Pharmacopoeia of India, Agar well diffusion method, Extractive value, Adulteration and substitution, Chemical constituent, Bioactive component.