Antimicrobial activity of root extracts of dalbergia spinosa roxb
Journal name: Ancient Science of Life
Original article title: Antimicrobial activity of root extracts of dalbergia spinosa roxb
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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R. Senthamarai, G. Umadevi, K.P.Jai Ganesh
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Antimicrobial activity of root extracts of dalbergia spinosa roxb
Year: 2003
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
Dalbergia spinosa Roxb., a large shrub known for its climbing tendency, is found along the coastal areas of the Peninsula and Bengal. Commonly referred to as Jantarikanta and Nechitan cheddi in Tamil, this plant is utilized for various medicinal purposes, including the treatment of fever, pain, skin infections, and urinary tract infections. Previous studies have identified compounds such as dalspinin and dalspinosin within the plant. Given its significant traditional use in herbal medicine, the study aimed to evaluate the antimicrobial activity of the root extracts of Dalbergia spinosa.
Antimicrobial Activity Investigation
The research focused on the antimicrobial properties of different extracts of Dalbergia spinosa's roots, specifically examining benzene, alcoholic, and aqueous extracts. The study employed the cup plate method to test the effectiveness of these extracts against various microorganisms, including gram-positive bacteria such as Staphylococcus aureus and gram-negative bacteria like Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli, as well as the fungus Candida albicans. The results indicated that both the benzene and alcoholic extracts exhibited significant antimicrobial activity at concentrations of 50, 75, and 100 µg/ml, while the aqueous extract showed activity only at the highest concentration tested (100 µg/ml). This suggests that the root extracts of Dalbergia spinosa could be potential sources of antimicrobial agents.
Conclusion
The findings from this study highlight the antimicrobial potential of Dalbergia spinosa Roxb. root extracts, especially the benzene and alcoholic extracts, which demonstrated considerable effectiveness against a range of pathogens. The aqueous extract's limited activity at only higher concentrations indicates that it may not be as potent as the other extracts. Overall, the study supports the traditional medicinal uses of the plant and suggests that further research could lead to the development of new antimicrobial substances based on these extracts. This exploration into the antimicrobial capabilities of Dalbergia spinosa contributes to the understanding of its therapeutic applications in phytomedicine.
FAQ section (important questions/answers):
What is the focus of the study on Dalbergia spinosa?
The study investigates the antimicrobial activity of root extracts of Dalbergia spinosa against various bacteria and fungi using different extraction methods and concentrations.
What microorganisms were tested in the study of Dalbergia spinosa?
The study tested against gram-positive Staphylococcus aureus, gram-negative Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, and the fungi Candida albicans.
Which extracts of Dalbergia spinosa showed significant antimicrobial activity?
Benzene and alcoholic extracts exhibited significant antimicrobial activity, while the aqueous extract showed activity only at a higher concentration of 100 µg/ml.
What method was used to determine antimicrobial activity in the study?
The antimicrobial activity was determined using the cup plate method, measuring the zone of inhibition around the extracts after incubation with microorganisms.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Antimicrobial activity of root extracts of dalbergia spinosa roxb�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Activity:
Activity refers to the effectiveness or action of a substance—in this case, the antimicrobial activity of root extracts from Dalbergia spinosa Roxb. It is crucial to examine how these extracts inhibit the growth of various microorganisms to assess their potential as natural antimicrobial agents.
2) Science (Scientific):
Science represents the systematic study of the natural world, including biology, chemistry, and pharmacology, as applied in this research. It underlies the methodologies used for the extraction and testing of plant compounds for antimicrobial properties, showcasing the intersection of traditional knowledge and scientific validation.
3) Water:
Water serves as a solvent in the preparation of aqueous extracts from Dalbergia spinosa roots. It is integral for extracting polar compounds from the plant, allowing researchers to investigate the differing antimicrobial properties of various extracts, ultimately highlighting water's role in herbal medicine and extraction processes.
4) Discussion:
Discussion is the critical analysis of the results obtained from the study. It involves interpreting the antimicrobial activity of different extracts, understanding their implications for medicinal use, and comparing findings with existing literature. This section is essential for placing results within a broader context of scientific research.
5) Antibiotic (Antibacterial):
Antibiotic refers to substances that kill or inhibit the growth of bacteria, a fundamental concept in this study. Ciprofloxacin, a synthetic antibiotic, serves as a control to evaluate the effectiveness of natural extracts. Understanding antibiotics' role guides the exploration of alternative therapies from plant sources.
6) Medicine:
Medicine encompasses the practices and substances used to treat ailments. The study of Dalbergia spinosa root extracts highlights its potential medicinal applications, particularly in treating infections. It underscores the importance of evaluating natural products as viable alternatives or complements to conventional medical therapies in modern healthcare.
Other Science Concepts:
Discover the significance of concepts within the article: �Antimicrobial activity of root extracts of dalbergia spinosa roxb�. Further sources in the context of Science might help you critically compare this page with similair documents:
Antimicrobial activity, Zone of inhibition, Aqueous extract, Gram positive bacteria, Gram negative bacteria, Alcoholic extract, Soxhlet Apparatus, Benzene extract, Root extract, Ciprofloxacin antibiotic.