CHD Risk: Prevention and Management with Indigenous Compound
Journal name: Ancient Science of Life
Original article title: Individuals at Risk of Coronary Heart Disease (CHD), its Prevention and Management by an Indigenous Compound
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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Dr. G.P. Dubey, Dr. Aruna Agrawal, Dr. S.P. Dixit, Dr. S.R. Pathak
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Individuals at Risk of Coronary Heart Disease (CHD), its Prevention and Management by an Indigenous Compound
Year: 2000
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
Coronary heart disease (CHD) is influenced by a variety of risk factors, including hypercholesterolemia, hypertension, and psychological distress. A study involving 406 individuals aged 35 to 55 from Varanasi city identified those with single or multiple risk factors for CHD. Participants with abnormal lipid profiles and psychological issues were treated with a herbal formulation composed of Inula racemosa, Commiphora mukul, Centella asiatica, and Hypericum perforatum for six months. The findings indicated that this indigenous compound has potential cardioprotective and therapeutic effects by improving lipid profiles and psychological factors.
Impact of Herbal Treatment on Key Risk Factors
The study highlighted the significant improvement in clinical features such as anxiety, depression, and various lipid parameters among participants receiving the herbal formulation, in comparison to the placebo group. Specifically, there was a notable reduction in total cholesterol and low-density lipoprotein (LDL) cholesterol levels, alongside improvements in anxiety and depression scores, suggesting a beneficial impact on both physical and mental health. The herbal treatment not only corrected abnormalities in lipid metabolism but also appeared to alleviate psychological stressors, which are often precursors to the onset of CHD. This dual action underscores the importance of addressing both physiological and psychological aspects in managing coronary risk factors.
Conclusion
The findings of the study advocate for the use of the herbal formulation as a proactive approach in managing individuals at risk for coronary heart disease. By effectively reducing key risk factors such as hyperlipidemia and psychological stress, the formulation demonstrates its potential as a safe and efficacious alternative to conventional drug therapies. As evidence mounts regarding the effectiveness of herbal compounds in addressing both physiological and emotional health, there is a compelling case for their integration into preventive and therapeutic strategies for coronary heart disease.
FAQ section (important questions/answers):
What are the main risk factors for Coronary Heart Disease (CHD)?
The primary risk factors for CHD include hypercholesterolemia, diabetes, hypertension, obesity, smoking, age, and genetic predisposition. The presence of multiple risk factors greatly increases the likelihood of developing CHD and associated complications.
What indigenous compounds were tested for CHD management in the study?
The study tested a compound formulation containing Inula racemosa (Pushkarmool), Commiphora mukul (Guggulu), Centella asiatica (Mandukaparni), and Hypericum perforatum (Basant). These ingredients were administered over six months to individuals with identified risk factors for CHD.
What benefits were observed from the herbal formulation treatment?
Significant improvements were noted in lipid profiles, blood pressure, anxiety, and depression scores. The treatment led to a reduction in triglycerides and an increase in HDL cholesterol, indicating potential cardioprotective effects without adverse reactions.
How was the efficacy of the treatment assessed in the study?
Efficacy was assessed through clinical, biochemical, and psychological evaluations before and after treatment. Changes in lipid profiles, anxiety and depression scores, as well as blood pressure measurements were analyzed statistically to determine the treatment's effectiveness.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for âCHD Risk: Prevention and Management with Indigenous Compoundâ�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Drug:
In the context of the study, 'drug' refers to the herbal formulation that was tested for its efficacy in managing coronary heart disease (CHD) risk factors. It highlights the shift towards using natural compounds in medicine, particularly those derived from plants with established therapeutic properties, as an alternative to conventional chemical drugs.
2) Anxiety:
Anxiety is recognized in the study as one of the psychological factors that significantly impact individuals at risk for CHD. The research aimed to measure changes in anxiety levels in participants before and after treatment, demonstrating how the herbal formulation could potentially alleviate anxiety, thereby contributing to overall heart health.
3) Depression:
Depression, similar to anxiety, is addressed as a major mental health issue that can exacerbate the risk of coronary heart disease. The study included evaluation of depression scores to assess the herbal formulation's effectiveness in improving psychological well-being, suggesting a holistic approach to managing heart disease risk factors.
4) Guggulu:
Guggulu (Commiphora mukul) is included in the herbal formulation under study. It is praised for its cardioprotective properties, specifically in lipid metabolism regulation. The study emphasizes how traditional remedies like Guggulu offer potential therapeutic benefits against CHD, highlighting the significance of natural ingredients in health management.
5) Blood:
Blood parameters, such as lipid profiles and pressure readings, were critical measurement points in assessing the effectiveness of the herbal drug. The focus on blood metrics underscores the direct link between cardiovascular health and blood composition, emphasizing the formulation's role in normalizing these parameters to prevent CHD.
6) Mandukaparni (Maášá¸ĹŤkaparášÄ�, Manduka-parni, Mamdukaparni):
Mandukaparni (Centella asiatica) is one of the main ingredients in the herbal formulation. It is known for its neuroprotective and cardiotonic effects, which are relevant in addressing both the physical and psychological aspects of heart disease, as highlighted by the study in its evaluation of treatment efficacy.
7) Sharman (Ĺarma, SarmÄ, Sarma, Sharma, Ĺarman):
Sharma is mentioned as a reference point for validating the properties of the herbal ingredients used in the study. The inclusion of previous research by Sharma lends credibility to the claims made about the effectiveness of the formulation in treating heart disease risk factors.
8) Commiphora mukul:
Commiphora mukul, commonly known as Guggulu, is a key component in the tested herbal formulation. Its properties as an anti-atherotic and lipid-lowering agent are particularly relevant to the prevention and management of coronary heart disease, showcasing the potential of traditional herbal medicine.
9) Science (Scientific):
The term 'science' relates to the methodological approach of the study, which employs clinical trials and statistical analysis to evaluate the efficacy of the herbal formulation. It indicates a movement towards evidence-based practices in incorporating indigenous knowledge within the realm of modern medical science.
10) Discussion:
Discussion serves as a critical analysis segment in research papers where findings are interpreted and contextualized. In this study, the discussion reveals connections between risk factor management and the effectiveness of the herbal formulation, fostering an understanding of its implications for future therapeutic strategies.
11) Reason:
Reason relates to the rationale behind the selection of herbal compounds in the formulation. It underlines the necessity for safer, natural alternatives to synthetic drugs while addressing risk factors for coronary heart disease, emphasizing the importance of both efficacy and safety in treatment approaches.
12) Aruna (Aruáša, AruášÄ�):
Aruna is a credited author in the study, contributing to the research oversight and formulation evaluation. The mention of her name signifies collaborative efforts in the medical research field, highlighting the importance of multi-disciplinary contributions to holistic medical studies focused on community health.
13) Moth:
Moth, while not directly related to the core subject, may symbolize ideas of natural processes and ecosystems. It can represent the balance in using nature-derived therapies, reflective of the holistic approach advocated in the study which emphasizes natural remedies over synthetic solutions.
14) Mud:
Mood is intrinsically linked to psychological factors impacting individuals at risk for coronary heart disease. The study's analysis of mood changes in relation to treatment highlights the interconnectedness of mental health and heart disease, advocating for a comprehensive strategy in managing CHD through psychological wellness.
Other Science Concepts:
Discover the significance of concepts within the article: â�CHD Risk: Prevention and Management with Indigenous Compoundâ�. Further sources in the context of Science might help you critically compare this page with similair documents:
Physical exercise, Preventive measure, Statistical analysis, Psychological involvement, Early detection, Clinical efficacy, Herbal formulation, Placebo treatment, Atherosclerosis, Hypertension, Anxiety and depression, Coronary heart disease, Hypercholesterolemia, Abnormal Lipid Profile, Lipid disorders, Risk factor, Cardiotonic, Cardioprotective effect.