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Antifungal effects of herbal seed oils on otomycosis fungi.

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Journal name: Ancient Science of Life
Original article title: Antimycotic effect of fixed oils treated with herbal seeds on the growth of fungi causing otomycosis
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:

This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.

Author:

Sudhir Jain, S.C. Agarwal, Seema Malaiya


Ancient Science of Life:

(A quarterly multi-disciplinary scientific research journal in Ayurveda)

Full text available for: Antimycotic effect of fixed oils treated with herbal seeds on the growth of fungi causing otomycosis

Year: 1993

Copyright (license): CC BY-NC-SA


Download the PDF file of the original publication


Summary of article contents:

Introduction

The study investigates the antimycotic effects of various fixed oils combined with herbal seeds on pathogenic fungi responsible for otomycosis, a fungal infection of the outer ear. Specifically, the research focuses on five fungi: Aspergillus niger, A. flavus, Absidia corymbifera, Penicillium nigricans, and Candida albicans, which were isolated from patients experiencing external ear infections. Common oils, including coconut, mustard, groundnut, and soyabean, were mixed with herbal seeds such as trigonella, ajwoin, mustard, and garlic to evaluate their effectiveness in inhibiting spore germination of these fungi.

Efficacy of Mustard Oil with Herbal Seeds

One of the key findings of the study highlights the potent antifungal properties of mustard oil when mixed with herbal seeds. Experimental results indicated that this combination achieved a 100% inhibition rate in the spore germination of all tested fungi. In particular, groundnut oil combined with mustard seeds also demonstrated complete inhibition of Absidia corymbifera spores. The study observed varying levels of mycotoxicity among different oil-seed combinations, underscoring the significance of specific plant ingredients in enhancing the antifungal potency of the oils. The presence of antifungal compounds in these oils and seeds contributed to their efficacy, suggesting potential applications in the treatment of fungal infections.

Conclusion

The findings of this research underscore the potential of utilizing fixed oils and herbal seeds as natural antimycotic agents against otomycosis-causing fungi. The incorporation of these natural products may provide an alternative or complementary approach to conventional antifungal treatments. However, further investigation into the specific antifungal components present in these oils and seeds, as well as their mechanisms of action, is necessary to fully understand their therapeutic potential. The study opens avenues for future research on the application of these natural substances in pharmaceutical settings for effective fungal infection management.

FAQ section (important questions/answers):

What was the objective of the study on oils and seeds?

The study aimed to evaluate the antimycotic effects of coconut, mustard, groundnut, and soyabean oils mixed with herbal seeds on the growth of fungi causing otomycosis.

Which fungi were tested for growth inhibition in the study?

The study tested the spore germination of five pathogenic fungi: Aspergillus niger, Aspergillus flavus, Absidia corymbifera, Penicillium nigricans, and Candida albicans.

How did mustard oil perform against the tested fungi?

Mustard oil mixed with trigonella, ajwoin, mustard seeds, and garlic bulbs caused complete inhibition of spore germination in all tested fungi.

What conclusion can be drawn from the study's findings?

The findings suggest that certain plant oils and seeds may control otomycosis effectively, warranting further research for in-vivo applications.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Antifungal effects of herbal seed oils on otomycosis fungi.�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Mustard:
Mustard refers to the seeds from the mustard plant, which were found to have significant antifungal properties. In the study, mustard seeds mixed with different oils led to complete inhibition of spore germination of test fungi, demonstrating their effectiveness in the treatment of fungal infections such as otomycosis.

2) Coconut (Cocoanut):
Coconut oil is derived from coconut fruit and is evaluated in the study for its antimycotic effects. Although it was found to be less effective compared to mustard oil, it showed some antifungal properties when combined with certain seeds, suggesting potential for use in topical antifungal treatments.

3) Garlic:
Garlic is acknowledged for its known antifungal and antibacterial properties. In the context of this study, garlic bulbs, when mixed with oils, contributed to the inhibition of spore germination in pathogenic fungi, highlighting its traditional use in treating ear infections and supporting the therapeutic potential of garlic.

4) Mustard oil:
Mustard oil, extracted from mustard seeds, demonstrated remarkable antifungal efficacy in this study. When combined with various plant parts, it resulted in complete suppression of spore germination in several fungi implicated in otomycosis, validating its role as a therapeutic agent in mycotic infections.

5) Activity:
Activity pertains to the effectiveness of the tested oils and plant parts in inhibiting the growth of pathogenic fungi. The study focused on evaluating the antifungal activity of various oils mixed with herbal seeds, showcasing the potential applications of natural substances in treating fungal infections.

6) Toxicity:
Toxicity refers to the capability of the oils and mixed plant parts to inhibit fungal growth, measured as spore germination rates. The study highlighted varying levels of fungitoxicity in oils and combinations tested, indicating their potential utility in preventing and managing fungal infections.

7) Sharman (Śarma, Sarmā, Sarma, Sharma, Śarman):
Sharma is likely a reference to one of the authors or researchers whose work is cited in relation to the medicinal properties of plant compounds. Their previously reported findings contributed to the understanding of fungitoxic properties of specific plants, enhancing the relevance of the study.

8) Antibiotic (Antibacterial):
Antibiotic refers to substances that combat bacterial growth. The study references the antibiotic activity of trigonella seeds against certain fungi, suggesting a broader use of plant extracts in developing new antifungal agents while reinforcing the connection between antibiotic and antifungal properties in natural remedies.

9) Inflammation:
Inflammation is a biological response to harmful stimuli, which can occur in infections like otomycosis. The study addresses the need to control fungal growth to alleviate inflammation in the ear canal, emphasizing the importance of plant-based antimycotic treatments in managing infection-related inflammation.

10) Discussion:
Discussion provides a critical analysis of the experimental findings, interpreting the implications of the results observed. It emphasizes the significance of combining specific oils with herbal seeds, proposing further investigation into their antifungal components and potential application in therapeutic contexts.

11) Flavonoid:
Flavonoid constitutes a group of plant metabolites with potential health benefits. The study suggests that compounds such as flavonoids present in trigonella seeds may contribute to their antifungal effects, advocating for the exploration of these and other phytochemicals in combating fungal pathogens.

12) Science (Scientific):
Science encompasses the systematic study of the natural world, which includes the exploration of medicinal properties of plants. This study exemplifies scientific research methodology in investigating the antifungal potential of herbal oils and seeds, contributing to the knowledge base of integrative medicine.

13) Insect:
Insect refers to pests that might be deterred by certain aromatic compounds present in plants like trigonella. These insect-repellent properties can be beneficial in traditional healthcare practices while also enhancing the plants' antifungal effects, merging pest control with infection management.

14) Glass:
Glass, often used in laboratory settings, refers to the use of glass slides and dishes for conducting experiments. Precise equipment like glass instruments is essential for maintaining sterile conditions and accurately observing the germination and growth of fungal spores during the study.

15) Water:
Water provides the necessary moisture for spore germination in the experiment. Its role is crucial in creating an appropriate environment for fungal growth in the lab setup, reinforcing the importance of controlling external conditions in microbiological studies.

16) Drug:
Drug denotes a substance used for medicinal purposes. The study seeks to explore the potential of herbal oils and their active ingredients as natural drugs, proposing a pathway for integrating these plant-based remedies into pharmaceutical formulations aimed at treating fungal infections.

Other Science Concepts:

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Discover the significance of concepts within the article: �Antifungal effects of herbal seed oils on otomycosis fungi.�. Further sources in the context of Science might help you critically compare this page with similair documents:

Mustard oil, Coconut oil, Incubation period, Groundnut oil, Pathogenic fungi, Otomycosis, Spore germination, Fixed oil, In vitro condition, Garlic bulbs.

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