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Indian plants and plant products with antifertility effect

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Journal name: Ancient Science of Life
Original article title: Indian plants and plant products with antifertility effect
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:

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Author:

G. V. Satyavati


Ancient Science of Life:

(A quarterly multi-disciplinary scientific research journal in Ayurveda)

Full text available for: Indian plants and plant products with antifertility effect

Year: 1984

Copyright (license): CC BY-NC-SA


Download the PDF file of the original publication


Summary of article contents:

Introduction

The article reviews extensive research on Indian plants exhibiting antifertility properties, compiling studies conducted by various institutes and independent investigators. Despite the wealth of literature on the subject, the available clinical data remains limited. Notably, the author discusses the findings regarding not just the plants effective at inhibiting fertility, but also those that display varying degrees of anti-implantation and abortifacient activities, shedding light on their potential applications in fertility regulation.

Analysis of Antifertility Effects in Plants

One significant aspect of the research highlighted is the antifertility activity observed in female reproductive studies. The review indicates that certain plants, such as Albissia lebbeck and Aloe barbadensis, are recognized for their potent anti-ovulatory effects. A wide array of plants, totaling twenty-eight, exhibited anti-implantation activities, while others were noted for their abortifacient effects. For instance, Aristolochia indica stands out due to its in-depth analysis, revealing various active constituents associated with antifertility properties, including aristolic acid and its derivatives. The document intricately discusses the dualities observed in some plant effects—where the same substance can exhibit antifertility properties in one study yet show inactivity in another, such as with Embelia ribes.

Conclusion

The findings presented in this review emphasize the diverse antifertility properties of various Indian plants and the complexity surrounding their effectiveness. While certain plants have demonstrated significant potential for controlling fertility, variability in results and limited clinical data necessitate more in-depth research. Continued investigation into the pharmacological actions and mechanisms of these plants is crucial for understanding their safe and effective use in fertility regulation and tailoring treatments in reproductive health. Thus, while the body of evidence is compelling, further exploration is needed to establish firm clinical applications.

FAQ section (important questions/answers):

What are some Indian plants with antifertility effects in women?

Research has identified several plants with antifertility activity, such as Albissia lebbeck, Aloe barbadensis, Mentha arvensis, and Vitex negundo. Clinical data is limited, but studies suggest varying degrees of anti-ovulatory, anti-implantation, and abortifacient activities among these plants.

Are there any documented studies on antifertility plants?

While extensive research has been conducted, documented clinical data on antifertility plants remains scarce. Isolated studies have shown certain plants exhibit significant effects; however, comprehensive clinical validation is still needed to confirm these findings.

Which plants have shown antifertility activity in males?

Notable antifertility plants for males include Azadirachta indica, Aristolochia indica, and Embelia ribes. These have shown antispermatogenetic effects or reduced testosterone levels without significantly impacting sperm production, according to available research.

What research supports the use of Ayurvedic preparations for antifertility?

Ayurvedic preparations such as Garbhanivaranaushadham and Ayush�47 have shown antifertility effects in animal studies. Ingredients from these formulations, like Saraca indica and Embelia ribes, have demonstrated significant outcomes in various trials, although human clinical assessments are limited.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Indian plants and plant products with antifertility effect�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Activity:
Activity in this context refers to the biological or pharmacological efficacy of various plant extracts and compounds to produce antifertility, abortifacient, or other reproductive effects, as observed in various studies documented in the text. It highlights how these plants can affect fertility in males and females through various mechanisms.

2) Embelia ribes:
Embelia ribes is identified in the text as a plant associated with antifertility effects, particularly through a compound called embelin. Various studies show conflicting results regarding its efficacy, with some highlighting its potential as an antifertility agent, while others find no significant effects.

3) Sharman (Åšarma, SarmÄ, Sarma, Sharma, Åšarman):
Sharma is mentioned in the context of studies exploring the antifertility and related properties of plants, including Daucus carota and others. Research in this field contributes to understanding the mechanisms behind plant-based antifertility effects and assists in developing herbal contraceptives.

4) Gupta (GuptÄ):
Gupta is frequently referenced in studies that outline the pharmacological activities of certain plants with antifertility properties. The author's investigations into the effects of various extracts, including those from H. rosa sinensis and V. longum, contribute crucial data to the literature on herbal medicine.

5) Anana (Ä€nana, Ä€nanÄ, AnanÄ, Anaṇa, Āṅana):
Here, 'Anana' refers to Ananas comosus, commonly known as pineapple. It is noted for its abortifacient effects derived from its unripe fruits. The text emphasizes the significance of its active compounds that may inhibit pregnancy when administered during specific gestational periods.

6) Devi (Devī):
Devi appears alongside other researchers in the context of studies on the abortifacient properties of plant extracts, particularly highlighting the teratogenic effects of Carica papaya when administered to pregnant rats. It signifies the collaborative nature of research in this field.

7) Plumbago zeylanica:
Plumbago zeylanica is recognized for its significant anti-implantation and abortifacient activities documented in the studies cited. Its effects on the reproductive system indicate the potential for therapeutic applications in contraception, showcasing the plant's relevance in herbal pharmacology.

8) Jasmine:
Jasmine, specifically the flower J. pubescens, demonstrates lactogenic suppression effects observed in studies. The mechanism of action leading to reduced milk production among lactating mice illustrates the broader implications of scent and olfactory stimulation on hormonal balance in mammals.

9) Saha (SÄha, Shaha):
Saha is cited in the research findings discussing the antifertility effects of extracts from Aristolochia indica and its active components. His work contributes valuable insights into the potential risks and benefits of using this plant for fertility regulation.

10) Hand:
In this context, �hand� likely denotes possession or involvement in herbal preparation and utilization. It symbolizes the traditional and practical aspect of utilizing these plant-based medicines to handle reproductive health issues among populations relying on ancient remedies.

11) Azadirachta indica:
Azadirachta indica, also known as Neem, is recognized for its antifertility impact, particularly in male subjects. Its effectiveness highlights the diversity of plant-based reproductive health options and necessitates further research into its applications within family planning.

12) Butea monosperma:
Butea monosperma is denoted as a plant with antifertility effects, reflecting its potential applications in herbal medicine. Its bioactive compounds, within specified doses, may influence reproductive processes, contributing to the overall study of plant-based contraceptive agents.

13) Curcuma longa:
Curcuma longa, commonly known as turmeric, is discussed in terms of its antifertility effects. This explores the broader implications of herbal constituents in relation to reproductive health, emphasizing the significance of traditional medicinal practices.

14) Piper longum:
Piper longum is mentioned as contributing to antifertility activity when combined with Embelia ribes. Its combined effects on pregnancy in rats highlight the importance of studying multi-ingredient herbal formulations in understanding and harnessing their reproductive health potential.

15) Terminalia arjuna:
Terminalia arjuna is identified as a plant with noted uterine stimulant properties in conjunction with its antifertility effects, emphasizing its role in Ayurvedic practices and the therapeutic potential of its active compounds for managing reproductive health.

16) Arjuna:
Arjuna refers to Terminalia arjuna, emphasizing its diverse applications in traditional medicine related to reproductive health. Research supports its use in treatments aiming to enhance uterine tone and manage fertility in various settings.

17) Pigeon:
Pigeon is mentioned in studies investigating the effects of various plant extracts on reproductive health, particularly in relation to cannabis. It signifies the comparative study across species to evaluate the impact of herbal constituents on fertility.

18) Cita:
Sida carpinifolia is recognized for its antifertility effects in studies. Its significance reflects a broader understanding of diverse plant species contributing to herbal approaches in managing fertility and reproductive health.

19) Dolichos biflorus:
Dolichos biflorus is highlighted as a plant whose extracts showed no antifertility activity, indicating variability in plant efficacy within the pharmacological studies. This emphasizes the need for systematic evaluation of plant compounds for reproductive influences.

20) Adhatoda vasica:
Adhatoda vasica is noted for containing vasicine, an alkaloid with uterotonic and potential abortifacient effects. This reinforces the significance of exploring various plant-based remedies within herbal pharmacology and their applications in reproductive health.

21) Ocimum sanctum:
Ocimum sanctum, or Holy Basil, is significant in traditional medicine and may have regulatory effects on fertility. Its roles in reproductive health also highlight the importance of integrating herbal knowledge into modern medical practices.

22) Asparagus racemosus:
Asparagus racemosus is valued for its lactogenic properties, showcasing its importance in encouraging milk production. It represents the dual nature of many plants in promoting fertility in some aspects while serving as a contraceptive in others.

23) Abrus precatorius:
Abrus precatorius is characterized by its potent antifertility effects, underscoring the importance of evaluating its bioactive components in contributing to plant-based contraceptive methods. This emphasizes the need for careful study of such plants in reproductive health.

24) Pharmacology:
Pharmacology in this context involves the study of plant extracts and compounds to understand their medicinal properties, particularly regarding antifertility effects. The interplay between traditional knowledge and scientific research demonstrates the potential for innovative contraceptive solutions.

25) Rajashekhara (RÄjaÅ›ekhara, Rajan-shekhara):
Rajasekhara is mentioned amidst researchers reporting on plant-derived substances with antifertility effects. The acknowledgment of multiple contributors emphasizes collaborative efforts in the scientific investigation of herbal medicines and their applications.

26) Substance:
Substance encapsulates the various phytochemicals and extracts isolated from plants that exhibit antifertility, abortifacient, or other health-related effects. The significance of studying these substances lies in their potential therapeutic uses in reproductive health.

27) Flavonoid:
Flavonoid refers to a class of compounds found in many plants known for their health benefits, including antifertility effects. The presence of flavonoids in various plants highlights the chemical diversity that contributes to their medicinal properties.

28) Science (Scientific):
Science in this context refers to the systematic study and understanding of plant properties and their applications in fertility regulation. It embodies the integration of traditional practices with modern methodologies to inform future research in herbal medicine.

29) Laksha (LÄká¹£Ä�):
Laksha refers to a resinous substance associated with Laccardia lacca, which is discussed for its anti-implantation effects. Its significance underscores the diversity of bioactive compounds sourced from different plants and their potential applications in reproductive health.

30) Mahana (MÄhana, MahÄna):
Mahana is mentioned in the context of the plant Physalis minima, which exhibits abortifacient properties. This emphasizes collaboration among researchers to elucidate the effects of various plant extracts in reproductive health.

31) Insect:
In the context of obtaining compounds such as Laksha, insects play a role in the life cycle of certain plants. The interaction between flora and fauna showcases the complexity of ecological relationships affecting the availability of medicinal substances.

32) Liquor:
Liquor, in terms of herbal extracts, pertains to the solvent or vehicle used for extracting active compounds from plants. The method of extraction can significantly affect the potency and profile of the resulting herbal medicine.

33) Costus:
Costus speciosus is discussed in the context of its rhizome exhibiting ecological effects but lacking subsequent investigations into abortifacient properties. This points to the need for comprehensive studies on related species to broaden understanding of their pharmacological potential.

34) Ayus (Ä€yus, Ayush):
Ayush references a compound Ayurvedic preparation noted for its anti-implantation effects in clinical studies. This illustrates the significance of traditional formulations within the context of modern reproductive health applications and trials.

35) Sugar:
Sugar, often used in herbal formulations, may serve not only as a sweetener but also as a functional ingredient that could enhance the efficacy of the active compounds. Its role reflects the fusion of dietary elements within medicinal practices.

36) Borax:
Borax is included in a compound Ayurvedic preparation noted for antifertility effects. Its significance lies in traditional uses and essential roles within formulations aimed at women's reproductive health, underlining the historical context of herbal medicine.

Other Science Concepts:

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Discover the significance of concepts within the article: �Indian plants and plant products with antifertility effect�. Further sources in the context of Science might help you critically compare this page with similair documents:

Clinical data, Abortifacient activity, Ayurvedic practitioner, Antifertility effect, Lactogenic effect, Antifertility activity, Alcoholic extract, Spermicidal activity, Estrogenic activity, Uterine bleeding, Saponin, Cervical dilator, Anti-implantation activity, Plant product, Testicular function.

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