Significance of Trial runs
Trial runs are preliminary tests essential for evaluating and optimizing chromatographic conditions in HPLC method development. They involve conducting experimental trials to assess the method's effectiveness and reliability before final validation. These procedures are critical during the method development phase, ensuring that the proposed methods meet necessary criteria and performance standards. Overall, trial runs play a vital role in the successful establishment of reliable chromatographic techniques.
Synonyms: Experimentation, Practice runs, Rehearsals
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The concept of Trial runs in scientific sources
Trial runs are experimental procedures vital for method development, optimizing conditions and assessing the effectiveness of proposed methods, as indicated by regional sources. They ensure that the methods are refined before full implementation.
From: World Journal of Pharmaceutical Research
(1) Preliminary tests carried out to assess the effectiveness of method parameters, leading to the optimization of the chromatographic conditions.[1] (2) Experimental trials conducted to test the effectiveness and reliability of a developed HPLC method before final validation.[2] (3) Experimental procedures conducted during method development to optimize conditions and evaluate the effectiveness of the proposed methods.[3]