Significance of Sequence alignment
Sequence alignment is a bioinformatics method utilized to organize DNA, RNA, or protein sequences to uncover similarities that may signify functional, structural, or evolutionary links. This technique is essential for evaluating the relationships between query sequences and allows for the calculation of percentage identity and similarity among nucleotides. By effectively arranging these sequences, researchers can identify crucial regions of similarity that provide insights into their functions and evolutionary history.
Synonyms: Sequence similarity
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The concept of Sequence alignment in scientific sources
Sequence alignment is the method of arranging protein or nucleotide sequences to uncover similarities, highlighting functional and evolutionary connections between them. This process is vital for understanding biological relationships and comparative genomics.
From: The Malaysian Journal of Medical Sciences
(1) Sequence alignment of the HCV isolates showed the addition of guanine (G) nucleotide in the de novo occult HCV sequences.[1]