Significance of Rat model
The rat model refers to the use of laboratory rats as experimental subjects in various studies aimed at understanding diseases and evaluating treatments. These models are employed for research on motor impairments, pharmacological effects, wound healing, and conditions like celiac disease and Alzheimer's. Researchers utilize rats because of their anatomical similarities to humans, making them suitable for assessing the impact of various drugs, herbal remedies, and other interventions in clinical research and pharmacology.
Synonyms: Rodent model, Rat study, Animal model, Laboratory rat, Murine model
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The concept of Rat model in scientific sources
The Rat model is an experimental framework involving rats, particularly Charles Foster albino rats, utilized to investigate developmental toxicology and the teratogenic effects of substances like Fumaria indica in research studies.
From: The Malaysian Journal of Medical Sciences
(1) The use of rats in the study to simulate the effects of a condition, in this case, hepatotoxicity, to test the effectiveness of a treatment.[1] (2) These are laboratory animals, specifically rats, that are used to study diseases and test treatments, often used to understand motor impairments.[2] (3) Rat model of celiac disease shows a protective effect of ghrelin, as reported by the presented research and findings.[3] (4) These are experimental systems used to study the effects of various treatments, such as local anesthetics for postoperative adhesions and intraperitoneal EMLA for abdominal adhesion prevention.[4] (5) A model of Alzheimer's disease that was used to study the effects of certain treatments and the mechanisms of the disease.[5]